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Substitution mutation

Molecular Dynamics of Mesophilic-Like Mutants of a Cold-Adapted Enzyme: Insights into Distal Effects Induced by the Mutations

Elena Papaleo, Marco Pasi, Matteo Tiberti, Luca De Gioia

published 07 Sep 2011

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Rational Design of Temperature-Sensitive Alleles Using Computational Structure Prediction

Christopher S. Poultney, Glenn L. Butterfoss, Michelle R. Gutwein, Kevin Drew, David Gresham, Kristin C. Gunsalus, Dennis E. Shasha, Richard Bonneau

published 02 Sep 2011

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Effect of Hydrophobic Mutations in the H2-H3 Subdomain of Prion Protein on Stability and Conversion In Vitro and In Vivo

Iva Hafner-Bratkovič, Lars Gaedtke, Andrej Ondracka, Peter Veranič, Ina Vorberg, Roman Jerala

published 01 Sep 2011

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Lys98 Substitution in Human AP Endonuclease 1 Affects the Kinetic Mechanism of Enzyme Action in Base Excision and Nucleotide Incision Repair Pathways

Nadezhda A. Timofeyeva, Vladimir V. Koval, Alexander A. Ishchenko, Murat K. Saparbaev, Olga S. Fedorova

published 01 Sep 2011

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Molecular Genetic Analysis of 103 Sporadic Colorectal Tumours in Czech Patients

Peter Vasovcak, Kristyna Pavlikova, Zdenek Sedlacek, Petr Skapa, Martin Kouda, Jiri Hoch, Anna Krepelova

published 25 Aug 2011

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Molecular Sites for the Positive Allosteric Modulation of Glycine Receptors by Endocannabinoids

Gonzalo E. Yévenes, Hanns Ulrich Zeilhofer

published 25 Aug 2011

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Divalent Metal Ion Differentially Regulates the Sequential Nicking Reactions of the GIY-YIG Homing Endonuclease I-BmoI

Benjamin P. Kleinstiver, Wesley Bérubé-Janzen, Andrew D. Fernandes, David R. Edgell

published 22 Aug 2011

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Probing the Role of Protein Surface Charge in the Activation of PrfA, the Central Regulator of Listeria monocytogenes Pathogenesis

Bobbi Xayarath, Karl W. Volz, Jennifer I. Smart, Nancy E. Freitag

published 12 Aug 2011

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Subunit Interface Residues F129 and H294 of Human RAD51 Are Essential for Recombinase Function

Ravindra Amunugama, Richard Fishel

published 12 Aug 2011

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Predicting Transcriptional Activity of Multiple Site p53 Mutants Based on Hybrid Properties

Tao Huang, Shen Niu, Zhongping Xu, Yun Huang, Xiangyin Kong, Yu-Dong Cai, Kuo-Chen Chou

published 08 Aug 2011

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Cyclin A2 Mutagenesis Analysis: A New Insight into CDK Activation and Cellular Localization Requirements

Nawal Bendris, Bénédicte Lemmers, Jean-Marie Blanchard, Nikola Arsic

published 28 Jul 2011

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Optimal Codon Identities in Bacteria: Implications from the Conflicting Results of Two Different Methods

Bin Wang, Zhu-Qing Shao, Ying Xu, Jing Liu, Yuan Liu, Yue-Yu Hang, Jian-Qun Chen

published 28 Jul 2011

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Impact of the HIV-1 env Genetic Context outside HR1–HR2 on Resistance to the Fusion Inhibitor Enfuvirtide and Viral Infectivity in Clinical Isolates

Franky Baatz, Monique Nijhuis, Morgane Lemaire, Martiene Riedijk, Annemarie M. J. Wensing, Jean-Yves Servais, Petra M. van Ham, Andy I. M. Hoepelman, Peter P. Koopmans, Herman G. Sprenger, Carole Devaux, Jean-Claude Schmit, Danielle Perez Bercoff

published 08 Jul 2011

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