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Substitution mutation

A Cyclic Peptidic Serine Protease Inhibitor: Increasing Affinity by Increasing Peptide Flexibility

Baoyu Zhao, Peng Xu, Longguang Jiang, Berit Paaske, Tobias Kromann-Hansen, Jan K. Jensen, Hans Peter Sørensen, Zhuo Liu, Jakob T. Nielsen, Anni Christensen, Masood Hosseini, Kasper K. Sørensen, Niels Christian Nielsen, Knud J. Jensen, Mingdong Huang, Peter A. Andreasen

published 29 Dec 2014

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Frequency of COL4A3/COL4A4 Mutations amongst Families Segregating Glomerular Microscopic Hematuria and Evidence for Activation of the Unfolded Protein Response. Focal and Segmental Glomerulosclerosis Is a Frequent Development during Ageing

Louiza Papazachariou, Panayiota Demosthenous, Myrtani Pieri, Gregory Papagregoriou, Isavella Savva, Christoforos Stavrou, Michael Zavros, Yiannis Athanasiou, Kyriakos Ioannou, Charalambos Patsias, Alexia Panagides, Costas Potamitis, Kyproula Demetriou, Marios Prikis, Michael Hadjigavriel, Maria Kkolou, Panayiota Loukaidou, Androulla Pastelli, Aristos Michael, Akis Lazarou, Maria Arsali, Loukas Damianou, Ioanna Goutziamani, Andreas Soloukides, Lakis Yioukas, Avraam Elia, Ioanna Zouvani, Polycarpos Polycarpou, Alkis Pierides, Konstantinos Voskarides, Constantinos Deltas

published 16 Dec 2014

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Group 1 Allergen Genes in Two Species of House Dust Mites, Dermatophagoides farinae and D. pteronyssinus (Acari: Pyroglyphidae): Direct Sequencing, Characterization and Polymorphism

Rubaba Hamid Shafique, Pavel B. Klimov, Muhammad Inam, Farhana Riaz Chaudhary, Barry M. OConnor

published 10 Dec 2014

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Novel KRAS Gene Mutations in Sporadic Colorectal Cancer

Walid M. Naser, Mohamed A. Shawarby, Dalal M. Al-Tamimi, Arun Seth, Abdulaziz Al-Quorain, Areej M. Al Nemer, Omar M. E. Albagha

published 20 Nov 2014

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Frequency and Fitness Consequences of Bacteriophage Φ6 Host Range Mutations

Brian E. Ford, Bruce Sun, James Carpino, Elizabeth S. Chapler, Jane Ching, Yoon Choi, Kevin Jhun, Jung D. Kim, Gregory G. Lallos, Rachelle Morgenstern, Shalini Singh, Sai Theja, John J. Dennehy

published 19 Nov 2014

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Protein Thermal Stability Enhancement by Designing Salt Bridges: A Combined Computational and Experimental Study

Chi-Wen Lee, Hsiu-Jung Wang, Jenn-Kang Hwang, Ching-Ping Tseng

published 13 Nov 2014

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Phenotype-Genotype Correlation in Wilson Disease in a Large Lebanese Family: Association of c.2299insC with Hepatic and of p. Ala1003Thr with Neurologic Phenotype

Julnar Usta, Antonios Wehbeh, Khaled Rida, Omar El-Rifai, Theresa Alicia Estiphan, Tamar Majarian, Kassem Barada

published 12 Nov 2014

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Regulation of the ahpC Gene Encoding Alkyl Hydroperoxide Reductase in Mycobacterium smegmatis

Ha-Na Lee, Na-On Lee, Seung J. Han, In-Jeong Ko, Jeong-Il Oh

published 03 Nov 2014

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Generation of a Single Chain Antibody Variable Fragment (scFv) to Sense Selectively RhoB Activation

Patrick Chinestra, Aurélien Olichon, Claire Medale-Giamarchi, Isabelle Lajoie-Mazenc, Rémi Gence, Cyril Inard, Laetitia Ligat, Jean-Charles Faye, Gilles Favre

published 03 Nov 2014

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Mutations at Beta N265 in γ-Aminobutyric Acid Type A Receptors Alter Both Binding Affinity and Efficacy of Potent Anesthetics

Deirdre S. Stewart, David W. Pierce, Mayo Hotta, Alex T. Stern, Stuart A. Forman

published 27 Oct 2014

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Oncogenic GNAQ and GNA11 Mutations in Uveal Melanoma in Chinese

Xiaolin Xu, Wen Bin Wei, Bin Li, Fei Gao, Zhibao Zhang, Jost B. Jonas

published 03 Oct 2014

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Selection Pressure in Alternative Reading Frames

Katharina Mir, Steffen Schober

published 01 Oct 2014

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Investigation of the Josephin Domain Protein-Protein Interaction by Molecular Dynamics

Marco A. Deriu, Gianvito Grasso, Ginevra Licandro, Andrea Danani, Diego Gallo, Jack A. Tuszynski, Umberto Morbiducci

published 30 Sep 2014

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