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Substitution mutation

Genome-Wide Analysis of Selective Constraints on High Stability Regions of mRNA Reveals Multiple Compensatory Mutations in Escherichia coli

Yuanhui Mao, Qian Li, Yinwen Zhang, Junjie Zhang, Gehong Wei, Shiheng Tao

published 27 Sep 2013

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Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox

Julien Hiblot, Guillaume Gotthard, Mikael Elias, Eric Chabriere

published 23 Sep 2013

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Mechanistic Insight into the Relationship between N-Terminal Acetylation of α-Synuclein and Fibril Formation Rates by NMR and Fluorescence

Lijuan Kang, Maria K. Janowska, Gina M. Moriarty, Jean Baum

published 18 Sep 2013

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Genetics of Type III Bartter Syndrome in Spain, Proposed Diagnostic Algorithm

Alejandro García Castaño, Gustavo Pérez de Nanclares, Leire Madariaga, Mireia Aguirre, Alvaro Madrid, Inmaculada Nadal, Mercedes Navarro, Elena Lucas, Julia Fijo, Mar Espino, Zilac Espitaletta, Luis Castaño, Gema Ariceta, RenalTube Group

published 18 Sep 2013

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Mutations in GTP Binding Protein Obg of Mycoplasma synoviae Vaccine Strain MS-H: Implications in Temperature-Sensitivity Phenotype

Muhammad A. Shahid, Philip F. Markham, John F. Markham, Marc S. Marenda, Amir H. Noormohammadi

published 17 Sep 2013

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Distal Effect of Amino Acid Substitutions in CYP2C9 Polymorphic Variants Causes Differences in Interatomic Interactions against (S)-Warfarin

Panida Lertkiatmongkol, Anunchai Assawamakin, George White, Gaurav Chopra, Pornpimol Rongnoparut, Ram Samudrala, Sissades Tongsima

published 02 Sep 2013

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Potential Elucidation of a Novel CTL Epitope in HIV-1 Protease by the Protease Inhibitor Resistance Mutation L90M

Werner Smidt

published 28 Aug 2013

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High-Levels of Acquired Drug Resistance in Adult Patients Failing First-Line Antiretroviral Therapy in a Rural HIV Treatment Programme in KwaZulu-Natal, South Africa

Justen Manasa, Richard J. Lessells, Andrew Skingsley, Kevindra K. Naidu, Marie-Louise Newell, Nuala McGrath, Tulio de Oliveira, the Southern African Treatment and Resistance Network (SATuRN)

published 21 Aug 2013

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Clinical Relevance of Gain-Of-Function Mutations of p53 in High-Grade Serous Ovarian Carcinoma

Hyo Jeong Kang, Sung-Min Chun, Kyu-Rae Kim, Insuk Sohn, Chang Ohk Sung

published 13 Aug 2013

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Slower Uncoating Is Associated with Impaired Replicative Capability of Simian-Tropic HIV-1

Ken Kono, Eri Takeda, Hiromi Tsutsui, Ayumu Kuroishi, Amy E. Hulme, Thomas J. Hope, Emi E. Nakayama, Tatsuo Shioda

published 13 Aug 2013

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An In Silico Analysis of Troponin I Mutations in Hypertrophic Cardiomyopathy of Indian Origin

Gayatri Ramachandran, Manoj Kumar, Deepa Selvi Rani, Venkateshwari Annanthapur, Narasimhan Calambur, Pratibha Nallari, Punit Kaur

published 13 Aug 2013

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Clonal Dissemination, Emergence of Mutator Lineages and Antibiotic Resistance Evolution in Pseudomonas aeruginosa Cystic Fibrosis Chronic Lung Infection

Carla López-Causapé, Estrella Rojo-Molinero, Xavier Mulet, Gabriel Cabot, Bartolomé Moyà, Joan Figuerola, Bernat Togores, José L. Pérez, Antonio Oliver

published 12 Aug 2013

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Evolution of Primary HIV Drug Resistance in a Subtype C Dominated Epidemic in Mozambique

Dulce Celina Adolfo Bila, Peter Young, Harriet Merks, Adolfo Salvador Vubil, Mussagy Mahomed, Angelo Augusto, Celina Monteiro Abreu, Nédio Jonas Mabunda, James I. Brooks, Amilcar Tanuri, Ilesh Vinodrai Jani

published 30 Jul 2013

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