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Viral replication

Identification of cell lines CL-14, CL-40 and CAL-51 as suitable models for SARS-CoV-2 infection studies

Claudia Pommerenke, Ulfert Rand, Cord C. Uphoff, Stefan Nagel, Margarete Zaborski, Vivien Hauer, Maren Kaufmann, Corinna Meyer, Sabine A. Denkmann, Peggy Riese, Kathrin Eschke, Yeonsu Kim, Zeljka Macak Safranko, Ivan-Christian Kurolt, Alemka Markotic, Luka Cicin-Sain, Laura Steenpass

published 02 Aug 2021

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Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies

Lee A. Armstrong, Sven M. Lange, Virginia Dee Cesare, Stephen P. Matthews, Raja Sekhar Nirujogi, Isobel Cole, Anthony Hope, Fraser Cunningham, Rachel Toth, Rukmini Mukherjee, Denisa Bojkova, Franz Gruber, David Gray, Paul G. Wyatt, Jindrich Cinatl, Ivan Dikic, Paul Davies, Yogesh Kulathu

published 16 Jul 2021

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Effects of therapeutic vaccination on the control of SIV in rhesus macaques with variable responsiveness to antiretroviral drugs

Hillary Claire Tunggal, Paul Veness Munson, Megan Ashley O’Connor, Nika Hajari, Sandra Elizabeth Dross, Debra Bratt, James Thomas Fuller, Kenneth Bagley, Deborah Heydenburg Fuller

published 17 Jun 2021

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RNA-guided gene editing of the murine gammaherpesvirus 68 genome reduces infectious virus production

Hui-Chen Chang Foreman, Varvara Kirillov, Gabrielle Paniccia, Demetra Catalano, Trevor Andrunik, Swati Gupta, Laurie T. Krug, Yue Zhang

published 04 Jun 2021

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Avian antibodies (IgY) targeting spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibit receptor binding and viral replication

Chad Artman, Kyle D. Brumfield, Sahil Khanna, Julius Goepp

published 28 May 2021

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SARS-CoV-2: Possible recombination and emergence of potentially more virulent strains

Dania Haddad, Sumi Elsa John, Anwar Mohammad, Maha M. Hammad, Prashantha Hebbar, Arshad Channanath, Rasheeba Nizam, Sarah Al-Qabandi, Ashraf Al Madhoun, Abdullah Alshukry, Hamad Ali, Thangavel Alphonse Thanaraj, Fahd Al-Mulla

published 25 May 2021

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The combination of the NS5A and cyclophilin inhibitors results in an additive anti-HCV inhibition in humanized mice without development of resistance

Michael Bobardt, Christina M. Ramirez, Marc M. Baum, Daren Ure, Robert Foster, Philippe A. Gallay

published 20 May 2021

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Effects of osmotic pressure on the irreversible electroporation in giant lipid vesicles

Malay Kumar Sarkar, Mohammad Abu Sayem Karal, Marzuk Ahmed, Md. Kabir Ahamed, Shareef Ahammed, Sabrina Sharmin, Sayed Ul Alam Shibly

published 14 May 2021

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Identification of celastrol as a novel HIV-1 latency reversal agent by an image-based screen

Hongbing Liu, Pei-Wen Hu, Julien Dubrulle, Fabio Stossi, Bryan C. Nikolai, Michael A. Mancini, Andrew P. Rice

published 29 Apr 2021

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Clinical utility of hepatitis C virus core antigen (HCVcAg) assay to identify active HCV infection in hemodialysis and renal transplant patients

Suresh Ponnuvel, Gnanadurai John Fletcher, Raghavendran Anantharam, Santosh Varughese, Vinoy George David, Priya Abraham

published 22 Apr 2021

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Iron enhances the binding rates and translational efficiency of iron responsive elements (IREs) mRNA with initiation factor eIF4F

Mateen A. Khan, Artem V. Domashevskiy

published 21 Apr 2021

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Characteristics and expression profiles of circRNAs during abdominal adipose tissue development in Chinese Gushi chickens

Wenjiao Jin, Yinli Zhao, Bin Zhai, Yuanfang Li, Shengxin Fan, Pengtao Yuan, Guirong Sun, Ruirui Jiang, Yanbin Wang, Xiaojun Liu, Yadong Tian, Xiangtao Kang, Guoxi Li

published 15 Apr 2021

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The synthetic opioid fentanyl enhances viral replication in vitro

Ling Kong, Rebekah Karns, Mohamed Tarek M. Shata, Jennifer L. Brown, Michael S. Lyons, Kenneth E. Sherman, Jason T. Blackard

published 14 Apr 2021

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