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Toxicity

Activation of p38MAPK Contributes to Expanded Polyglutamine-Induced Cytotoxicity

Maria Tsirigotis, R. Mitchell Baldwin, Matthew Y. Tang, Ian A. J. Lorimer, Douglas A. Gray

published 07 May 2008

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Sequence Effect of Self-Assembling Peptides on the Complexation and In Vitro Delivery of the Hydrophobic Anticancer Drug Ellipticine

Shan Yu Fung, Hong Yang, P. Chen

published 09 Apr 2008

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DJ-1 Modulates α-Synuclein Aggregation State in a Cellular Model of Oxidative Stress: Relevance for Parkinson's Disease and Involvement of HSP70

Sara Batelli, Diego Albani, Raffaela Rametta, Letizia Polito, Francesca Prato, Marzia Pesaresi, Alessandro Negro, Gianluigi Forloni

published 02 Apr 2008

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Formation of Toxic Oligomeric α-Synuclein Species in Living Cells

Tiago Fleming Outeiro, Preeti Putcha, Julie E. Tetzlaff, Robert Spoelgen, Mirjam Koker, Filipe Carvalho, Bradley T. Hyman, Pamela J. McLean

published 02 Apr 2008

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A Naturally Occurring Plant Cysteine Protease Possesses Remarkable Toxicity against Insect Pests and Synergizes Bacillus thuringiensis Toxin

Srinidi Mohan, Peter W. K. Ma, W. Paul Williams, Dawn S. Luthe

published 12 Mar 2008

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Aβ42 Mutants with Different Aggregation Profiles Induce Distinct Pathologies in Drosophila

Koichi Iijima, Hsueh-Cheng Chiang, Stephen A. Hearn, Inessa Hakker, Anthony Gatt, Christopher Shenton, Linda Granger, Amy Leung, Kanae Iijima-Ando, Yi Zhong

published 27 Feb 2008

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Genetic and Chemical Modifiers of a CUG Toxicity Model in Drosophila

Amparo Garcia-Lopez, Lidon Monferrer, Irma Garcia-Alcover, Marta Vicente-Crespo, M. Carmen Alvarez-Abril, Ruben D. Artero

published 13 Feb 2008

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Repeat Length and RNA Expression Level Are Not Primary Determinants in CUG Expansion Toxicity in Drosophila Models

Gwenn Le Mée, Nader Ezzeddine, Michèle Capri, Ounissa Aït-Ahmed

published 23 Jan 2008

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Ataxin-1 Fusion Partners Alter PolyQ Lethality and Aggregation

Tina Rich, Archana Varadaraj

published 10 Oct 2007

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A New Classification System for the Actions of IRS Chemicals Traditionally Used For Malaria Control

John P. Grieco, Nicole L. Achee, Theeraphap Chareonviriyaphap, Wannapa Suwonkerd, Kamal Chauhan, Michael R. Sardelis, Donald R. Roberts

published 08 Aug 2007

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Identification of Potential Therapeutic Drugs for Huntington's Disease using Caenorhabditis elegans

Cindy Voisine, Hemant Varma, Nicola Walker, Emily A. Bates, Brent R. Stockwell, Anne C. Hart

published 06 Jun 2007

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Bacterial Toxicity of Potassium Tellurite: Unveiling an Ancient Enigma

José M. Pérez, Iván L. Calderón, Felipe A. Arenas, Derie E. Fuentes, Gonzalo A. Pradenas, Eugenia L. Fuentes, Juan M. Sandoval, Miguel E. Castro, Alex O. Elías, Claudio C. Vásquez

published 14 Feb 2007

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Non-Metabolic Membrane Tubulation and Permeability Induced by Bioactive Peptides

Antonin Lamazière, Fabienne Burlina, Claude Wolf, Gérard Chassaing, Germain Trugnan, Jesus Ayala-Sanmartin

published 14 Feb 2007

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