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Toxicity

Hepatic transcriptomic responses in gravid and non-gravid rats exposed to HFPO-DA: Analyses to inform the role of maternal effects in neonatal toxicity

Melissa M. Heintz, Chad M. Thompson, Jeffrey C. Wolf, John M. Rogers, Laurie C. Haws

published 01 Apr 2026

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Predicted antiviral potential of phytochemicals prolific in Cleistanthus bracteosus Jabl. and essential oils of Artemisia scoparia and Thuja orientalis against Nipah virus and Human metapneumovirus: An AI-driven in-silico study

Mackingsley Kushan Dassanayake, Teng-Jin Khoo, Chien Hwa Chong, Mohammed Tahir Ansari, Patrick Di Martino, Fernando Berton Zanchi, Adam Figiel, Antoni Szumny, Omar Ashraf Elfar, Christophe Wiart, Rachael Symonds

published 31 Mar 2026

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Unraveling the toxicological impact of Bisphenol A exposure on dermatomyositis: An integration of network toxicology and machine learning approaches

Lili Cheng, Zhongfu Tang, Ming Li, Chuanbing Huang

published 30 Mar 2026

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Plasma heme pool compartmentalization is linked to pathophysiology in Sickle Cell Disease

Moritz Saxenhofer, Daniel Couto, Sandra Mena Perez, Marlies Illi, Justine Brodard, Linet Njue, Ioannis Chanias, Cesare Medri, Gerasimos Tsilimidos, Nicole Hadorn, Christelle Chirlias, Ana-Patricia Batista Mesquita, Lucas Veuthey, Anna Schnell, Stefanie Graeter, Gregory J. Kato, Jacqueline Adam, Ramona Merki, Emmanuel Levrat, Kaveh Samii, Mila Keiser, Kathrin Susann Bieri, Alan G. Haynes, Anne Angelillo-Scherrer, Lorenzo Alberio, Francesco Grandoni, Mathilde Gavillet, Thomas Gentinetta, Alicia Rovó, Alexander Schaub

published 26 Mar 2026

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Identification of polyphenols as novel neuropilin-1 cendR pocket inhibitors to block SARS-CoV-2 entry and enhance variant resistance

Farid Ataya, Abir Alamro, Amani Alghamdi, Dalia Fouad

published 23 Mar 2026

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Elucidating the potential carcinogenic molecular mechanisms of parabens in head and neck squamous cell carcinoma through network toxicology and molecular docking

Lei Zhao, Jianwang Yang, Tao Liu, Huan Cao, Miaomiao Yu, Baoshan Wang

published 23 Mar 2026

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Nonmyeloablative pentostatin-cyclophosphamide preconditioning improves rates of engraftment in adults undergoing haploidentical HCT for sickle cell disease

Emily Limerick, Matthew Hsieh, Jackie Queen, Mary Lacy Grecco, Julia Varga, Jennifer Brooks, Wynona Coles, Neal Jeffries, Courtney D. Fitzhugh

published 23 Mar 2026

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Food and feed safety of a novel Vip3C insecticidal protein derived from Paenibacillus spp. for protection of crop plants against key Lepidopteran pests

Lucas J. McKinnon, Rong Wang, Cunxi Wang, Scott Saracco, Colton Kessenich, Virginia M. Johnson, Jennifer Calcaterra, Gregory Frierdich, Eric Bretsnyder, Luting Fang, Bingyao Li, Tianbo Xu

published 18 Mar 2026

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Functional effects of extracellular vesicles altered by a per- and polyfluoroalkyl substance mixture: In vitro liver cytotoxicity and proteomic expression alterations

Celeste K. Carberry, Angie L. Mordant, Christine A. Mills, Hadley Hartwell, Victoria F. Carberry, Lauren Simendinger, Elise Hickman, Laura E. Herring, Julia E. Rager

published 18 Mar 2026

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Biological evaluation of amidine derivatives: In vitro cytotoxicity and cellular antioxidant capacity

Maria M. Pérez-Madrigal, Luis J. del Valle, Sara Armas Felipe, Cristina del Mar García Martín, José Ignacio Hernández García, César Saldías, Matías Funes, Carlos Alemán, MG Finn, David Díaz Díaz

published 13 Mar 2026

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Dosimetric comparison study of ultrahypofractionated photon versus proton treatment plans in post breast-conserving surgery breast cancer

Kitwadee Saksornchai, Tanawat Tawonwong, Puntiwa Oonsiri, Mananchaya Vimolnoch, Thanaporn Sarsitthithum, Chawalit Lertbutsayanukul, Chonnipa Nantavithya

published 11 Mar 2026

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Potentially unsafe doses of local anesthetics in axillary brachial plexus block: A single-center retrospective cohort study

Mélanie Suppan, Caroline Flora Samer, Georges Louis Savoldelli

published 11 Mar 2026

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Exploring potential phytocompounds from black cumin as drug molecules against SARS-CoV-2 infections through bioinformatics analysis

Md. Ahad Ali, Humaira Sheikh, Md. Selim Reza, Tripti Rani Paul, Tasfia Noor, Neeraj Kumar, Mashooq Ahmad Bhat, Md. Nurul Haque Mollah

published 11 Mar 2026

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