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Viral replication

The interaction of RNA G-quadruplexes from the influenza A virus vRNA with TMPyP4 and BRACO-19 ligands

Maria Nalewaj, Joanna Sliwiak, Karolina Zielinska, Pawel Zmora, Dorota Niedziałek, Grzegorz Wieczorek, Elzbieta Kierzek, Marta Szabat

published 19 Nov 2025

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Toward an all-in-one recombinant adeno-associated virus vector for functionally ablating the prion gene using CRISPR-Cas technology

Claire Verkuyl, Ari Belotserkovsky, Thomas Zerbes, Declan Williams, Medha R. Krishnan, Sabrina Zhu, Sophie Grunnesjӧ, Shehab Eid, Cunjie Zhang, Wenda Zhao, Leo Xu, Eleanore Lin, Teaghan O’Shea, Benjamin Draper, Andreas Jungman, Patrick Most, Gerold Schmitt-Ulms

published 07 Nov 2025

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Endocervix exhibits greater susceptibility to HIV-1 infection compared to ectocervix following ex vivo exposure to Transmitted/Founder HIV-1 variants

Robert Langat, Michael D. McRaven, Ramon Lorenzo-Redondo, Teresia Muhomah, Ann M. Carias, Muhammad Shoaib Arif, Matrona Mbendo Akiso, Marianne Mureithi, Omu Anzala, Jill Gilmour, Sarah Joseph, Thomas J. Hope

published 05 Nov 2025

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Sequestration and suppressed synthesis of oncogenic HMGA1 using engineered adenoviruses decreases human pancreatic and breast cancer cell characteristics

Md. Sharif Hasan, Shuisong Ni, Fatema B. Kamal, Megan F. Blossey, Eian Vargas, Margaret B. Bogomolny, Trang Dinh, Michael A. Kennedy

published 03 Nov 2025

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Cytomegalovirus reactivation in mechanically ventilated patients with or without SARS-CoV-2 infection: A retrospective cohort study

Octave Cannac, Vanessa Pauly, Christine Zandotti, Léa Luciani, Paul-Rémi Petit, Xavier de Lamballerie, Rémi Charrel, Laurent Papazian, Damien Barrau, Geoffray Agard, Sami Hraiech

published 27 Oct 2025

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Influence of climate and heatwaves on dengue transmission in Sao Paulo and Natal, Brazil

Camila Lorenz, Rita Yuri Ynoue, Adriana Gioda, Thiago Nogueira

published 24 Oct 2025

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Quantitative analysis of proteomic changes in two monoclonal suspension MDCK cell lines infected with human influenza A virus (H1N1)

Jan Küchler, Tilia Zinnecker, Patrick Hellwig, Maximilian Wolf, Dirk Benndorf, Yvonne Genzel, Udo Reichl

published 21 Oct 2025

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In-silico identification of host-key-genes associated with dengue-virus-infections highlighting their pathogenetic mechanisms and therapeutic agents

Md. Abdul Latif, Md. Al Noman, Reaz Ahmmed, Md. Sanoar Hossain, Md. Foysal Ahmed, Md. Al Amin Pappu, Md. Shariful Islam, Tasfia Noor, Md. Hadiul Kabir, Md. Nurul Haque Mollah

published 07 Oct 2025

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Risk of hepatitis B virus reactivation in the treatment of HBsAg and HBV DNA double-negative lymphoma patients

Lan Chen, Zihuan Lu, Xinqiang Zhang, Jinxin Lai, Ge Huang, Youwei Zheng

published 17 Sep 2025

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HIV-1 controllers possess a unique CD8⁺ T cell activation phenotype and loss of control is associated with increased expression of exhaustion markers

Amber D. Jones, Zachary Capriotti, Erin Santos, Angel Lin, Rachel Van Duyne, Stephen Smith, Zachary Klase

published 28 Aug 2025

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Vitamin D enhances antiviral responses in dengue virus-infected macrophages by modulating early-response gene expression

Yordi Sebastián Tamayo-Molina, Juan Felipe Valdés-López, Geysson J. Fernandez, Silvio Urcuqui-Inchima

published 21 Aug 2025

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To be or not to be a virus: A novel chimeric circular Rep-encoding single stranded DNA virus with interfamilial gene exchange illustrates the considerable evolutionary capacity of ssDNA viruses

Sélim Ben Chéhida, Sylvain Lacroix, Murielle Hoareau, Babbitha Fenelon, Arvind Varsani, Darren P. Martin, Pierre-Yves Teycheney, Pierre Lefeuvre, Jean-Michel Lett

published 18 Aug 2025

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Amino acid residues 655 and 969 in the spike protein of Omicron subvariant BA.1 control use of TMPRSS2 versus Cathepsin L dependent entry pathways and cell tropism

Cheila Rocha, Prerna Arora, Lu Zhang, Anzhalika Sidarovich, Luise Graichen, Anna-Sophie Moldenhauer, Stefan Pöhlmann, Markus Hoffmann

published 14 Aug 2025

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