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Toxicity

r84, a Novel Therapeutic Antibody against Mouse and Human VEGF with Potent Anti-Tumor Activity and Limited Toxicity Induction

Laura A. Sullivan, Juliet G. Carbon, Christina L. Roland, Jason E. Toombs, Mari Nyquist-Andersen, Anita Kavlie, Kyle Schlunegger, James A. Richardson, Rolf A. Brekken

published 06 Aug 2010

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Paradoxical Role of Prion Protein Aggregates in Redox-Iron Induced Toxicity

Dola Das, Xiu Luo, Ajay Singh, Yaping Gu, Soumya Ghosh, Chinmay K. Mukhopadhyay, Shu G. Chen, Man-Sun Sy, Qingzhong Kong, Neena Singh

published 06 Jul 2010

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The Werner Syndrome Protein Suppresses Telomeric Instability Caused by Chromium (VI) Induced DNA Replication Stress

Fu-Jun Liu, Aaron Barchowsky, Patricia L. Opresko

published 16 Jun 2010

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Rates and Reasons for Early Change of First HAART in HIV-1-Infected Patients in 7 Sites throughout the Caribbean and Latin America

Carina Cesar, Bryan E. Shepherd, Alejandro J. Krolewiecki, Valeria I. Fink, Mauro Schechter, Suely H. Tuboi, Marcelo Wolff, Jean W. Pape, Paul Leger, Denis Padgett, Juan Sierra Madero, Eduardo Gotuzzo, Omar Sued, Catherine C. McGowan, Daniel R. Masys, Pedro E. Cahn, for The Caribbean , Central and South America Network for HIV Research (CCASAnet) Collaboration , of the International Epidemiologic Databases to Evaluate AIDS (IeDEA) Program

published 01 Jun 2010

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Toxicology and Drug Delivery by Cucurbit[n]uril Type Molecular Containers

Gaya Hettiarachchi, Duc Nguyen, Jing Wu, Derick Lucas, Da Ma, Lyle Isaacs, Volker Briken

published 06 May 2010

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Dynamic Zebrafish Interactome Reveals Transcriptional Mechanisms of Dioxin Toxicity

Andrey Alexeyenko, Deena M. Wassenberg, Edward K. Lobenhofer, Jerry Yen, Elwood Linney, Erik L. L. Sonnhammer, Joel N. Meyer

published 05 May 2010

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A Randomized, Controlled, Trial of Short Cycle Intermittent Compared to Continuous Antiretroviral Therapy for the Treatment of HIV Infection in Uganda

Steven J. Reynolds, Cissy Kityo, Claire W. Hallahan, Geoffrey Kabuye, Diana Atwiine, Frank Mbamanya, Francis Ssali, Robin Dewar, Marybeth Daucher, Richard T. Davey Jr, Peter Mugyenyi, Anthony S. Fauci, Thomas C. Quinn, Mark R. Dybul

published 22 Apr 2010

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Metal-Free ALS Variants of Dimeric Human Cu,Zn-Superoxide Dismutase Have Enhanced Populations of Monomeric Species

Anna-Karin E. Svensson, Osman Bilsel, Can Kayatekin, Jessica A. Adefusika, Jill A. Zitzewitz, C. Robert Matthews

published 09 Apr 2010

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Stress-Induced Sphingolipid Signaling: Role of Type-2 Neutral Sphingomyelinase in Murine Cell Apoptosis and Proliferation

Raphael Devillard, Sylvain Galvani, Jean-Claude Thiers, Jean-Louis Guenet, Yusuf Hannun, Jacek Bielawski, Anne Nègre-Salvayre, Robert Salvayre, Nathalie Augé

published 23 Mar 2010

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Induction of Autophagy by Cystatin C: A Mechanism That Protects Murine Primary Cortical Neurons and Neuronal Cell Lines

Belen Tizon, Susmita Sahoo, Haung Yu, Sebastien Gauthier, Asok R. Kumar, Panaiyur Mohan, Matthew Figliola, Monika Pawlik, Anders Grubb, Yasuo Uchiyama, Urmi Bandyopadhyay, Ana Maria Cuervo, Ralph A. Nixon, Efrat Levy

published 23 Mar 2010

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pH-Dependent Metal Ion Toxicity Influences the Antibacterial Activity of Two Natural Mineral Mixtures

Tanya M. Cunningham, Jennifer L. Koehl, Jack S. Summers, Shelley E. Haydel

published 01 Mar 2010

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In Vitro and Ex Vivo Testing of Tenofovir Shows It Is Effective As an HIV-1 Microbicide

Lisa C. Rohan, Bernard J. Moncla, Ratiya Pamela Kunjara Na Ayudhya, Marilyn Cost, Yunda Huang, Fang Gai, Nicole Billitto, J. D. Lynam, Kara Pryke, Phillip Graebing, Nicole Hopkins, James F. Rooney, David Friend, Charlene S. Dezzutti

published 19 Feb 2010

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Potent Anti-Inflammatory Activity of Novel Microtubule-Modulating Brominated Noscapine Analogs

Susu Zughaier, Prasanthi Karna, David Stephens, Ritu Aneja

published 11 Feb 2010

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