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Viral replication

Preclinical evaluation of AT-527, a novel guanosine nucleotide prodrug with potent, pan-genotypic activity against hepatitis C virus

Steven S. Good, Adel Moussa, Xiao-Jian Zhou, Keith Pietropaolo, Jean-Pierre Sommadossi

published 08 Jan 2020

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m⁶A minimally impacts the structure, dynamics, and Rev ARM binding properties of HIV-1 RRE stem IIB

Chia-Chieh Chu, Bei Liu, Raphael Plangger, Christoph Kreutz, Hashim M. Al-Hashimi

published 11 Dec 2019

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Establishment and characterization of transformed goat primary cells by expression of simian virus 40 large T antigen for orf virus propagations

Yumiko Yamada, Guan-Ru Liao, Ching-Yu Tseng, Yeu-Yang Tseng, Wei-Li Hsu

published 05 Dec 2019

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Respiratory syncytial virus exhibits differential tropism for distinct human placental cell types with Hofbauer cells acting as a permissive reservoir for infection

Vladimir Bokun, John J. Moore, Robert Moore, Carrie C. Smallcombe, Terri J. Harford, Fariba Rezaee, Frank Esper, Giovanni Piedimonte

published 02 Dec 2019

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Differential phosphorylation determines the repressor and activator potencies of GLI1 proteins and their efficiency in modulating the HPV life cycle

Alla Piirsoo, Anne Pink, Lagle Kasak, Martin Kala, Sergo Kasvandik, Mart Ustav, Marko Piirsoo

published 26 Nov 2019

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Glutathione contributes to efficient post-Golgi trafficking of incoming HPV16 genome

Shuaizhi Li, Matthew P. Bronnimann, Spencer J. Williams, Samuel K. Campos

published 19 Nov 2019

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Genotype-matched Newcastle disease virus vaccine confers improved protection against genotype XII challenge: The importance of cytoplasmic tails in viral replication and vaccine design

Ray Izquierdo-Lara, Ana Chumbe, Katherine Calderón, Manolo Fernández-Díaz, Vikram N. Vakharia

published 14 Nov 2019

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Mathematical determination of the HIV-1 matrix shell structure and its impact on the biology of HIV-1

Weijie Sun, Eduardo Reyes-Serratos, David Barilla, Joy Ramielle L. Santos, Mattéa Bujold, Sean Graves, Marcelo Marcet-Palacios

published 12 Nov 2019

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Continuous influenza virus production in a tubular bioreactor system provides stable titers and avoids the “von Magnus effect”

Felipe Tapia, Daniel Wohlfarth, Volker Sandig, Ingo Jordan, Yvonne Genzel, Udo Reichl

published 05 Nov 2019

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CCR5 receptor antagonism inhibits hepatitis C virus (HCV) replication in vitro

Jason T. Blackard, Ling Kong, Susan D. Rouster, Rebekah Karns, Paul S. Horn, Shyam Kottilil, M. Tarek Shata, Kenneth E. Sherman

published 29 Oct 2019

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Molecular characterization and In Vitro synthesis of infectious RNA of a Turnip vein-clearing virus isolated from Alliaria petiolata in Hungary

Tamás Tóth, Péter Gyula, Pál Salamon, Szilvia Kis, Anita Sós-Hegedűs, György Szittya

published 24 Oct 2019

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E2 protein is the major determinant of specificity at the human papillomavirus origin of replication

Airiin Laaneväli, Mart Ustav, Ene Ustav, Marko Piirsoo

published 23 Oct 2019

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Multiplexed editing of a begomovirus genome restricts escape mutant formation and disease development

Anirban Roy, Ying Zhai, Jessica Ortiz, Michael Neff, Bikash Mandal, Sunil Kumar Mukherjee, Hanu R. Pappu

published 23 Oct 2019

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