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Substitution mutation

A Single Residue Substitution in the Receptor-Binding Domain of H5N1 Hemagglutinin Is Critical for Packaging into Pseudotyped Lentiviral Particles

Dong-Jiang Tang, Yuen-Man Lam, Yu-Lam Siu, Chi-Hong Lam, Shui-Ling Chu, J. S. Malik Peiris, Philippe Buchy, Béatrice Nal, Roberto Bruzzone

published 02 Nov 2012

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Assessing Predictors of Changes in Protein Stability upon Mutation Using Self-Consistency

Grant Thiltgen, Richard A. Goldstein

published 29 Oct 2012

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Site Directed Mutagenesis of Schizosaccharomyces pombe Glutathione Synthetase Produces an Enzyme with Homoglutathione Synthetase Activity

Tamara Dworeck, Martin Zimmermann

published 16 Oct 2012

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Effects of the Missense Mutations in Canine BRCA2 on BRC Repeat 3 Functions and Comparative Analyses between Canine and Human BRC Repeat 3

Yasunaga Yoshikawa, Kazuhiko Ochiai, Masami Morimatsu, Yu Suzuki, Seiichi Wada, Takahiro Taoda, Satomi Iwai, Seishiro Chikazawa, Koichi Orino, Kiyotaka Watanabe

published 12 Oct 2012

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Predicting the Functional Effect of Amino Acid Substitutions and Indels

Yongwook Choi, Gregory E. Sims, Sean Murphy, Jason R. Miller, Agnes P. Chan

published 08 Oct 2012

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Free Cholesterol Induces Higher β-Sheet Content in Aβ Peptide Oligomers by Aromatic Interaction with Phe19

Xiaolin Zhou, Jie Xu

published 25 Sep 2012

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Polymorphisms in the Human Tropoelastin Gene Modify In Vitro Self-Assembly and Mechanical Properties of Elastin-Like Polypeptides

David He, Ming Miao, Eva E. Sitarz, Lisa D. Muiznieks, Sean Reichheld, Richard J. Stahl, Fred W. Keeley, John Parkinson

published 25 Sep 2012

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Amino Acids Transitioning of 2009 H1N1pdm in Taiwan from 2009 to 2011

Guang-Wu Chen, Kuo-Chien Tsao, Chung-Guei Huang, Yu-Nong Gong, Shih-Cheng Chang, Yi-Chun Liu, Hsiao-Han Wu, Shu-Li Yang, Tzou-Yien Lin, Yhu-Chering Huang, Shin-Ru Shih

published 24 Sep 2012

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Random Mutagenesis MAPPIT Analysis Identifies Binding Sites for Vif and Gag in Both Cytidine Deaminase Domains of Apobec3G

Isabel Uyttendaele, Delphine Lavens, Dominiek Catteeuw, Irma Lemmens, Celia Bovijn, Jan Tavernier, Frank Peelman

published 10 Sep 2012

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Two Rare Human Mitofusin 2 Mutations Alter Mitochondrial Dynamics and Induce Retinal and Cardiac Pathology in Drosophila

William H. Eschenbacher, Moshi Song, Yun Chen, Poonam Bhandari, Peter Zhao, Casey C. Jowdy, John T. Engelhard, Gerald W. Dorn II

published 05 Sep 2012

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Coevolution in RNA Molecules Driven by Selective Constraints: Evidence from 5S rRNA

Nan Cheng, Yuanhui Mao, Youyi Shi, Shiheng Tao

published 04 Sep 2012

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Complex Structure of Engineered Modular Domains Defining Molecular Interaction between ICAM-1 and Integrin LFA-1

Sungkwon Kang, Chae Un Kim, Xiaoling Gu, Roisin M. Owens, Sarah J. van Rijn, Vanissra Boonyaleepun, Yuxin Mao, Timothy A. Springer, Moonsoo M. Jin

published 30 Aug 2012

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Modeling Pathogenic Mutations of Human Twinkle in Drosophila Suggests an Apoptosis Role in Response to Mitochondrial Defects

Alvaro Sanchez-Martinez, Manuel Calleja, Susana Peralta, Yuichi Matsushima, Rosana Hernandez-Sierra, Alexander J. Whitworth, Laurie S. Kaguni, Rafael Garesse

published 28 Aug 2012

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