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Toxicity

Unraveling the therapeutic potential of Elaeagnus angustifolia extract on triple-negative breast cancer (TNBC): An investigation using zebrafish model

Haya Abuhijleh, Zain Zakria, Hiba Bawadi, Ayat Hammad, Ala-Eddin Al Moustafa, Abdullah Shaito, Maha Al-Asmakh

published 06 Mar 2026

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Clinical outcomes with lower versus conventional dose polymyxin B regimens in dialysis dependent and non-dialysis patients with gram-negative sepsis: A real-world propensity-score matched cohort study

Asha K. Rajan, Vishal Shanbhag, Vijayanarayana Kunhikatta, Ravindra Prabhu Attur, Beven Nelson, Varun Kumar S. G, Souvik Chaudhuri, Girish Thunga

published 04 Mar 2026

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Cheminformatics-driven discovery of natural isoquinoline alkaloid inhibitors of Beta-secretase I for Alzheimer’s management

Iqra Ahmad, Sara Waheed, Bader S. Alotaibi, Sumra Wajid Abbasi, Muhammad Umer Khan, Faiz Ur Rahman, Hanna Dib, Khaled Fahmi Fawy, Umar Nishan, Abid Ali, Aqal Zaman, Mohibullah Shah

published 02 Mar 2026

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A phase I clinical trial to evaluate the tolerability and safety of an allogeneic iPSC-derived iNKT cell and α-GalCer-pulsed autologous DC combination therapy for patients with recurrent and advanced head and neck cancer: A study protocol

Tomoya Kurokawa, Tomohisa Iinuma, Haruna Ebisu, Tomoha Yanagidaira, Yosuke Inaba, Tadami Fujiwara, Yoko Hattori, Tominaga Fukazawa, Takahiro Aoki, Haruhiko Koseki, Hideki Hanaoka, Toyoyuki Hanazawa, Shinichiro Motohashi

published 26 Feb 2026

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Irritancy and spatial repellency efficacy of repellent-treated fabrics against Aedes aegypti (L.) (Diptera: Culicidae) in an excito-repellency system

Alex Ahebwa, Jeffrey Hii, Theerachart Leepasert, Jirod Nararak, Monthathip Kongmee, Theeraphap Chareonviriyaphap

published 26 Feb 2026

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Mechanistic insights into triclosan-induced hepatotoxicity: A network toxicology and molecular docking approach

Fuzhi Liu, Yanyan Zhao, Dandan Zhu, Jingwen Wang, Zhaocheng Zhuang, Yangjia Chen, Yuan Su, Zhuote Tu

published 25 Feb 2026

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Hepatic arterial infusion chemotherapy (HAlC) versus sorafenib for hepatocellular carcinoma (HCC) in Barcelona Clinic Liver Cancer (BCLC) B/C: A systematic review and meta-analysis

Zhengqiang Chen, Yaotian Fan, Yuting Luo, Xiwen Ye, Zhen You

published 18 Feb 2026

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Study protocol for a multicenter phase II prospective externally controlled non-inferiority trial of hypofractionated re-irradiation in patients with recurrent high-grade glioma (RISinG)

A. M. de Jong, A. T. J. van der Boog, C. C. B. Post, F. Cialdella, D. B. P. Eekers, J. Hendrikse, M. C. A. Kramer, F. J. Lagerwaard, M. van der Meulen, M. E. P. Philippens, P. A. Robe, T. Rozema, F. Y. F. L. de Vos, J. Vos-Westerman, H. L. van der Weide, G. Wester, J. Zindler, T. J. Snijders, J. J. C. Verhoeff

published 09 Feb 2026

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RAF1 as a standalone therapeutic target in KRAS-driven lung adenocarcinoma: No added efficacy from co-targeting ARAF, EGFR, or DDR1

Laura de-la-Puente-Ovejero, Ana Fernández-Rodríguez, Sarah Francoz, Gonzalo Aizpurua, Lucía Lomba-Riego, Matthias Drosten, Carmen Guerra, Mónica Musteanu, Mariano Barbacid, Sara García-Alonso

published 06 Feb 2026

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Simultaneous triclosan degradation and nitrate reduction by a UV/Sulfite/Phenol process based on sulfite radical mechanism: dechlorination, mineralization, and bioassessment

Hossein Faraji, Mehdi Salari, Forough Riahimanesh, Hadi Rahimzadeh, Behrouz Akbari-adergani, Asieh khalilpour, Nasim Naeeji, Fatemeh Asgharzadeh

published 06 Feb 2026

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Discovery of a novel Keap1 inhibitor for neurodegeneration through virtual screening and molecular dynamics simulations

Md. Mazedul Hasan, Md. Shaki Mostaid, Asim Kumar Bepari, Hasan Mahmud Reza, Murad Hossain

published 02 Feb 2026

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Physiological responses of Cucurbita pepo seeds to cadmium and copper stress: Differential impacts on reserve mobilization, metabolic efficiency, and growth

Smail Acila, Nora Allioui, Samir Derouiche

published 30 Jan 2026

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Uralenol, Glycyrol, and Abyssinone II as potent inhibitors of fibroblast growth factor receptor 2 from anti-cancer plants: A deep learning and molecular dynamics approach

Alomgir Hossain, Md. Sanowar Hossan, Md. Shahanur Prodhan, Md. Nahid Hasan Joy, Muntasir Rahman Siam, Md. Ekhtiar Rahman, Mohammad Nurul Matin

published 30 Jan 2026

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