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Tight junctions

Quantitative proteomic analysis reveals key proteins involved in radiation-induced brain injury

Jing Liu, Junshuang Wang, Shuang Lv, Hengjiao Wang, Defu Yang, Ying Zhang, Ying Li, Huiling Qu, Ying Xu, Ying Yan

published 25 Nov 2025

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Development and characterization of a 2D porcine colonic organoid model for studying intestinal physiology and barrier function

Masina Plenge, Nadine Schnepel, Mathias Müsken, Judith Rohde, Ralph Goethe, Gerhard Breves, Gemma Mazzuoli-Weber, Pascal Benz

published 07 May 2025

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Curcumin ameliorates aging-induced blood-testis barrier disruption by regulating AMPK/mTOR mediated autophagy

Chen Xue, Zhenxing Yan, Wenjing Cheng, Dong Zhang, Rong Zhang, Hongwei Duan, Lihong Zhang, Xiaofei Ma, Junjie Hu, Jian Kang, Xiaojun Ma

published 24 Apr 2025

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Digital PCR characterizes epithelial cell populations in murine duodenal organoids

Karla Acosta-Virgen, Hugo David González-Conchillos, Gabriela Vallejo-Flores, Lizbeth Iliana Salazar-Villatoro, Ernesto Guerrero-Sánchez, Adolfo Martínez-Palomo, Martha Espinosa-Cantellano

published 13 Mar 2025

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Hyaluronic acid: Function and location in the urothelial barrier for bladder pain syndrome/interstitial cystitis, an in vitro study

Charlotte J. van Ginkel, Cléo D.M. Baars, Dorien M. Tiemessen, Cornelius F.J. Jansen, Frank M.J. Martens, Jack A. Schalken, Dick A.W. Janssen

published 26 Feb 2025

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Unveiling endothelial cell border heterogeneity: VE-cadherin adherens junction stratification by deep convolutional neural networks

Rudmer J. Postma, Susan E. Fischer, Roel Bijkerk, Anton Jan van Zonneveld

published 06 Jan 2025

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miRNA-328-3p regulates ZO-1 expression and inhibits PEDV proliferation via the PLC-β1-PKC pathway

Han Zhao, Jiayu Zhang, Dengliang Li, Zhanding Cui, Jiuyuan Liu, Di Bao, Yiming Wei, Xinyue Zhang, Zhimin Wu, Tianqi Zhang, Kai Wang, Shushuai Yi, Wei Lian, Guixue Hu

published 03 Jan 2025

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Butyric acid alleviates LPS-induced intestinal mucosal barrier damage by inhibiting the RhoA/ROCK2/MLCK signaling pathway in Caco2 cells

Luqiong Liu, Tong Chen, Zhenrong Xie, Yongjin Zhang, Chenglu He, Yongkun Huang

published 26 Dec 2024

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HSP105 inhibition downregulates store-operated calcium entry and promotes acute UVB-induced tight junction disruption

Kaiyi Zhou, Siyu Luo, Qinxiao Wang, Qian Ye, Sheng Fang

published 05 Dec 2024

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An examination of the mechanisms driving the therapeutic effects of an AAV expressing a soluble variant of VEGF receptor-1

Seo Yun Moon, Hee Jong Kim, Jin Kwon Kim, Jin Kim, Jun-Sub Choi, So-Yoon Won, Keerang Park, Steven Hyun Seung Lee

published 11 Jul 2024

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The impact of microplastics polystyrene on the microscopic structure of mouse intestine, tight junction genes and gut microbiota

Qi-Ling Su, Jiang Wu, Shao-Wen Tan, Xiao-Yun Guo, Ding-Zhe Zou, Kai Kang

published 05 Jun 2024

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The barrier-protective effect of β-eudesmol against type 2-inflammatory cytokine-induced tight junction disassembly in airway epithelial cells

Phuntila Tharabenjasin, Aekkacha Moonwiriyakit, Jenjira Sontikun, Kanokphorn Timpratueang, Suhaibee Kuno, Thitinan Aiebchun, Nathjanan Jongkon, Rungrawee Mongkolrob, Noel Pabalan, Kiattawee Choowongkomon, Chatchai Muanprasat

published 30 Apr 2024

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Hope for vascular cognitive impairment: Ac-YVAD-cmk as a novel treatment against white matter rarefaction

Yun-An Lim, Li Si Tan, Wei Thye Lee, Wei Liang Sim, Yang Lv, Maki Takakuni, Satoshi Saito, Masafumi Ihara, Thiruma Valavan Arumugam, Christopher Chen, Fred Wai-Shiu Wong, Gavin Stewart Dawe

published 17 Apr 2024

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