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Thrombin

A Novel Small Molecule 1,2,3,4,6-penta-O-galloyl-α-D-glucopyranose Mimics the Antiplatelet Actions of Insulin

Rehana Perveen, Kevin Funk, Jean Thuma, Shelli Wulf Ridge, Yanyan Cao, Jan Willem N. Akkerman, Xiaozhuo Chen, Huzoor Akbar

published 02 Nov 2011

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Crystal Structure of Thrombin in Complex with S-Variegin: Insights of a Novel Mechanism of Inhibition and Design of Tunable Thrombin Inhibitors

Cho Yeow Koh, Sundramurthy Kumar, Maria Kazimirova, Patricia A. Nuttall, Uvaraj P. Radhakrishnan, Seongcheol Kim, Pudur Jagadeeswaran, Takayuki Imamura, Jun Mizuguchi, Sadaaki Iwanaga, Kunchithapadam Swaminathan, R. Manjunatha Kini

published 28 Oct 2011

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Syncytiotrophoblast Microvesicles Released from Pre-Eclampsia Placentae Exhibit Increased Tissue Factor Activity

Chris Gardiner, Dionne S. Tannetta, Carol A. Simms, Paul Harrison, Christopher W. G. Redman, Ian L. Sargent

published 14 Oct 2011

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Applications of Site-Specific Labeling to Study HAMLET, a Tumoricidal Complex of α-Lactalbumin and Oleic Acid

Natalia Mercer, Boopathy Ramakrishnan, Elizabeth Boeggeman, Pradman K. Qasba

published 10 Oct 2011

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Structure and Behavior of Human α-Thrombin upon Ligand Recognition: Thermodynamic and Molecular Dynamics Studies

Vivian de Almeira Silva, Maria Thereza Cargnelutti, Guilherme M. Giesel, Leonardo C. Palmieri, Robson Q. Monteiro, Hugo Verli, Luis Mauricio T. R. Lima

published 14 Sep 2011

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Biological Activity of CXCL8 Forms Generated by Alternative Cleavage of the Signal Peptide or by Aminopeptidase-Mediated Truncation

Anneleen Mortier, Nele Berghmans, Isabelle Ronsse, Karolien Grauwen, Steve Stegen, Jo Van Damme, Paul Proost

published 31 Aug 2011

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Opposing Effects of the Angiopoietins on the Thrombin-Induced Permeability of Human Pulmonary Microvascular Endothelial Cells

Melanie van der Heijden, Geerten P. van Nieuw Amerongen, Jan van Bezu, Marinus A. Paul, A. B. Johan Groeneveld, Victor W. M. van Hinsbergh

published 15 Aug 2011

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Metabolomics-Driven Nutraceutical Evaluation of Diverse Green Tea Cultivars

Yoshinori Fujimura, Kana Kurihara, Megumi Ida, Reia Kosaka, Daisuke Miura, Hiroyuki Wariishi, Mari Maeda-Yamamoto, Atsushi Nesumi, Takeshi Saito, Tomomasa Kanda, Koji Yamada, Hirofumi Tachibana

published 10 Aug 2011

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Gene Targeting Implicates Cdc42 GTPase in GPVI and Non-GPVI Mediated Platelet Filopodia Formation, Secretion and Aggregation

Huzoor Akbar, Xun Shang, Rehana Perveen, Mark Berryman, Kevin Funk, James F. Johnson, Narendra N. Tandon, Yi Zheng

published 18 Jul 2011

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Granzyme K Activates Protease-Activated Receptor-1

Dawn M. Cooper, Dmitri V. Pechkovsky, Tillie L. Hackett, Darryl A. Knight, David J. Granville

published 30 Jun 2011

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Acyclic Identification of Aptamers for Human alpha-Thrombin Using Over-Represented Libraries and Deep Sequencing

Gillian V. Kupakuwana, James E. Crill II, Mark P. McPike, Philip N. Borer

published 19 May 2011

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New Synthetic Thrombin Inhibitors: Molecular Design and Experimental Verification

Elena I. Sinauridze, Alexey N. Romanov, Irina V. Gribkova, Olga A. Kondakova, Stepan S. Surov, Aleksander S. Gorbatenko, Andrey A. Butylin, Mikhail Yu. Monakov, Alexey A. Bogolyubov, Yuryi V. Kuznetsov, Vladimir B. Sulimov, Fazoyl I. Ataullakhanov

published 16 May 2011

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Evaluation of the Efficacy and Safety of Rivaroxaban Using a Computer Model for Blood Coagulation

Rolf Burghaus, Katrin Coboeken, Thomas Gaub, Lars Kuepfer, Anke Sensse, Hans-Ulrich Siegmund, Wolfgang Weiss, Wolfgang Mueck, Joerg Lippert

published 22 Apr 2011

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