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Substitution mutation

A Simple Extension to the CMASA Method for the Prediction of Catalytic Residues in the Presence of Single Point Mutations

David I. Flores, Rogerio R. Sotelo-Mundo, Carlos A. Brizuela

published 30 Sep 2014

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Mutations in the Testis-Specific Enhancer of SOX9 in the SRY Independent Sex-Determining Mechanism in the Genus Tokudaia

Ryutaro Kimura, Chie Murata, Yoko Kuroki, Asato Kuroiwa

published 29 Sep 2014

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Acyl-Homoserine Lactone Recognition and Response Hindering the Quorum-Sensing Regulator EsaR

Daniel J. Schu, Jessica M. Scruggs, Jared S. Geissinger, Katherine G. Michel, Ann M. Stevens

published 19 Sep 2014

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Novel Mutations in FKBP10 and PLOD2 Cause Rare Bruck Syndrome in Chinese Patients

Peiran Zhou, Yi Liu, Fang Lv, Min Nie, Yan Jiang, Ou Wang, Weibo Xia, Xiaoping Xing, Mei Li

published 19 Sep 2014

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Differential Binding of Tenofovir and Adefovir to Reverse Transcriptase of Hepatitis B Virus

Formijn J. van Hemert, Ben Berkhout, Hans L. Zaaijer

published 02 Sep 2014

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Azvudine, A Novel Nucleoside Reverse Transcriptase Inhibitor Showed Good Drug Combination Features and Better Inhibition on Drug-Resistant Strains than Lamivudine In Vitro

Rui-Rui Wang, Qing-Hua Yang, Rong-Hua Luo, You-Mei Peng, Shao-Xing Dai, Xing-Jie Zhang, Huan Chen, Xue-Qing Cui, Ya-Juan Liu, Jing-Fei Huang, Jun-Biao Chang, Yong-Tang Zheng

published 21 Aug 2014

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Detection of MPLW515L/K Mutations and Determination of Allele Frequencies with a Single-Tube PCR Assay

Hiraku Takei, Soji Morishita, Marito Araki, Yoko Edahiro, Yoshitaka Sunami, Yumi Hironaka, Naohiro Noda, Yuji Sekiguchi, Satoshi Tsuneda, Akimichi Ohsaka, Norio Komatsu

published 21 Aug 2014

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Gene-Specific Function Prediction for Non-Synonymous Mutations in Monogenic Diabetes Genes

Quan Li, Xiaoming Liu, Richard A. Gibbs, Eric Boerwinkle, Constantin Polychronakos, Hui-Qi Qu

published 19 Aug 2014

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Targeted Next-Generation Sequencing Reveals Novel USH2A Mutations Associated with Diverse Disease Phenotypes: Implications for Clinical and Molecular Diagnosis

Xue Chen, Xunlun Sheng, Xiaoxing Liu, Huiping Li, Yani Liu, Weining Rong, Shaoping Ha, Wenzhou Liu, Xiaoli Kang, Kanxing Zhao, Chen Zhao

published 18 Aug 2014

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In Silico Analysis of Missense Mutations in LPAR6 Reveals Abnormal Phospholipid Signaling Pathway Leading to Hypotrichosis

Syed Irfan Raza, Dost Muhammad, Abid Jan, Raja Hussain Ali, Mubashir Hassan, Wasim Ahmad, Sajid Rashid

published 13 Aug 2014

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Overexpression of Gremlin-1 in Patients with Loeys-Dietz Syndrome: Implications on Pathophysiology and Early Disease Detection

Jasmin Wellbrock, Sara Sheikhzadeh, Leticia Oliveira-Ferrer, Hauke Stamm, Mathias Hillebrand, Britta Keyser, Marianne Klokow, Gabi Vohwinkel, Veronika Bonk, Benjamin Otto, Thomas Streichert, Stefan Balabanov, Christian Hagel, Meike Rybczynski, Frank Bentzien, Carsten Bokemeyer, Yskert von Kodolitsch, Walter Fiedler

published 12 Aug 2014

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Defining the Recognition Elements of Lewis Y-Reactive Antibodies

Somdutta Saha, Anastas Pashov, Eric R. Siegel, Ramachandran Murali, Thomas Kieber-Emmons

published 12 Aug 2014

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Improving the Anti-Toxin Abilities of the CMG2-Fc Fusion Protein with the Aid of Computational Design

Yongyi Xi, Xiaojie Wu, Lihua Gao, Yong Shao, Hui Peng, Hongxing Chen, Huipeng Chen, Xianwen Hu, Junjie Yue

published 07 Aug 2014

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