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Substitution mutation

Single nucleotide polymorphism leads to daptomycin resistance causing amino acid substitution—T345I in MprF of clinically isolated MRSA strains

Masaki Nakamura, Hayato Kawada, Hiroki Uchida, Yusuke Takagi, Shuichi Obata, Ryotaro Eda, Hideaki Hanaki, Hidero Kitasato

published 22 Jan 2021

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Tyrosyl-DNA phosphodiesterases are involved in mutagenic events at a ribonucleotide embedded into DNA in human cells

Ayuna Takeishi, Hiroyuki Kogashi, Mizuki Odagiri, Hiroyuki Sasanuma, Shunichi Takeda, Manabu Yasui, Masamitsu Honma, Tetsuya Suzuki, Hiroyuki Kamiya, Kaoru Sugasawa, Kiyoe Ura, Akira Sassa

published 31 Dec 2020

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Intellectual disability-associated gain-of-function mutations in CERT1 that encodes the ceramide transport protein CERT

Hiroaki Murakami, Norito Tamura, Yumi Enomoto, Kentaro Shimasaki, Kenji Kurosawa, Kentaro Hanada

published 21 Dec 2020

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SELVa: Simulator of evolution with landscape variation

Elena Nabieva, Georgii A. Bazykin

published 02 Dec 2020

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Genetic interactions among ADAMTS metalloproteases and basement membrane molecules in cell migration in Caenorhabditis elegans

Ayaka Imanishi, Yuma Aoki, Masaki Kakehi, Shunsuke Mori, Tomomi Takano, Yukihiko Kubota, Hon-Song Kim, Yukimasa Shibata, Kiyoji Nishiwaki

published 02 Dec 2020

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Chlamydomonas reinhardtii tubulin-gene disruptants for efficient isolation of strains bearing tubulin mutations

Takako Kato-Minoura, Yutaro Ogiwara, Takashi Yamano, Hideya Fukuzawa, Ritsu Kamiya

published 23 Nov 2020

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Development of an immuno-wall device for the rapid and sensitive detection of EGFR mutations in tumor tissues resected from lung cancer patients

Naoyuki Yogo, Tetsunari Hase, Toshihiro Kasama, Keine Nishiyama, Naoya Ozawa, Takahiro Hatta, Hirofumi Shibata, Mitsuo Sato, Kazuki Komeda, Nozomi Kawabe, Kohei Matsuoka, Toyofumi Fengshi Chen-Yoshikawa, Noritada Kaji, Manabu Tokeshi, Yoshinobu Baba, Yoshinori Hasegawa

published 16 Nov 2020

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Hsp104-dependent ability to assimilate mannitol and sorbitol conferred by a truncated Cyc8 with a C-terminal polyglutamine in Saccharomyces cerevisiae

Hideki Tanaka, Kousaku Murata, Wataru Hashimoto, Shigeyuki Kawai

published 11 Nov 2020

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Emergence of a novel chikungunya virus strain bearing the E1:V80A substitution, out of the Mombasa, Kenya 2017-2018 outbreak

Fredrick Eyase, Solomon Langat, Irina Maljkovic Berry, Francis Mulwa, Albert Nyunja, James Mutisya, Samuel Owaka, Samson Limbaso, Victor Ofula, Hellen Koka, Edith Koskei, Joel Lutomiah, Richard G. Jarman, Rosemary Sang

published 06 Nov 2020

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Deviation from Mendelian transmission of autosomal SNPs can be used to estimate germline mutations in humans exposed to ionizing radiation

Hugo Pereira Leite Filho, Irene Plaza Pinto, Lorraynne Guimarães Oliveira, Emília Oliveira Alves Costa, Alex Silva da Cruz, Daniela de Melo e Silva, Claudio Carlos da Silva, Alexandre Rodrigues Caetano, Aparecido Divino da Cruz

published 27 Oct 2020

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Emergence of highly pathogenic H5N2 and H7N1 influenza A viruses from low pathogenic precursors by serial passage in ovo

Agnes Tinuke Laleye, Celia Abolnik

published 08 Oct 2020

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Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic

Leszek J. Klimczak, Thomas A. Randall, Natalie Saini, Jian-Liang Li, Dmitry A. Gordenin

published 02 Oct 2020

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Ser-653-Asn substitution in the acetohydroxyacid synthase gene confers resistance in weedy rice to imidazolinone herbicides in Malaysia

Rabiatuladawiyah Ruzmi, Muhammad Saiful Ahmad-Hamdani, Norida Mazlan

published 14 Sep 2020

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