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Viral replication

The gag-like gene RTL8 antagonizes PEG10-mediated virus like particles

Will Campodonico, Harihar M. Mohan, Phuoc T. Huynh, Holly H. Black, Cristina I. Lau, Henry L. Paulson, Lisa M. Sharkey, Alexandra M. Whiteley

published 30 Dec 2024

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Bioinformatics analysis of myelin-microbe interactions suggests multiple types of molecular mimicry in the pathogenesis of multiple sclerosis

Ali Bigdeli, Mostafa Ghaderi-Zefrehei, Bluma J. Lesch, Mehrdad Behmanesh, S. Shahriar Arab

published 30 Dec 2024

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Eilat virus isolated from Culex univittatus mosquitoes from the Namibian Zambezi Region influences in vitro superinfection with alpha- and flaviviruses in a virus-species-dependent manner

Heiko D. Guggemos, Anne Kopp, Katrin Voigt, Matthias Fendt, Selina L. Graff, John K. E. Mfune, Christian Borgemeister, Sandra Junglen

published 20 Dec 2024

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Neuron-associated retroelement-derived protein Arc/Arg3.1 assists in the early stages of alphaherpesvirus infection in human neuronal cells

Hiroko Kobayashi, Mitsuki Yasukochi, Masayuki Horie, Yasuko Orba, Hirofumi Sawa, Kan Fujino, Satoshi Taharaguchi

published 12 Dec 2024

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Amino acid T25 in the substrate-binding domain of SARS-CoV-2 nsp5 is involved in viral replication in the mouse lung

Yoshiro Sugiura, Kenta Shimizu, Tatsuki Takahashi, Shiori Ueno, Haruka Tanigou, Sodbayasgalan Amarbayasgalan, Wataru Kamitani

published 06 Dec 2024

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Integrated study of Quercetin as a potent SARS-CoV-2 RdRp inhibitor: Binding interactions, MD simulations, and In vitro assays

Ahmed M. Metwaly, Esmail M. El-Fakharany, Aisha A. Alsfouk, Ibrahim M. Ibrahim, Eslam B. Elkaeed, Ibrahim. H. Eissa

published 03 Dec 2024

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Repurposing of drug candidates against Epstein–Barr virus: Virtual screening, docking computations, molecular dynamics, and quantum mechanical study

Mahmoud A. A. Ibrahim, Alaa M. A. Hassan, Eslam A. R. Mohamed, Gamal A. H. Mekhemer, Peter A. Sidhom, Mohamed A. El-Tayeb, Shahzeb Khan, Tamer Shoeib, Mahmoud E. S. Soliman, Alaa H. M. Abdelrahman

published 15 Nov 2024

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Genetic and pathogenic potential of highly pathogenic avian influenza H5N8 viruses from live bird markets in Egypt in avian and mammalian models

Yassmin Moatasim, Basma Emad Aboulhoda, Mokhtar Gomaa, Ahmed El Taweel, Omnia Kutkat, Mina Nabil Kamel, Mohamed El Sayes, Mohamed GabAllah, Amany Elkhrsawy, Hend AbdAllah, Ahmed Kandeil, Mohamed Ahmed Ali, Ghazi Kayali, Rabeh El-Shesheny

published 29 Oct 2024

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Effect of a loss of the mda5/ifih1 gene on the antiviral resistance in a Chinook salmon Oncorhynchus tshawytscha cell line

Catherine Collins, Lise Chaumont, Mathilde Peruzzi, Nedim Jamak, Pierre Boudinot, Julia Béjar, Patricia Moreno, Daniel Álvarez Torres, Bertrand Collet

published 14 Oct 2024

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Transcriptomic analyses of host-virus interactions during in vitro infection with wild-type and glycoprotein g-deficient (ΔgG) strains of ILTV in primary and continuous cell cultures

Gayathri Gopakumar, Andrés Diaz-Méndez, Mauricio J. C. Coppo, Carol A. Hartley, Joanne M. Devlin

published 11 Oct 2024

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Tracking the emergence of a novel genotype of Decapod hepanhamaparvovirus in shrimp using laser microdissection and next generation sequencing

Roberto Cruz-Flores, Arun K. Dhar

published 10 Oct 2024

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Aphid-mediated beet yellows virus transmission initiates proviral gene deregulation in sugar beet at early stages of infection

Roxana Hossain, Glenda Willems, Niels Wynant, Simon Borgolte, Kristof Govaerts, Mark Varrelmann

published 01 Oct 2024

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The heat shock protein 90 inhibitor RGRN-305 attenuates SARS-CoV-2 spike protein-induced inflammation in vitro but lacks effectiveness as COVID-19 treatment in mice

Hakim Ben Abdallah, Giorgia Marino, Manja Idorn, Line S. Reinert, Anne Bregnhøj, Søren Riis Paludan, Claus Johansen

published 26 Sep 2024

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