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Transition state

The Role of Protein Denaturation Energetics and Molecular Chaperones in the Aggregation and Mistargeting of Mutants Causing Primary Hyperoxaluria Type I

Noel Mesa-Torres, Israel Fabelo-Rosa, Debora Riverol, Cristina Yunta, Armando Albert, Eduardo Salido, Angel L. Pey

published 27 Aug 2013

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Unique Kinase Catalytic Mechanism of AceK with a Single Magnesium Ion

Quanjie Li, Jimin Zheng, Hongwei Tan, Xichen Li, Guangju Chen, Zongchao Jia

published 19 Aug 2013

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Geometric Attributes of Retaining Glycosyltransferase Enzymes Favor an Orthogonal Mechanism

Brock Schuman, Stephen V. Evans, Thomas M. Fyles

published 01 Aug 2013

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Comparison and Analysis of Zinc and Cobalt-Based Systems as Catalytic Entities for the Hydration of Carbon Dioxide

Edmond Y. Lau, Sergio E. Wong, Sarah E. Baker, Jane P. Bearinger, Lucas Koziol, Carlos A. Valdez, Joseph H. Satcher Jr, Roger D. Aines, Felice C. Lightstone

published 20 Jun 2013

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Crystal Structures of Carbamate Kinase from Giardia lamblia Bound with Citric Acid and AMP-PNP

Kap Lim, Liudmila Kulakova, Andrey Galkin, Osnat Herzberg

published 20 May 2013

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Conserved N-Terminal Negative Charges Support Optimally Efficient N-type Inactivation of Kv1 Channels

Alison Prince, Paul J. Pfaffinger

published 24 Apr 2013

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Mapping Enzymatic Catalysis Using the Effective Fragment Molecular Orbital Method: Towards all ab initio Biochemistry

Casper Steinmann, Dmitri G. Fedorov, Jan H. Jensen

published 12 Apr 2013

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Global Conformational Selection and Local Induced Fit for the Recognition between Intrinsic Disordered p53 and CBP

Qingfen Yu, Wei Ye, Wei Wang, Hai-Feng Chen

published 26 Mar 2013

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The Roles of Helix I and Strand 5A in the Folding, Function and Misfolding of α₁-Antitrypsin

Anja S. Knaupp, Shani Keleher, Li Yang, Weiwen Dai, Stephen P. Bottomley, Mary C. Pearce

published 29 Jan 2013

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A Computational Methodology to Screen Activities of Enzyme Variants

Martin R. Hediger, Luca De Vico, Allan Svendsen, Werner Besenmatter, Jan H. Jensen

published 17 Dec 2012

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Multi-State Proteins: Approach Allowing Experimental Determination of the Formation Order of Structure Elements in the Green Fluorescent Protein

Tatiana N. Melnik, Tatiana V. Povarnitsyna, Anatoly S. Glukhov, Bogdan S. Melnik

published 14 Nov 2012

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Protein Dynamics Governed by Interfaces of High Polarity and Low Packing Density

Vladimir Espinosa Angarica, Javier Sancho

published 26 Oct 2012

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pKa Modulation of the Acid/Base Catalyst within GH32 and GH68: A Role in Substrate/Inhibitor Specificity?

Shuguang Yuan, Katrien Le Roy, Tom Venken, Willem Lammens, Wim Van den Ende, Marc De Maeyer

published 25 May 2012

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