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Substitution mutation

Dissection of the TssB-TssC Interface during Type VI Secretion Sheath Complex Formation

Xiang Y. Zhang, Yannick R. Brunet, Laureen Logger, Badreddine Douzi, Christian Cambillau, Laure Journet, Eric Cascales

published 25 Nov 2013

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Quantitative Identification of Mutant Alleles Derived from Lung Cancer in Plasma Cell-Free DNA via Anomaly Detection Using Deep Sequencing Data

Yoji Kukita, Junji Uchida, Shigeyuki Oba, Kazumi Nishino, Toru Kumagai, Kazuya Taniguchi, Takako Okuyama, Fumio Imamura, Kikuya Kato

published 21 Nov 2013

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Role of Cross-Cleft Contacts in NMDA Receptor Gating

Meaghan A. Paganelli, Cassandra L. Kussius, Gabriela K. Popescu

published 21 Nov 2013

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Molecular Dynamics Analysis of a Novel β3 Pro189Ser Mutation in a Patient with Glanzmann Thrombasthenia Differentially Affecting αIIbβ3 and αvβ3 Expression

Michel Laguerre, Essa Sabi, Martina Daly, Jacqueline Stockley, Paquita Nurden, Xavier Pillois, Alan T. Nurden

published 13 Nov 2013

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High Endemicity and Low Molecular Diversity of Hepatitis B Virus Infections in Pregnant Women in a Rural District of North Cameroon

Alexandra Ducancelle, Pierre Abgueguen, Jacques Birguel, Wael Mansour, Adeline Pivert, Hélène Le Guillou-Guillemette, Jean-Jacques Sobnangou, Amélie Rameau, Jean-Marie Huraux, Françoise Lunel-Fabiani

published 12 Nov 2013

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Identification and Characterization of CDH1 Germline Variants in Sporadic Gastric Cancer Patients and in Individuals at Risk of Gastric Cancer

Marica Garziera, Vincenzo Canzonieri, Renato Cannizzaro, Silvano Geremia, Laura Caggiari, Mariangela De Zorzi, Stefania Maiero, Enrico Orzes, Tiziana Perin, Stefania Zanussi, Paolo De Paoli, Valli De Re

published 29 Oct 2013

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Effect of Short- and Long-Range Interactions on Trp Rotamer Populations Determined by Site-Directed Tryptophan Fluorescence of Tear Lipocalin

Oktay K. Gasymov, Adil R. Abduragimov, Ben J. Glasgow

published 28 Oct 2013

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Molecular Characterization of Ambiguous Mutations in HIV-1 Polymerase Gene: Implications for Monitoring HIV Infection Status and Drug Resistance

Du-Ping Zheng, Margarida Rodrigues, Ebi Bile, Duc B. Nguyen, Karidia Diallo, Joshua R. DeVos, John N. Nkengasong, Chunfu Yang

published 17 Oct 2013

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Role of Key Salt Bridges in Thermostability of G. thermodenitrificans EstGtA2: Distinctive Patterns within the New Bacterial Lipolytic Enzyme Family XV

David M. Charbonneau, Marc Beauregard

published 08 Oct 2013

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Dopa-Responsive Dystonia: Functional Analysis of Single Nucleotide Substitutions within the 5’ Untranslated GCH1 Region

Ioanna A. Armata, Leonora Balaj, John K. Kuster, Xuan Zhang, Shelun Tsai, Andreas A. Armatas, Trisha J. Multhaupt-Buell, Roy Soberman, Xandra O. Breakefield, Hiroshi Ichinose, Nutan Sharma

published 04 Oct 2013

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A Polymorphism at Position 400 in the Connection Subdomain of HIV-1 Reverse Transcriptase Affects Sensitivity to NNRTIs and RNaseH Activity

David W. Wright, Ilona P. Deuzing, Philippe Flandre, Peter van den Eede, Micheline Govaert, Laurentia Setiawan, Peter V. Coveney, Anne-Geneviève Marcelin, Vincent Calvez, Charles A. B. Boucher, Nancy Beerens

published 02 Oct 2013

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A Novel MAPT Mutation, G55R, in a Frontotemporal Dementia Patient Leads to Altered Tau Function

Abhinaya Iyer, Nichole E. LaPointe, Krzysztof Zielke, Mariusz Berdynski, Elmer Guzman, Anna Barczak, Małgorzata Chodakowska-Żebrowska, Maria Barcikowska, Stuart Feinstein, Cezary Żekanowski

published 27 Sep 2013

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Quantifying the Fitness Advantage of Polymerase Substitutions in Influenza A/H7N9 Viruses during Adaptation to Humans

Judith M. Fonville, David F. Burke, Nicola S. Lewis, Leah C. Katzelnick, Colin A. Russell

published 27 Sep 2013

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