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Thymocytes

Zfat-Deficiency Results in a Loss of CD3ζ Phosphorylation with Dysregulation of ERK and Egr Activities Leading to Impaired Positive Selection

Masahiro Ogawa, Tadashi Okamura, Shuhei Ishikura, Keiko Doi, Hiroshi Matsuzaki, Yoko Tanaka, Takeharu Ota, Kunihiro Hayakawa, Harumi Suzuki, Toshiyuki Tsunoda, Takehiko Sasazuki, Senji Shirasawa

published 03 Oct 2013

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Single-Cell Analysis of Thymocyte Differentiation: Identification of Transcription Factor Interactions and a Major Stochastic Component in αβ-Lineage Commitment

Amine Boudil, Lamia Skhiri, Serge Candéias, Valérie Pasqualetto, Agnès Legrand, Marie Bedora-Faure, Laetitia Gautreau-Rolland, Benedita Rocha, Sophie Ezine

published 01 Oct 2013

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Keratin 8 Is Required for the Maintenance of Architectural Structure in Thymus Epithelium

Chikako Odaka, Anne Loranger, Kazuya Takizawa, Michel Ouellet, Michel J. Tremblay, Shigeo Murata, Akihito Inoko, Masaki Inagaki, Normand Marceau

published 24 Sep 2013

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Established Thymic Epithelial Progenitor/Stem Cell-Like Cell Lines Differentiate into Mature Thymic Epithelial Cells and Support T Cell Development

Pengfei Chen, Jun Zhang, Yu Zhan, Juanjuan Su, Yarui Du, Guoliang Xu, Yufang Shi, Ulrich Siebenlist, Xiaoren Zhang

published 23 Sep 2013

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Cell-Intrinsic Role for NF-kappa B-Inducing Kinase in Peripheral Maintenance but Not Thymic Development of Foxp3⁺ Regulatory T Cells in Mice

Susan E. Murray

published 20 Sep 2013

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Diacylglycerol Kinase Zeta Positively Controls the Development of iNKT-17 Cells

Jinhong Wu, Shudan Shen, Jialong Yang, Zhenwei Xia, Xiao-Ping Zhong

published 20 Sep 2013

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Vascular Endothelial Growth Factor Receptor Inhibitor SU5416 Suppresses Lymphocyte Generation and Immune Responses in Mice by Increasing Plasma Corticosterone

Jamison J. Grailer, Douglas A. Steeber

published 16 Sep 2013

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In Silico Modeling of Itk Activation Kinetics in Thymocytes Suggests Competing Positive and Negative IP₄ Mediated Feedbacks Increase Robustness

Sayak Mukherjee, Stephanie Rigaud, Sang-Cheol Seok, Guo Fu, Agnieszka Prochenka, Michael Dworkin, Nicholas R. J. Gascoigne, Veronica J. Vieland, Karsten Sauer, Jayajit Das

published 16 Sep 2013

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Contrasting Quiescent G₀ Phase with Mitotic Cell Cycling in the Mouse Immune System

Michio Tomura, Asako Sakaue-Sawano, Yoshiko Mori, Mitsuyo Takase-Utsugi, Akihiro Hata, Kenji Ohtawa, Osami Kanagawa, Atsushi Miyawaki

published 16 Sep 2013

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Differential Requirement for CCR4 in the Maintenance but Not Establishment of the Invariant Vγ5⁺ Dendritic Epidermal T-Cell Pool

Kyoko Nakamura, Andrea J. White, Sonia M. Parnell, Peter J. Lane, Eric J. Jenkinson, William E. Jenkinson, Graham Anderson

published 12 Sep 2013

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Interleukin-21 Accelerates Thymic Recovery from Glucocorticoïd-Induced Atrophy

Moutih Rafei, Maude Dumont-Lagacé, Alexandre Rouette, Claude Perreault

published 02 Sep 2013

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IL-4 and IL-4 Receptor Expression Is Dispensable for the Development and Function of Natural Killer T Cells

Archna Sharma, Rosa Berga-Bolanos, Dil Afroz Sultana, Jyoti Misra Sen

published 26 Aug 2013

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A Simple Model System Enabling Human CD34⁺ Cells to Undertake Differentiation Towards T Cells

Antonio Lapenna, Christopher B-Lynch, Chrysa Kapeni, Richard Aspinall

published 23 Jul 2013

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