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Thermal stability

Probing a Polar Cluster in the Retinal Binding Pocket of Bacteriorhodopsin by a Chemical Design Approach

Rosana Simón-Vázquez, Marta Domínguez, Víctor A. Lórenz-Fonfría, Susana Álvarez, José-Luís Bourdelande, Ángel R. de Lera, Esteve Padrós, Alex Perálvarez-Marín

published 03 Aug 2012

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Intramolecular Epistasis and the Evolution of a New Enzymatic Function

Sajid Noor, Matthew C. Taylor, Robyn J. Russell, Lars S. Jermiin, Colin J. Jackson, John G. Oakeshott, Colin Scott

published 29 Jun 2012

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Rational Redesign of Glucose Oxidase for Improved Catalytic Function and Stability

J. Todd Holland, Jason C. Harper, Patricia L. Dolan, Monica M. Manginell, Dulce C. Arango, Julia A. Rawlings, Christopher A. Apblett, Susan M. Brozik

published 13 Jun 2012

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Characterization of 4-HNE Modified L-FABP Reveals Alterations in Structural and Functional Dynamics

Rebecca L. Smathers, Kristofer S. Fritz, James J. Galligan, Colin T. Shearn, Philip Reigan, Michael J. Marks, Dennis R. Petersen

published 06 Jun 2012

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Collagen-Like Proteins in Pathogenic E. coli Strains

Neelanjana Ghosh, Thomas J. McKillop, Thomas A. Jowitt, Marjorie Howard, H. Davies-Strickleton, David F. Holmes, Ian S. Roberts, Jordi Bella

published 06 Jun 2012

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On the Mechanism of Action of SJ-172550 in Inhibiting the Interaction of MDM4 and p53

Michal Bista, David Smithson, Aleksandra Pecak, Gabriella Salinas, Katarzyna Pustelny, Jaeki Min, Artur Pirog, Kristin Finch, Michal Zdzalik, Brett Waddell, Benedykt Wladyka, Sylwia Kedracka-Krok, Michael A. Dyer, Grzegorz Dubin, R. Kiplin Guy

published 04 Jun 2012

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Differential Scanning Fluorometry Signatures as Indicators of Enzyme Inhibitor Mode of Action: Case Study of Glutathione S-Transferase

Wendy A. Lea, Anton Simeonov

published 30 Apr 2012

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Small, N-Terminal Tags Activate Parkin E3 Ubiquitin Ligase Activity by Disrupting Its Autoinhibited Conformation

Lynn Burchell, Viduth K. Chaugule, Helen Walden

published 04 Apr 2012

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Thermal Variability Increases the Impact of Autumnal Warming and Drives Metabolic Depression in an Overwintering Butterfly

Caroline M. Williams, Katie E. Marshall, Heath A. MacMillan, Jason D. K. Dzurisin, Jessica J. Hellmann, Brent J. Sinclair

published 30 Mar 2012

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Functional Validation of Hydrophobic Adaptation to Physiological Temperature in the Small Heat Shock Protein αA-crystallin

Mason Posner, Andor J. Kiss, Jackie Skiba, Amy Drossman, Monika B. Dolinska, J. Fielding Hejtmancik, Yuri V. Sergeev

published 29 Mar 2012

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Rugged Single Domain Antibody Detection Elements for Bacillus anthracis Spores and Vegetative Cells

Scott A. Walper, George P. Anderson, P. Audrey Brozozog Lee, Richard H. Glaven, Jinny L. Liu, Rachel D. Bernstein, Dan Zabetakis, Linwood Johnson, Jill M. Czarnecki, Ellen R. Goldman

published 06 Mar 2012

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Molecular Insights on Pathogenic Effects of Mutations Causing Phosphoglycerate Kinase Deficiency

Laurent R. Chiarelli, Simone M. Morera, Paola Bianchi, Elisa Fermo, Alberto Zanella, Alessandro Galizzi, Giovanna Valentini

published 14 Feb 2012

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Universality of Thermodynamic Constants Governing Biological Growth Rates

Ross Corkrey, June Olley, David Ratkowsky, Tom McMeekin, Tom Ross

published 14 Feb 2012

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