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Substitution mutation

MSH2/MSH6 Complex Promotes Error-Free Repair of AID-Induced dU:G Mispairs as well as Error-Prone Hypermutation of A:T Sites

Sergio Roa, Ziqiang Li, Jonathan U. Peled, Chunfang Zhao, Winfried Edelmann, Matthew D. Scharff

published 17 Jun 2010

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JAK2 V617F Constitutive Activation Requires JH2 Residue F595: A Pseudokinase Domain Target for Specific Inhibitors

Alexandra Dusa, Céline Mouton, Christian Pecquet, Murielle Herman, Stefan N. Constantinescu

published 16 Jun 2010

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A Helix Replacement Mechanism Directs Metavinculin Functions

Erumbi S. Rangarajan, Jun Hyuck Lee, S. D. Yogesha, Tina Izard

published 19 May 2010

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Transcription-Associated Mutagenesis Increases Protein Sequence Diversity More Effectively than Does Random Mutagenesis in Escherichia coli

Hyunchul Kim, Baek-Seok Lee, Masaru Tomita, Akio Kanai

published 10 May 2010

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Angiotensin I-Converting Enzyme Gln1069Arg Mutation Impairs Trafficking to the Cell Surface Resulting in Selective Denaturation of the C-Domain

Sergei M. Danilov, Sergey Kalinin, Zhenlong Chen, Elena I. Vinokour, Andrew B. Nesterovitch, David E. Schwartz, Olivier Gribouval, Marie-Claire Gubler, Richard D. Minshall

published 03 May 2010

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4E10-Resistant HIV-1 Isolated from Four Subjects with Rare Membrane-Proximal External Region Polymorphisms

Kyle J. Nakamura, Johannes S. Gach, Laura Jones, Katherine Semrau, Jan Walter, Frederic Bibollet-Ruche, Julie M. Decker, Laura Heath, William D. Decker, Moses Sinkala, Chipepo Kankasa, Donald Thea, James Mullins, Louise Kuhn, Michael B. Zwick, Grace M. Aldrovandi

published 23 Mar 2010

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Principles and Determinants of G-Protein Coupling by the Rhodopsin-Like Thyrotropin Receptor

Gunnar Kleinau, Holger Jaeschke, Catherine L. Worth, Sandra Mueller, Jorge Gonzalez, Ralf Paschke, Gerd Krause

published 18 Mar 2010

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Allosteric Regulation of HIV-1 Reverse Transcriptase by ATP for Nucleotide Selection

Masaru Yokoyama, Hiromi Mori, Hironori Sato

published 25 Jan 2010

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Promoter Recognition by a Complex of Spx and the C-Terminal Domain of the RNA Polymerase α Subunit

Michiko M. Nakano, Ann Lin, Cole S. Zuber, Kate J. Newberry, Richard G. Brennan, Peter Zuber

published 13 Jan 2010

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Explaining the Imperfection of the Molecular Clock of Hominid Mitochondria

Eva-Liis Loogväli, Toomas Kivisild, Tõnu Margus, Richard Villems

published 29 Dec 2009

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Cultivated Grapevines Represent a Symptomless Reservoir for the Transmission of Hop Stunt Viroid to Hop Crops: 15 Years of Evolutionary Analysis

Yoko Kawaguchi-Ito, Shi-Fang Li, Masaya Tagawa, Hiroyuki Araki, Masafumi Goshono, Shingen Yamamoto, Mayumi Tanaka, Masako Narita, Kazuaki Tanaka, Sheng-Xue Liu, Eishiro Shikata, Teruo Sano

published 24 Dec 2009

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Bi-Directional SIFT Predicts a Subset of Activating Mutations

William Lee, Yan Zhang, Kiran Mukhyala, Robert A. Lazarus, Zemin Zhang

published 14 Dec 2009

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Angiotensin I-Converting Enzyme Mutation (Trp1197Stop) Causes a Dramatic Increase in Blood ACE

Andrew B. Nesterovitch, Kyle D. Hogarth, Vyacheslav A. Adarichev, Elena I. Vinokour, David E. Schwartz, Julian Solway, Sergei M. Danilov

published 14 Dec 2009

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