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Toxicity

Behavioral and genetic analysis of the effects of the psychedelic 2,5-dimethoxy-4-iodoamphetamine (DOI) in C. elegans

Amanda M. White, Adele D. Bauer, Serge Faumont, Shawn R. Lockery

published 26 Aug 2025

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A real-world pharmacovigilance analysis of ALK inhibitor-associated pleural and pericardial effusion using the FDA Adverse Events Reporting System (FAERS) database from 2013 to 2024

Connor Frey

published 19 Aug 2025

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HPLC-MS profiling and protective potential of the defatted aqueous methanol extract of two Syzygium species against cadmium chloride-induced nephrotoxicity in rats

Fatma A. Moharram, Sahar S. Salem, Samah Shabana, Elsayed K. El-Sayed, Shimaa K. Mohamed, Mohamed A. Khattab, Kuei-Hung Lai, Asmaa A. Ahmed, Heba E. Elsayed

published 14 Aug 2025

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Computationally accelerated identification of P-glycoprotein inhibitors

Lauren A. McCormick, James W. McCormick, Chanyang Park, Courtney A. Follit, John G. Wise, Pia D. Vogel

published 13 Aug 2025

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Evaluation of acute ocular toxicity after definitive-intent radiation therapy in canine sinonasal tumors

Jonas Brückner, Carla Rohrer Bley, Antonella Rampazzo, Sergejs Unterkirhers, Simon Pot, Valeria Meier

published 11 Aug 2025

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Prenatal developmental toxicity of Urtica simensis essential oil in rat embryos and rat fetuses

Bickes Wube, Kaleab Asres, Samuel Woldekidan, Abiy Abebe, Yonas Girma, Girma Seyoum

published 31 Jul 2025

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TunR2, a novel mode-of-action tunicamycin-type antibiotic: Pharmacokinetics in C57BL/6 mouse and Holstein cattle

Maria A. Colombatti Olivieri, Eric D. Cassmann, Michael A. Jackson, Neil P. J. Price, John P. Bannantine

published 23 Jul 2025

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Assessment of tannery effluents quality treated by electrocoagulation and ozonation: Physicochemical and ecotoxicological characterization

Edwar Aguilar-Ascón, Liliana Marrufo-Saldaña, Julio Barra-Hinojosa, Robert Buleje-del-Carpio

published 22 Jul 2025

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Targeted modulation of MMP9 and GRP78 via molecular interaction and in silico profiling of Curcuma caesia rhizome metabolites: A computational drug discovery approach for cancer therapy

Mahek Desai, Soham Bhattacharya, Saurabhkumar Mehta, Kaushiki Joshi, Mitesh B. Solanki, Trilok Akhani, Iva Viehmannová, Eloy Fernández Cusimamani

published 18 Jul 2025

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Evaluation of Sub-acute toxicity and safety profile of Charmagaz seed oil in rats

Anum Adil, Saira Saeed Khan, Sadaf Naeem, Ali Alqahtani, Taha Alqahtani, Ali Asgher Shuja, Anosh Tahir

published 11 Jul 2025

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Biweekly CAPOX versus triweekly CAPOX in the adjuvant therapy of post-surgery CRC: A randomized controlled trial

Hangyu Zhang, Danyang Wang, Zhou Tong, Tao Xiang, Xudong Zhu, Lulu Liu, Yi Zheng, Peng Zhao, Weijia Fang, Wenbin Chen

published 11 Jul 2025

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Exploration of effective pharmacological inhibitors for NS5 protein through computational approach: A strategy to combat the neglected Kyasanur forest disease virus

Sharanappa Achappa, Nayef Abdulaziz Aldabaan, Mohammed Alasmary, Ibrahim Ahmed Shaikh, Mater H. Mahnashi, Shivalingsarj V. Desai, Uday M. Muddapur, Aejaz Abdullatif Khan, Basheerahmed Abdulaziz Mannasaheb

published 10 Jul 2025

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Diversity of Aβ aggregates produced in a gut-based Drosophila model of Alzheimer’s disease

Greta Elovsson, Therése Klingstedt, K. Peter R. Nilsson, Ann-Christin Brorsson

published 08 Jul 2025

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