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Thrombin

Co-ordinated spatial propagation of blood plasma clotting and fibrinolytic fronts

Ansar S. Zhalyalov, Mikhail A. Panteleev, Marina A. Gracheva, Fazoil I. Ataullakhanov, Alexey M. Shibeko

published 07 Jul 2017

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An in silico and in vitro approach to elucidate the impact of residues flanking the cleavage scissile bonds of FVIII

Behnaz Pezeshkpoor, Ursula Schreck, Arijit Biswas, Julia Driesen, Ann-Cristin Berkemeier, Anna Pavlova, Jens Müller, Johannes Oldenburg

published 06 Jul 2017

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Differential stability of therapeutic peptides with different proteolytic cleavage sites in blood, plasma and serum

Roland Böttger, Ralf Hoffmann, Daniel Knappe

published 02 Jun 2017

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The PET and LIM1-2 domains of testin contribute to intramolecular and homodimeric interactions

Stefano Sala, Marie Catillon, Ermin Hadzic, Elisabeth Schaffner-Reckinger, Marleen Van Troys, Christophe Ampe

published 18 May 2017

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Contribution of thrombin-reactive brain pericytes to blood-brain barrier dysfunction in an in vivo mouse model of obesity-associated diabetes and an in vitro rat model

Takashi Machida, Fuyuko Takata, Junichi Matsumoto, Tomoyuki Miyamura, Ryosuke Hirata, Ikuya Kimura, Yasufumi Kataoka, Shinya Dohgu, Atsushi Yamauchi

published 10 May 2017

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Decreased prothrombin conversion and reduced thrombin inactivation explain rebalanced thrombin generation in liver cirrhosis

Romy M. W. Kremers, Marie-Claire Kleinegris, Marisa Ninivaggi, Bas de Laat, Hugo ten Cate, Ger H. Koek, Rob J. Wagenvoord, H. Coenraad Hemker

published 04 May 2017

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Prediction of bleeding risk in patients taking vitamin K antagonists using thrombin generation testing

Saartje Bloemen, Suzanne Zwaveling, Hugo ten Cate, Arina ten Cate-Hoek, Bas de Laat

published 04 May 2017

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Tissue factor-dependent coagulation activation by heme: A thromboelastometry study

Gleice Regina de Souza, Bidossessi Wilfried Hounkpe, Maiara Marx Luz Fiusa, Marina Pereira Colella, Joyce M. Annichino-Bizzacchi, Fabiola Traina, Fernando Ferreira Costa, Erich Vinicius De Paula

published 24 Apr 2017

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Global measurement of coagulation in plasma from normal and haemophilia dogs using a novel modified thrombin generation test – Demonstrated in vitro and ex vivo

Daniel Elenius Madsen, Timothy C. Nichols, Elizabeth P. Merricks, Emily K. Waters, Bo Wiinberg

published 06 Apr 2017

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The expression and localization of RNase and RNase inhibitor in blood cells and vascular endothelial cells in homeostasis of the vascular system

Ayaka Ohashi, Aya Murata, Yuichiro Cho, Shizuko Ichinose, Yuriko Sakamaki, Miwako Nishio, Osamu Hoshi, Silvia Fischer, Klaus T. Preissner, Takatoshi Koyama

published 22 Mar 2017

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Licochalcones extracted from Glycyrrhiza inflata inhibit platelet aggregation accompanied by inhibition of COX-1 activity

Asa Okuda-Tanino, Daiki Sugawara, Takumi Tashiro, Masaya Iwashita, Yutaro Obara, Takahiro Moriya, Chisato Tsushima, Daisuke Saigusa, Yoshihisa Tomioka, Kuniaki Ishii, Norimichi Nakahata

published 10 Mar 2017

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Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor

Michel W. J. Smeets, Ruben Bierings, Henriet Meems, Frederik P. J. Mul, Dirk Geerts, Alexander P. J. Vlaar, Jan Voorberg, Peter L. Hordijk

published 01 Mar 2017

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Application of an optimized flow cytometry-based quantification of Platelet Activation (PACT): Monitoring platelet activation in platelet concentrates

Cécile H. Kicken, Mark Roest, Yvonne M. C. Henskens, Bas de Laat, Dana Huskens

published 16 Feb 2017

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