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Stem cells

Stem cell therapy for female stress urinary incontinence: Results, limitations and lessons learned from a pilot clinical study

Rodrigo C. Souza, Maria A. T. Bortolini, Yasmin Melino, Juliana A. P. de Godoy, Kelen Alvarez, Denise De Oliveira, Andrea T. Kondo, Jose M. Kutner, Mariane Secco, Eder Zucconi, Natássia Vieira, Sérgio Podgaec, Rebecca S. P. Silva, Rodrigo A. Castro

published 27 Feb 2026

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A phase I clinical trial to evaluate the tolerability and safety of an allogeneic iPSC-derived iNKT cell and α-GalCer-pulsed autologous DC combination therapy for patients with recurrent and advanced head and neck cancer: A study protocol

Tomoya Kurokawa, Tomohisa Iinuma, Haruna Ebisu, Tomoha Yanagidaira, Yosuke Inaba, Tadami Fujiwara, Yoko Hattori, Tominaga Fukazawa, Takahiro Aoki, Haruhiko Koseki, Hideki Hanaoka, Toyoyuki Hanazawa, Shinichiro Motohashi

published 26 Feb 2026

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A damage-structured PDE model of stem cell hierarchies: The dual role of dedifferentiation in tissue homeostasis and aging

Louis Shuo Wang, Jiguang Yu, Zonghao Liu

published 24 Feb 2026

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Characterizing mitochondrial phenotypes and MERCS in aged human skeletal muscle myoblasts

Yufu Unten, Kazuaki Takafuji, Yumiko Masukagami, Isshin Shiiba, Keigo Horiuchi, Filip Husnik, Shigeru Yanagi, Norifumi Tateishi, Toshihide Suzuki

published 20 Feb 2026

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SHP2 improved Late-onset fetal growth restriction via modulating ROS/BRD4/PI3K/YAP/PIGF signaling induced angiogenesis

Fang Li, Yaqin Li, Wei Hao, Xuan Zhang, Xueyan Shen, Botao Yang, Wei Zhang, Liman Fu, Suyan Gu

published 13 Feb 2026

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A biologically constrained agent-based model of cancer stem cell dynamics with reinforcement learning-guided adaptive radiotherapy

Mina Lagzian, S. Ehsan Razavi, Reyhane Kardehi Moghaddam

published 05 Feb 2026

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Effect of stem cell therapies on tendon-bone healing after anterior cruciate ligament reconstruction in animal models: Protocol for a systematic review and meta-analysis

Shibo Zhao, Congcong Wang

published 04 Feb 2026

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Indistinguishable mitochondrial phenotypes after exposure of healthy myoblasts to myalgic encephalomyelitis/chronic fatigue syndrome or control serum

Audrey A. Ryback, Charles B. Hillier, Camila M. Loureiro, Chris P. Ponting, Caroline F. Dalton

published 03 Feb 2026

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Drospirenone promotes apoptosis in ectopic but inhibits proliferation in eutopic human endometrial stromal cells

Thanyarat Wongwananuruk, Somsin Petyim, Pawitra Suwannalert, Kittima Tungprasertpol, Supatra Klaymook

published 30 Jan 2026

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Functional role of THRAP3 in modulating thyroid hormone–mediated gene networks in C2C12 myotubes

Taku Fukushima, Sachi Kuse, Yuka Hasegawa, Taiju Fujioka, Takeshi Nikawa, Satoru Masubuchi, Iori Sakakibara

published 22 Jan 2026

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Effects of intermittent hypoxia on adipose-derived mesenchymal stem cells in protecting alveolar type II cells from injury

RuiYin Lai, SuHeng Chen, JunJie Cui, XiaoLong Liu, YuLan Li

published 21 Jan 2026

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Exosomes from bone marrow mesenchymal stem cells protect melanocytes under vitiligo-related conditions through induction of NRF2/HO1 expression

Xuecheng Sun, Bo Huang, Gaobo Ruan, Aie Xu

published 04 Dec 2025

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Use of a new micropattern tape method to detect chirality shifts in differentiating C2C12 cells

Qingkai Weng, Takashi Osaka, Hiroaki Onoe, Koki Yoshida, Yukiko Kuroda, Koichi Matsuo, Katsuhiro Kawaai

published 04 Dec 2025

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