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Thrombin

Phage Display of the Serpin Alpha-1 Proteinase Inhibitor Randomized at Consecutive Residues in the Reactive Centre Loop and Biopanned with or without Thrombin

Benjamin M. Scott, Wadim L. Matochko, Richard F. Gierczak, Varsha Bhakta, Ratmir Derda, William P. Sheffield

published 10 Jan 2014

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Profound Morphological Changes in the Erythrocytes and Fibrin Networks of Patients with Hemochromatosis or with Hyperferritinemia, and Their Normalization by Iron Chelators and Other Agents

Etheresia Pretorius, Janette Bester, Natasha Vermeulen, Boguslaw Lipinski, George S. Gericke, Douglas B. Kell

published 09 Jan 2014

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Phosphoproteomic Analysis of Platelets Activated by Pro-Thrombotic Oxidized Phospholipids and Thrombin

Alejandro Zimman, Bjoern Titz, Evangelia Komisopoulou, Sudipta Biswas, Thomas G. Graeber, Eugene A. Podrez

published 06 Jan 2014

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Glaucocalyxin A Inhibits Platelet Activation and Thrombus Formation Preferentially via GPVI Signaling Pathway

Wei Li, Xiaorong Tang, Wenxiu Yi, Qiang Li, Lijie Ren, Xiaohui Liu, Chunjun Chu, Yukio Ozaki, Jian Zhang, Li Zhu

published 30 Dec 2013

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Abl Family Kinases Regulate Endothelial Barrier Function In Vitro and in Mice

Elizabeth M. Chislock, Ann Marie Pendergast

published 19 Dec 2013

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Rho Associated Coiled-Coil Kinase-1 Regulates Collagen-Induced Phosphatidylserine Exposure in Platelets

Swapan K. Dasgupta, Anhquyen Le, Sandra B. Haudek, Mark L. Entman, Rolando E. Rumbaut, Perumal Thiagarajan

published 16 Dec 2013

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Streptococcal SpeB Cleaved PAR-1 Suppresses ERK Phosphorylation and Blunts Thrombin-Induced Platelet Aggregation

Miriam Ender, Federica Andreoni, Annelies Sophie Zinkernagel, Reto Andreas Schuepbach

published 22 Nov 2013

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Salmon and Human Thrombin Differentially Regulate Radicular Pain, Glial-Induced Inflammation and Spinal Neuronal Excitability through Protease-Activated Receptor-1

Jenell R. Smith, Peter P. Syre, Shaina A. Oake, Kristen J. Nicholson, Christine L. Weisshaar, Katrina Cruz, Robert Bucki, Bethany C. Baumann, Paul A. Janmey, Beth A. Winkelstein

published 20 Nov 2013

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Vascular Immunotargeting to Endothelial Determinant ICAM-1 Enables Optimal Partnering of Recombinant scFv-Thrombomodulin Fusion with Endogenous Cofactor

Colin F. Greineder, Ann-Marie Chacko, Sergei Zaytsev, Blaine J. Zern, Ronald Carnemolla, Elizabeth D. Hood, Jingyan Han, Bi-Sen Ding, Charles T. Esmon, Vladimir R. Muzykantov

published 14 Nov 2013

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The Effect of Factor VIII Deficiencies and Replacement and Bypass Therapies on Thrombus Formation under Venous Flow Conditions in Microfluidic and Computational Models

Abimbola A. Onasoga-Jarvis, Karin Leiderman, Aaron L. Fogelson, Michael Wang, Marilyn J. Manco-Johnson, Jorge A. Di Paola, Keith B. Neeves

published 13 Nov 2013

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Reversal of Apixaban Induced Alterations in Hemostasis by Different Coagulation Factor Concentrates: Significance of Studies In Vitro with Circulating Human Blood

Gines Escolar, Victor Fernandez-Gallego, Eduardo Arellano-Rodrigo, Jaume Roquer, Joan Carles Reverter, Victoria Veronica Sanz, Patricia Molina, Irene Lopez-Vilchez, Maribel Diaz-Ricart, Ana Maria Galan

published 11 Nov 2013

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Cyclic Nucleotide Dependent Dephosphorylation of Regulator of G-Protein Signaling 18 in Human Platelets

Kristina Gegenbauer, Zoltan Nagy, Albert Smolenski

published 07 Nov 2013

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Tracking 20 Years of Compound-to-Target Output from Literature and Patents

Christopher Southan, Peter Varkonyi, Kiran Boppana, Sarma A.R.P. Jagarlapudi, Sorel Muresan

published 29 Oct 2013

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