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Toxicity

A Novel Statistical Algorithm for Gene Expression Analysis Helps Differentiate Pregnane X Receptor-Dependent and Independent Mechanisms of Toxicity

M. Ann Mongan, Robert T. Dunn II, [ ... ], Hisham K. Hamadeh

Uptake of Aggregating Transthyretin by Fat Body in a Drosophila Model for TTR-Associated Amyloidosis

Malgorzata Pokrzywa, Ingrid Dacklin, [ ... ], Rafael Cantera

Acetaminophen Induces Apoptosis in Rat Cortical Neurons

Inmaculada Posadas, Pablo Santos, [ ... ], Valentín Ceña

Decreased Level of Nurr1 in Heterozygous Young Adult Mice Leads to Exacerbated Acute and Long-Term Toxicity after Repeated Methamphetamine Exposure

Yu Luo, Yun Wang, [ ... ], Barry Hoffer

The Cytosolic Tail of the Golgi Apyrase Ynd1 Mediates E4orf4-Induced Toxicity in Saccharomyces cerevisiae

Karin Mittelman, Keren Ziv, Tsofnat Maoz, Tamar Kleinberger

Metallothioneins Are Required for Formation of Cross-Adaptation Response to Neurobehavioral Toxicity from Lead and Mercury Exposure in Nematodes

Boping Ye, Qi Rui, Qiuli Wu, Dayong Wang

Dioxin Toxicity In Vivo Results from an Increase in the Dioxin-Independent Transcriptional Activity of the Aryl Hydrocarbon Receptor

Miguel Angel Céspedes, Maximo Ibo Galindo, Juan Pablo Couso

Synphilin-1 Enhances α-Synuclein Aggregation in Yeast and Contributes to Cellular Stress and Cell Death in a Sir2-Dependent Manner

Sabrina Büttner, Charlotte Delay, [ ... ], Joris Winderickx

Splice Isoforms of the Polyglutamine Disease Protein Ataxin-3 Exhibit Similar Enzymatic yet Different Aggregation Properties

Ginny Marie Harris, Katerina Dodelzon, [ ... ], Henry L. Paulson

Cocaine Potentiates Astrocyte Toxicity Mediated by Human Immunodeficiency Virus (HIV-1) Protein gp120

Yanjing Yang, Honghong Yao, [ ... ], Shilpa Buch

Genipin-Induced Inhibition of Uncoupling Protein-2 Sensitizes Drug-Resistant Cancer Cells to Cytotoxic Agents

Ryan J. Mailloux, Cyril Nii-Klu Adjeitey, Mary-Ellen Harper

Novel HTS Strategy Identifies TRAIL-Sensitizing Compounds Acting Specifically Through the Caspase-8 Apoptotic Axis

Darren Finlay, Robyn D. Richardson, [ ... ], Kristiina Vuori

Yokukansan Inhibits Neuronal Death during ER Stress by Regulating the Unfolded Protein Response

Toru Hiratsuka, Shinsuke Matsuzaki, [ ... ], Masaya Tohyama

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