About the Authors

João Filipe Menino

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Margarida Saraiva

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Ana G. Gomes-Alves

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Diogo Lobo-Silva

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Mark Sturme

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Jéssica Gomes-Rezende

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Ana Laura Saraiva

Affiliation EUVG - Escola Universitária Vasco da Gama, Castelo Viegas, Coimbra, Portugal

Gustavo H. Goldman

Affiliation Laboratório Nacional de Ciência e Tecnologia do Bioetanol – CTBE, Campinas, São Paulo, Brazil, and Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, São Paulo, Brasil

Cristina Cunha

Affiliation Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy

Agostinho Carvalho

Affiliation Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy

Luigina Romani

Affiliation Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy

Jorge Pedrosa

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

António Gil Castro

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Fernando Rodrigues

frodrigues@ecsaude.uminho.pt

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: M. Saraiva, A. Carvalho, A.G. Castro, F. Rodrigues. Performed the experiments: J.F. Menino, A.G. Gomes-Alves, D. Lobo-Silva, M. Sturme, G.H. Goldman, J. Gomes-Rezende, A.L. Saraiva, J. Pedrosa. Analyzed the data: J.F. Menino, C. Cunha, A. Carvalho, L. Romani, A.G. Castro, F. Rodrigues. Contributed reagents/materials/analysis tools: F. Rodrigues. Wrote the paper: J.F. Menino, M. Saraiva, A.G. Castro, F. Rodrigues.