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Toxicity

Phytochemicals from Astragalus zederbaueri as Acetylcholinesterase Inhibitors for Alzheimer’s Therapy

Saman Asghar, Muhammad Umer Khan, Talha Jawaid, Raima Rehman, Abeeha Shafi, Abdullah R. Alzahrani, Zia Ur Rehman, Abida Khan

published 10 Apr 2026

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Development and evaluation of a multimodal feature-based predictive model for radiotherapy-induced oral mucositis in nasopharyngeal carcinoma

Ling Li, Linke Li, Ruifeng Guo, Shiting Fang, Ke Wang, Ge Yuan, Danxian Jiang, Jing Huang

published 09 Apr 2026

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Antimicrobial and antibiofilm evaluation of thymol, sodium azide, and sodium lauryl sulfate against multidrug-resistant pathogens: An integrated experimental and computational study

Kamal A. Qureshi, Adil Parvez

published 07 Apr 2026

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Elucidating the binding mechanism of Caralluma tuberculata metabolites with type 2 diabetes targets through molecular docking and dynamics simulations

Amir Ali, Zia-ur-Rehman Mashwani, Ashfaq Ahmad, Juan Pedro Luna-Arias, Gabriela Medina-Pérez, Ajaz Ahmad

published 03 Apr 2026

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Hepatic transcriptomic responses in gravid and non-gravid rats exposed to HFPO-DA: Analyses to inform the role of maternal effects in neonatal toxicity

Melissa M. Heintz, Chad M. Thompson, Jeffrey C. Wolf, John M. Rogers, Laurie C. Haws

published 01 Apr 2026

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Predicted antiviral potential of phytochemicals prolific in Cleistanthus bracteosus Jabl. and essential oils of Artemisia scoparia and Thuja orientalis against Nipah virus and Human metapneumovirus: An AI-driven in-silico study

Mackingsley Kushan Dassanayake, Teng-Jin Khoo, Chien Hwa Chong, Mohammed Tahir Ansari, Patrick Di Martino, Fernando Berton Zanchi, Adam Figiel, Antoni Szumny, Omar Ashraf Elfar, Christophe Wiart, Rachael Symonds

published 31 Mar 2026

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Unraveling the toxicological impact of Bisphenol A exposure on dermatomyositis: An integration of network toxicology and machine learning approaches

Lili Cheng, Zhongfu Tang, Ming Li, Chuanbing Huang

published 30 Mar 2026

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Plasma heme pool compartmentalization is linked to pathophysiology in Sickle Cell Disease

Moritz Saxenhofer, Daniel Couto, Sandra Mena Perez, Marlies Illi, Justine Brodard, Linet Njue, Ioannis Chanias, Cesare Medri, Gerasimos Tsilimidos, Nicole Hadorn, Christelle Chirlias, Ana-Patricia Batista Mesquita, Lucas Veuthey, Anna Schnell, Stefanie Graeter, Gregory J. Kato, Jacqueline Adam, Ramona Merki, Emmanuel Levrat, Kaveh Samii, Mila Keiser, Kathrin Susann Bieri, Alan G. Haynes, Anne Angelillo-Scherrer, Lorenzo Alberio, Francesco Grandoni, Mathilde Gavillet, Thomas Gentinetta, Alicia Rovó, Alexander Schaub

published 26 Mar 2026

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Identification of polyphenols as novel neuropilin-1 cendR pocket inhibitors to block SARS-CoV-2 entry and enhance variant resistance

Farid Ataya, Abir Alamro, Amani Alghamdi, Dalia Fouad

published 23 Mar 2026

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Elucidating the potential carcinogenic molecular mechanisms of parabens in head and neck squamous cell carcinoma through network toxicology and molecular docking

Lei Zhao, Jianwang Yang, Tao Liu, Huan Cao, Miaomiao Yu, Baoshan Wang

published 23 Mar 2026

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Nonmyeloablative pentostatin-cyclophosphamide preconditioning improves rates of engraftment in adults undergoing haploidentical HCT for sickle cell disease

Emily Limerick, Matthew Hsieh, Jackie Queen, Mary Lacy Grecco, Julia Varga, Jennifer Brooks, Wynona Coles, Neal Jeffries, Courtney D. Fitzhugh

published 23 Mar 2026

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Food and feed safety of a novel Vip3C insecticidal protein derived from Paenibacillus spp. for protection of crop plants against key Lepidopteran pests

Lucas J. McKinnon, Rong Wang, Cunxi Wang, Scott Saracco, Colton Kessenich, Virginia M. Johnson, Jennifer Calcaterra, Gregory Frierdich, Eric Bretsnyder, Luting Fang, Bingyao Li, Tianbo Xu

published 18 Mar 2026

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Functional effects of extracellular vesicles altered by a per- and polyfluoroalkyl substance mixture: In vitro liver cytotoxicity and proteomic expression alterations

Celeste K. Carberry, Angie L. Mordant, Christine A. Mills, Hadley Hartwell, Victoria F. Carberry, Lauren Simendinger, Elise Hickman, Laura E. Herring, Julia E. Rager

published 18 Mar 2026

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