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Viral replication

Neuron-associated retroelement-derived protein Arc/Arg3.1 assists in the early stages of alphaherpesvirus infection in human neuronal cells

Hiroko Kobayashi, Mitsuki Yasukochi, Masayuki Horie, Yasuko Orba, Hirofumi Sawa, Kan Fujino, Satoshi Taharaguchi

published 12 Dec 2024

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Amino acid T25 in the substrate-binding domain of SARS-CoV-2 nsp5 is involved in viral replication in the mouse lung

Yoshiro Sugiura, Kenta Shimizu, Tatsuki Takahashi, Shiori Ueno, Haruka Tanigou, Sodbayasgalan Amarbayasgalan, Wataru Kamitani

published 06 Dec 2024

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Integrated study of Quercetin as a potent SARS-CoV-2 RdRp inhibitor: Binding interactions, MD simulations, and In vitro assays

Ahmed M. Metwaly, Esmail M. El-Fakharany, Aisha A. Alsfouk, Ibrahim M. Ibrahim, Eslam B. Elkaeed, Ibrahim. H. Eissa

published 03 Dec 2024

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Repurposing of drug candidates against Epstein–Barr virus: Virtual screening, docking computations, molecular dynamics, and quantum mechanical study

Mahmoud A. A. Ibrahim, Alaa M. A. Hassan, Eslam A. R. Mohamed, Gamal A. H. Mekhemer, Peter A. Sidhom, Mohamed A. El-Tayeb, Shahzeb Khan, Tamer Shoeib, Mahmoud E. S. Soliman, Alaa H. M. Abdelrahman

published 15 Nov 2024

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Genetic and pathogenic potential of highly pathogenic avian influenza H5N8 viruses from live bird markets in Egypt in avian and mammalian models

Yassmin Moatasim, Basma Emad Aboulhoda, Mokhtar Gomaa, Ahmed El Taweel, Omnia Kutkat, Mina Nabil Kamel, Mohamed El Sayes, Mohamed GabAllah, Amany Elkhrsawy, Hend AbdAllah, Ahmed Kandeil, Mohamed Ahmed Ali, Ghazi Kayali, Rabeh El-Shesheny

published 29 Oct 2024

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Effect of a loss of the mda5/ifih1 gene on the antiviral resistance in a Chinook salmon Oncorhynchus tshawytscha cell line

Catherine Collins, Lise Chaumont, Mathilde Peruzzi, Nedim Jamak, Pierre Boudinot, Julia Béjar, Patricia Moreno, Daniel Álvarez Torres, Bertrand Collet

published 14 Oct 2024

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Transcriptomic analyses of host-virus interactions during in vitro infection with wild-type and glycoprotein g-deficient (ΔgG) strains of ILTV in primary and continuous cell cultures

Gayathri Gopakumar, Andrés Diaz-Méndez, Mauricio J. C. Coppo, Carol A. Hartley, Joanne M. Devlin

published 11 Oct 2024

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Tracking the emergence of a novel genotype of Decapod hepanhamaparvovirus in shrimp using laser microdissection and next generation sequencing

Roberto Cruz-Flores, Arun K. Dhar

published 10 Oct 2024

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Aphid-mediated beet yellows virus transmission initiates proviral gene deregulation in sugar beet at early stages of infection

Roxana Hossain, Glenda Willems, Niels Wynant, Simon Borgolte, Kristof Govaerts, Mark Varrelmann

published 01 Oct 2024

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The heat shock protein 90 inhibitor RGRN-305 attenuates SARS-CoV-2 spike protein-induced inflammation in vitro but lacks effectiveness as COVID-19 treatment in mice

Hakim Ben Abdallah, Giorgia Marino, Manja Idorn, Line S. Reinert, Anne Bregnhøj, Søren Riis Paludan, Claus Johansen

published 26 Sep 2024

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Small extracellular vesicles from the human endothelial cell line EA.hy 926 exert a self-cell activation and modulate DENV-2 genome replication and infection in naïve endothelial cells

María-Angélica Calderón-Peláez, L. Johana Madroñero, Jaime E. Castellanos, Myriam L. Velandia-Romero

published 26 Sep 2024

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Detection and prevalence of a novel Bandavirus related to Guertu virus in Amblyomma gemma ticks and human populations in Isiolo County, Kenya

Hellen Koka, Solomon Langat, Samuel Oyola, Faith Cherop, Gilbert Rotich, James Mutisya, Victor Ofula, Konongoi Limbaso, Juliette R. Ongus, Joel Lutomiah, Rosemary Sang

published 20 Sep 2024

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Virus production in shallow groundwater at the bank of the Danube River

Daniel Pleyer, Christian Griebler, Christian Winter

published 29 Aug 2024

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