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Toxicity

Overexpression of the translocon accessory protein YajC alleviates toxicity of the endogenous pore-forming toxin LdrA in Escherichia coli

Yuto Nakamura, Yoshihiro Yamaguchi

Evaluation of imputation strategies for multi-centre studies: Application to a large clinical pathology dataset

Lucy Grigoroff, Reika Masuda, [ ... ], Julien Wist

Skeletal muscle index, grip strength, and physical performance as predictors of severe chemotherapy toxicity among older adults with malignancy

Efthymios Papadopoulos, Dmitry Rozenberg, [ ... ], Shabbir M. H. Alibhai

Antitumor and cytotoxic activities of endophytic Enterobacter hormaechei derived secondary metabolites: In-vitro and In-silico study

Muddasir Khan, Sumera Afzal Khan, [ ... ], Muhammad Hamayun

Computational identification of novel SIRT4 inhibitors for diabetic nephropathy using pharmacophore modeling, molecular simulations, and DFT calculations

Wenxiang He, Jianwu Chen

crm12comb: Phase I/II adaptive design for drug combinations based on CRM design through R

Junying Wang, Song Wu, Jie Yang

A systematic comparison of patient information leaflets from local and multinational pharmaceutical companies: Assessing content quality and completeness

Abdulaziz Ibrahim Alzarea, Azfar Athar Ishaqui, [ ... ], Omar Awad Alsaidan

GCMS profiling of bioactive phytocompounds from Curculigo orchiodes Gaertn. root extract and evaluation of antioxidant, and antidiabetic activities: A computational drug development approach

Imran Mahmud, Md. Khalid Saifullah, [ ... ], Nripendra Nath Biswas

Design, synthesis, and biological evaluation of phenylisoxazole-based histone deacetylase inhibitors

Xiaofei Qin, Meng Han, [ ... ], Dong Yan

A Fragmentation behavior-guided UHPLC-Q-Orbitrap HRMS method for the quantitative analysis of 26 perfluoroalkyl substances and their alternatives in water

Guojian Shao, Tao Liu, [ ... ], Ye Wang

From sea to cure: Discovery of marine-derived therapeutics against Fusarium solani in shrimps for enhancing aquaculture sustainability

Abdullah Al Siam, Avijit Kumer Paul, [ ... ], Shyamal Kumar Paul

In vitro toxicity assessment of uranium particulates on different human lung epithelial cell models

Shepard C. Moore, Laura M. Lilley, [ ... ], Jennifer Foster Harris

Hematological toxicity of anti-tumor antibody-drug conjugates: A retrospective pharmacovigilance study using the FDA adverse event reporting system

Mei Rao, Lihua Wu, [ ... ], Chunmei Chen

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