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Stem cells

CRISPR/Cas9 gene editing in induced pluripotent stem cells to investigate the feline hypertrophic cardiomyopathy causing MYBPC3/R820W mutation

Luke C. Dutton, Jayesh Dudhia, Deborah J. Guest, David J. Connolly

published 10 Oct 2024

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A suboptimal OCT4-SOX2 binding site facilitates the naïve-state specific function of a Klf4 enhancer

Jack B. Waite, RuthMabel Boytz, Alexis R. Traeger, Torrey M. Lind, Koya Lumbao-Conradson, Sharon E. Torigoe

published 30 Sep 2024

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Single-nuclei transcriptome analysis of channel catfish spleen provides insight into the immunome of an aquaculture-relevant species

Johanna E. Aldersey, Miles D. Lange, Benjamin H. Beck, Jason W. Abernathy

published 26 Sep 2024

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Ultrastructural changes in cardiac and skeletal myoblasts following in vitro exposure to monensin, salinomycin, and lasalocid

Danielle Henn, Antonia V. Lensink, Christo J. Botha

published 25 Sep 2024

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CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting

Kelly Lim, Winnie L. Kan, Pramod C. Nair, Monika Kutyna, Angel F. Lopez, Timothy Hercus, David M. Ross, Steven Lane, Chun Yew Fong, Anna Brown, Agnes Yong, David Yeung, Timothy Hughes, Devendra Hiwase, Daniel Thomas

published 19 Sep 2024

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Carvedilol suppresses ryanodine receptor-dependent Ca²⁺ bursts in human neurons bearing PSEN1 variants found in early onset Alzheimer’s disease

Atsushi Hori, Haruka Inaba, Takashi Hato, Kimie Tanaka, Shoichi Sato, Mizuho Okamoto, Yuna Horiuchi, Faith Jessica Paran, Yoko Tabe, Shusuke Mori, Corina Rosales, Wado Akamatsu, Takashi Murayama, Nagomi Kurebayashi, Takashi Sakurai, Tomohiko Ai, Takashi Miida

published 22 Aug 2024

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Sporadic inclusion body myositis-derived myotube culture revealed muscle cell-autonomous expression profiles

Naoki Suzuki, Makoto Kanzaki, Masashi Koide, Rumiko Izumi, Ryo Fujita, Tadahisa Takahashi, Kazumi Ogawa, Yutaka Yabe, Masahiro Tsuchiya, Masako Suzuki, Ryuhei Harada, Akiyuki Ohno, Hiroya Ono, Naoko Nakamura, Kensuke Ikeda, Hitoshi Warita, Shion Osana, Yoshitsugu Oikawa, Takafumi Toyohara, Takaaki Abe, Muliang Rui, Satoru Ebihara, Ryoichi Nagatomi, Yoshihiro Hagiwara, Masashi Aoki

published 01 Aug 2024

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Selection of reference miRNAs for RT-qPCR assays in endometriosis menstrual blood-derived mesenchymal stem cells

Sabrina Yukari Santos Hacimoto, Ana Clara Lagazzi Cressoni, Lilian Eslaine Costa Mendes da Silva, Cristiana Carolina Padovan, Rui Alberto Ferriani, Júlio César Rosa-e-Silva, Juliana Meola

published 30 Jul 2024

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The differentiation of Lgr5+ progenitor cells on nanostructures of self-assembled silica beads

Wenjun Cai, Zhichun Huang, Baobin Sun, Ling Lu, Xiaoqiong Ding, Feng Tao

published 12 Jul 2024

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Preclinical safety assessment of modified gamma globin lentiviral vector-mediated autologous hematopoietic stem cell gene therapy for hemoglobinopathies

Mohammad Shadid, Archana Shrestha, Punam Malik

published 08 Jul 2024

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Immunosuppression in stem cell clinical trials of neural and retinal cell types: A systematic review

Shravan Gowrishankar, Matthew E. Smith, Nathan Creber, Jameel Muzaffar, Daniele Borsetto

published 05 Jul 2024

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Multielectrode array characterization of human induced pluripotent stem cell derived neurons in co-culture with primary human astrocytes

Maddie R. Lemieux, Bernhard Freigassner, Jessica L. Hanson, Zahra Thathey, Mark R. Opp, Charles A. Hoeffer, Christopher D. Link

published 25 Jun 2024

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Multiple isoforms of the Activin-like receptor baboon differentially regulate proliferation and conversion behaviors of neuroblasts and neuroepithelial cells in the Drosophila larval brain

Gyunghee G. Lee, Aidan J. Peterson, Myung-Jun Kim, Michael B. O’Connor, Jae H. Park

published 24 Jun 2024

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