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T cells

Single-cell transcriptomics reveals immunosuppressive microenvironment and highlights tumor-promoting macrophage cells in Glioblastoma

Han Cheng, Yan Yan, Biao Zhang, Zhuolin Ma, Siwen Fu, Zhi Ji, Ziyi Zou, Qin Wang

published 07 Apr 2025

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Comprehensive analysis of CMTM family and immune infiltration in esophageal carcinoma

Liying Xue, Shuting Gou, Yu Zhang, Ruirui Yuan, Chang Dong, Rongyao Hao, Na An, Xianghong Zhang, Jie Li

published 03 Apr 2025

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Association of a CHEK2 somatic variant with tumor microenvironment calprotectin expression predicts platinum resistance in a small cohort of ovarian carcinoma

Izabela Ferreira Gontijo de Amorim, Carolina Pereira de Souza Melo, Ramon de Alencar Pereira, Sidnéa Macioci Cunha, Thalía Rodrigues de Souza Zózimo, Fábio Ribeiro Queiroz, Iago de Oliveira Peixoto, Luciana Maria Silva Lopes, Laurence Rodrigues do Amaral, Matheus de Souza Gomes, Juliana Almeida Oliveira, Eduardo Batista Cândido, Paulo Guilherme de Oliveira Salles, Letícia da Conceição Braga

published 27 Mar 2025

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Identification of glucocorticoid-related genes in systemic lupus erythematosus using bioinformatics analysis and machine learning

Yinghao Ren, Weiqiang Chen, Yuhao Lin, Zeyu Wang, Weiliang Wang

published 25 Mar 2025

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Single-cell RNA-seq reveals disease-specific CD8+ T cell clonal expansion and a high frequency of transcriptionally distinct double-negative T cells in diabetic NOD mice

Md Zohorul Islam, Sam Zimmerman, Alexis Lindahl, Jon Weidanz, Jose Ordovas-Montanes, Aleksandar Kostic, Jacob Luber, Michael Robben

published 19 Mar 2025

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Understanding the aliya pulsed electric field dose-response relationship: Implications for ablation size, thermal load, and immune response in an orthotopic murine breast cancer model

Ebtesam H. O. Nafie, Chiara Pastori, Rupsa Acharya, Rosa Kaviani, David Hunter, Waleed Shalaby, William S. Krimsky, Robert E. Neal II

published 13 Feb 2025

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Human responses to the DNA prime/chimpanzee adenovirus (ChAd63) boost vaccine identify CSP, AMA1 and TRAP MHC Class I-restricted epitopes

Harini Ganeshan, Jun Huang, Maria Belmonte, Arnel Belmonte, Sandra Inoue, Rachel Velasco, Santina Maiolatesi, Keith Limbach, Noelle Patterson, Marvin J. Sklar, Lorraine Soisson, Judith E. Epstein, Kimberly A. Edgel, Bjoern Peters, Michael R. Hollingdale, Eileen Villasante, Christopher A. Duplessis, Martha Sedegah

published 13 Feb 2025

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Bronchoalveolar lavage single-cell transcriptomics reveals immune dysregulations driving COVID-19 severity

Clinton Njinju Asaba, Razieh Bitazar, Patrick Labonté, Terence Ndonyi Bukong

published 10 Feb 2025

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Effect of cytotoxic CD8+ T-cells secretory proteins on hypoxic pancreatic cancer cells

Eiman Abdo, Mohammad A. Ismail, Sabal Al Hadidi, Mairvat Al-Mrahleh, Tareq Saleh, Malik Zihlif, Nidaa A. Ababneh

published 30 Jan 2025

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Low agreement and frequent invalid controls in two SARS-CoV-2 T-cell assays in people with compromised immune function

Annette Audigé, Alain Amstutz, Macé M. Schuurmans, Patrizia Amico, Dominique L. Braun, Marcel P. Stoeckle, Barbara Hasse, René Hage, Dominik Damm, Michael Tamm, Nicolas J. Mueller, Huldrych F. Günthard, Michael T. Koller, Christof M. Schönenberger, Alexandra Griessbach, Niklaus D. Labhardt, Roger D. Kouyos, Alexandra Trkola, Michael Huber, Katharina Kusejko, Heiner C. Bucher, Irene A. Abela, Matthias Briel, Frédérique Chammartin, Benjamin Speich, the Swiss HIV Cohort Study, and the Swiss Transplant Cohort Study

published 24 Jan 2025

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Investigating the functional and structural effect of non-synonymous single nucleotide polymorphisms in the cytotoxic T-lymphocyte antigen-4 gene: An in-silico study

Md. Mostafa Kamal, Kazi Fahmida Haque Shantanu, Shamiha Tabassum Teeya, Md. Motiar Rahman, A. K. M. Munzurul Hasan, Douglas P. Chivers, Tanveer A. Wani, Atekah Hazzaa Alshammari, Mahesh Rachamalla, Francisco Carlos da Silva Junior, Md. Munnaf Hossen

published 24 Jan 2025

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Low regulatory T-cells frequency is associated with graft rejection after small bowel transplantation: Clinical and experimental evidence

Rodrigo Papa-Gobbi, Pablo Stringa, Maria Virginia Gentilini, Ivana Ivanoff, Mariana Machuca, Nidia Monserrat Arreola, Javier Serradilla, Karla Estefanía-Fernández, Paloma Talayero, María Velayos, Elena Sánchez—Zapardiel, Gabriel Gondolesi, Ane Andrés-Moreno, Martin Rumbo, Francisco Hernández-Oliveros

published 24 Jan 2025

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Cellular senescence-associated genes in rheumatoid arthritis: Identification and functional analysis

You Ao, Qing Lan, Tianhua Yu, Zhichao Wang, Jing Zhang

published 16 Jan 2025

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