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Viral replication

The interaction of dengue virus capsid protein with negatively charged interfaces drives the in vitro assembly of nucleocapsid-like particles

Nathane C. Mebus-Antunes, Wellington S. Ferreira, Glauce M. Barbosa, Thais C. Neves-Martins, Gilberto Weissmuller, Fabio C. L. Almeida, Andrea T. Da Poian

published 01 Mar 2022

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Optimizing environmental safety and cell-killing potential of oncolytic Newcastle Disease virus with modifications of the V, F and HN genes

J. Fréderique de Graaf, Stefan van Nieuwkoop, Theo Bestebroer, Daphne Groeneveld, Casper H. J. van Eijck, Ron A. M. Fouchier, Bernadette G. van den Hoogen

published 09 Feb 2022

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Antibodies directed towards neuraminidase restrict influenza virus replication in primary human bronchial epithelial cells

Anouk Smet, Joao Paulo Portela Catani, Tine Ysenbaert, Amanda Gonçalves, Harry Kleanthous, Thorsten U. Vogel, Xavier Saelens, Emma R. Job

published 31 Jan 2022

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A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model

Dorjbal Dorjsuren, Richard T. Eastman, Min Jae Song, Adam Yasgar, Yuchi Chen, Kapil Bharti, Alexey V. Zakharov, Ajit Jadhav, Marc Ferrer, Pei-Yong Shi, Anton Simeonov

published 18 Jan 2022

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Adenylate kinase 1 overexpression increases locomotor activity in medaka fish

Michiyo Maruyama, Yuko Furukawa, Masato Kinoshita, Atsushi Mukaiyama, Shuji Akiyama, Takashi Yoshimura

published 04 Jan 2022

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Evaluation of the efficacy of LAMP-based SARS-CoV-2 detection with simple RNA extraction from nasopharyngeal swabs: A prospective observational study

Masaki Karino, Mizuki Harada, Chihiro Yamada, Kyoko Fukuoka, Megumi Sugo, Hiroyuki Hanada, Daisaku Masuda, Shingo Adachi, Shota Nakao, Masayuki Seki, Masaya Yamato, Shizuya Yamashita, Toru Takano

published 14 Dec 2021

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¹H, ¹³C and ¹⁵N resonance assignment of the SARS-CoV-2 full-length nsp1 protein and its mutants reveals its unique secondary structure features in solution

Tatiana Agback, Francisco Dominguez, Ilya Frolov, Elena I. Frolova, Peter Agback

published 07 Dec 2021

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Breadth of CD8 T-cell mediated inhibition of replication of diverse HIV-1 transmitted-founder isolates correlates with the breadth of recognition within a comprehensive HIV-1 Gag, Nef, Env and Pol potential T-cell epitope (PTE) peptide set

Peter Hayes, Natalia Fernandez, Christina Ochsenbauer, Jama Dalel, Jonathan Hare, Deborah King, Lucas Black, Claire Streatfield, Vanaja Kakarla, Gladys Macharia, Julia Makinde, Matt Price, Eric Hunter, The IAVI protocol C investigators , Jill Gilmour

published 17 Nov 2021

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Drug repositioning of Clopidogrel or Triamterene to inhibit influenza virus replication in vitro

Nichole Orr-Burks, Jackelyn Murray, Kyle V. Todd, Abhijeet Bakre, Ralph A. Tripp

published 29 Oct 2021

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Leveraging publicly available coronavirus data to identify new therapeutic targets for COVID-19

Stacy L. Sell, Donald S. Prough, Harris A. Weisz, Steve G. Widen, Helen L. Hellmich

published 29 Sep 2021

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Diagnostic accuracy and acceptability of molecular diagnosis of COVID-19 on saliva samples relative to nasopharyngeal swabs in tropical hospital and extra-hospital contexts: The COVISAL study

Mathieu Nacher, Mayka Mergeay-Fabre, Denis Blanchet, Orelie Benois, Tristan Pozl, Pauline Mesphoule, Vincent Sainte-Rose, Véronique Vialette, Bruno Toulet, Aurélie Moua, Mona Saout, Stéphane Simon, Manon Guidarelli, Muriel Galindo, Barbara Biche, William Faurous, Laurie Chaizemartin, Aniza Fahrasmane, Devi Rochemont, Fode Diop, Moussa Niang, Jean Pujo, Nicolas Vignier, Dominique Dotou, Astrid Vabret, Magalie Demar

published 13 Sep 2021

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Direct detection of SARS-CoV-2 antisense and sense genomic RNA in human saliva by semi-autonomous fluorescence in situ hybridization: A proxy for contagiousness?

Gijsbert J. Jansen, Marit Wiersma, Willem J. B. van Wamel, Inge D. Wijnberg

published 17 Aug 2021

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Evaluation of TTV replication as a biomarker of immune checkpoint inhibitors efficacy in melanoma patients

Rémi Pescarmona, William Mouton, Thierry Walzer, Stéphane Dalle, Anaïs Eberhardt, Karen Brengel-Pesce, Marine Villard, Christine Lombard, Sophie Trouillet-Assant, Sébastien Viel

published 09 Aug 2021

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