About the Authors

Shamila S. Gunatilleke

Contributed equally to this work with: Shamila S. Gunatilleke, Claudia M. Calvet

Affiliations Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America

Claudia M. Calvet

Contributed equally to this work with: Shamila S. Gunatilleke, Claudia M. Calvet

Affiliations Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Cellular Ultra-Structure Laboratory, Oswaldo Cruz Institute (IOC), FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil

Jonathan B. Johnston

Affiliation Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America

Chiung-Kuang Chen

Affiliations Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America

Grigori Erenburg

Affiliation King's University College at the University of Western Ontario, London, Ontario, Canada

Jiri Gut

Affiliations Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

Juan C. Engel

Affiliations Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America

Kenny K. H. Ang

Affiliation Small Molecule Discovery Center, University of California San Francisco, San Francisco, California, United States of America

Joseph Mulvaney

Affiliation Small Molecule Discovery Center, University of California San Francisco, San Francisco, California, United States of America

Steven Chen

Affiliation Small Molecule Discovery Center, University of California San Francisco, San Francisco, California, United States of America

Michelle R. Arkin

Affiliation Small Molecule Discovery Center, University of California San Francisco, San Francisco, California, United States of America

James H. McKerrow

Affiliations Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America

Larissa M. Podust

larissa.podust@ucsf.edu

Affiliations Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JHM MRA LMP. Performed the experiments: SSG CMC JBJ CKC JG JCE KKHA. Analyzed the data: SSG CMC JBJ CKC GE KKHA JM SC LMP. Contributed reagents/materials/analysis tools: JBJ GE JCE JM SC MRA JHM LMP. Wrote the paper: SSG CMC LMP.