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Stem cells

The effect of IL-1β inhibitor canakinumab (Ilaris®) on IL-6 production in human skeletal muscle cells

Anna Cordeiro-Santanach, Fiorella Morales, Maria del Carmen Parquet, Kitipong Uaesoontrachoon, Joyce Rowsell, Jordan Warford, Wilson Wu, Pia Elustondo, Eric P. Hoffman, Kanneboyina Nagaraju

published 06 Mar 2025

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Evaluating elexacaftor/tezacaftor/ivacaftor (ETI; Trikafta™) for treatment of patients with non-cystic fibrosis bronchiectasis (NCFBE): A clinical study protocol

Colin E. Swenson, William R. Hunt, Candela Manfredi, Diana J. Beltran, Jeong S. Hong, Brian R. Davis, Shingo Suzuki, Cristina Barillá, Andras Rab, Cynthia Chico, Joy Dangerfield, Ashleigh Streby, Erin Barton, Elizabeth M. Cox, Arlene A. Stecenko, Adrianna Westbrook, Rebecca Kapolka, Eric J. Sorscher

published 14 Feb 2025

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Loss of ING4 enhances hematopoietic regeneration in multipotent progenitor cells

Georgina A. Anderson, Marco Hernandez, Carlos Alfaro Quinde, Zanshé Thompson, Vera Binder-Blaser, Alison M. Taylor, Katie L. Kathrein

published 14 Feb 2025

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Exploring the combined effect of optimally controlled chemo-stem cell therapy on a fractional-order cancer model

Kaushik Dehingia, Sana Abdulkream Alharbi, Awatif Jahman Alqarni, Mounirah Areshi, Mona Alsulami, Reima Daher Alsemiry, Reem Allogmany, Homan Emadifar, Mati ur Rahman

published 13 Feb 2025

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Impact of developmental state, p53 status, and interferon signaling on glioblastoma cell response to radiation and temozolomide treatment

Artem Berezovsky, Oluwademilade Nuga, Indrani Datta, Kimberly Bergman, Thais Sabedot, Katherine Gurdziel, Susan Irtenkauf, Laura Hasselbach, Yuling Meng, Claudius Mueller, Emanuel F. . Petricoin III, Stephen Brown, Neeraja Purandare, Sidhesh Aras, Tom Mikkelsen, Laila Poisson, Houtan Noushmehr, Douglas Ruden, Ana C. deCarvalho

published 07 Feb 2025

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RORγt inverse agonists demonstrating a margin between inhibition of IL-17A and thymocyte apoptosis

Mia Collins, Rikard Pehrson, Hanna Grindebacke, Agnes Leffler, Marie Ramnegård, Helena Rannikmäe, Nina Krutrök, Linda Yrlid, Charlotte Pollard, Ian Dainty, Frank Narjes, Stefan von Berg, Antonio Llinas, Anna Malmberg, Jane McPheat, Eva Hansson, Elisabeth Bäck, Jenny Bernström, Thomas G. Hansson, David Keeling, Johan Jirholt

published 16 Jan 2025

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3D printing of different fibres towards HA/PCL scaffolding induces macrophage polarization and promotes osteogenic differentiation of BMSCs

Jiaxiang Song, Shuai Huang, Xitao Linghu, Hengpeng Wu, Zhenyu Wen, Xiang Li, Qiping Huang, Weikang Xu, Qingde Wa

published 13 Jan 2025

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Cellular therapy for the peripheral arterial disease treatment: Protocol for a systematic review and meta-analysis

Mónica Rodríguez-Valiente, Cristina Fuente-Mora, Javier Sánchez-Gálvez, Micaela Ortín-Pérez, Manuel Pardo-Ríos, José Manuel Sánchez-Sáez, Isac Davidson Santiago Fernandes Pimenta, Grasiela Piuvezam, Laura Ramos-Petersen

published 09 Jan 2025

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The role of the microbiota and metabolites in the treatment of pulmonary fibrosis with UC-MSCs: Integrating fecal metabolomics and 16S rDNA analysis

Yukai Luo, Shuang Zhou, Xiaojing Zhang, Yijian Lin, Jun Liu, Wenzhao Cheng, Yiming Zeng

published 09 Jan 2025

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Knockout of the ING5 epigenetic regulator confirms roles in stem cell maintenance and tumor suppression in vivo

Buthaina Al Shueili, Arthur Dantas, Etienne Mahe, Tak Ho Chu, Yang Yang, Elodie Labit, Eren Kutluberk, Nicolas Lasaleta, Anand Masson, Hiba Omairi, Kenichi Ito, Roman J. Krawetz, Rajiv Midha, Gregory Cairncross, Karl Riabowol

published 09 Jan 2025

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Next-generation sequencing protocol of hematopoietic stem cells (HSCs). Step-by-step overview and troubleshooting guide

Justyna Jarczak, Kamila Bujko, Katarzyna Brzeźniakiewicz-Janus, Mariusz Ratajczak, Magdalena Kucia

published 09 Jan 2025

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A NOTCH3 pathogenic variant influences osteogenesis and can be targeted by antisense oligonucleotides in induced pluripotent stem cells

Ernesto Canalis, Jungeun Yu, Lauren Schilling, Paymaan Jafar-nejad, Michele Carrer

published 03 Jan 2025

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The effects of secretome of umbilical cord mesenchymal stem cells on regeneration of sciatic nerve defects in Sprague dawley rats

Aryadi Kurniawan, Ismail Hadisoebroto Dilogo, Jeanne Adiwinata Pawitan, Wahyu Widodo, Ihsan Oesman, Ade Martinus

published 31 Dec 2024

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