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Sputum

Breaking barriers for TB elimination: A novel community-led strategy revolutionizing tuberculosis case finding and treatment support in Senapati District Manipur-A quasi-experimental pre-post study protocol

Arangba S, Singh S, Nagarajan K, Malaisamy M, Watson B, Muanching L, Mattoo SK, Elangbam V, Singh WS, Ngade D, Ngaopuo A, Lungnalii KT, Serto T, Pfoze P, Nair D, Vignes Anand S, Elizabeth RK, Mark PS, Hanah RN, Yonuo P, Percy S, Padma Priyadarshini C, Kaur H

published 03 Jul 2025

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Facilitators, barriers, and strategies for the implementation of peer-led tuberculosis active case finding among people who use drugs in Dar es Salaam, Tanzania

Lilian Tina Minja, Liana Monica Minja, Kilian Mlalama, Doreen Pamba, Jerry Hella, Samwel Likindikoki, Cassian Nyandindi, Jessie Mbwambo, Klaus Reither, Jennifer M. Belus

published 28 May 2025

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Nanopore-based targeted next-generation sequencing (tNGS): A versatile technology specialized in detecting low bacterial load clinical specimens

Chen Yang, Weiwei Gao, Yicheng Guo, Yi Zeng

published 27 May 2025

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The incremental value of tuberculosis detecting African giant pouched rats over Smear microscopy and Xpert MTB/RIF for Tanzanian TB detection

Tefera B. Agizew, Joseph Soka, Stephen Mwimanzi, Cynthia D. Fast, Gilbert Mwesiga, Nashon Edward, Marygiven Stephen, Rehema Kondo, Christophe Cox, Negussie Beyene

published 29 Apr 2025

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Active case finding using mobile vans with artificial intelligence aided radiology tests and sputum collection for rapid diagnostic tests to reduce tuberculosis prevalence among high-risk population in rural China: Protocol for a pragmatic trial

Xiaolin Wei, Dabin Liang, Zhitong Zhang, Kevin E. Thorpe, Lingyun Zhou, Jinming Zhao, Huifang Qin, Xiaoyan Liang, Zhezhe Cui, Yan Huang, Liwen Huang, Mei Lin

published 11 Apr 2025

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Prospective Analysis of urINe LAM to Eliminate NTM Sputum Screening (PAINLESS) study: Rationale and trial design for testing urine lipoarabinomannan as a marker of NTM lung infection in cystic fibrosis

Kara M. Calhoun, Emily Armantrout, Katie Poch, Silvia Caceres, Valerie K. Lovell, Marion Jones, Kenneth C. Malcolm, Brian Vestal, Emily Wheeler, Noel Rysavy, Jordan Manzer, Ibrahim Aboellail, Delphi Chatterjee, Jerry A. Nick

published 10 Mar 2025

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Performance of three diagnostic tests for tuberculosis among Human Immunodeficiency Virus (HIV) patients presenting to a health facility in an informal urban settlement in Nairobi, Kenya

Eunita A. Ochola, Marshal M. Mweu

published 30 Dec 2024

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The predictive value of heparin-binding protein for bacterial infections in patients with severe polytrauma

Li Li, Xiao-xi Tian, Gui-long Feng, Bing Chen

published 26 Dec 2024

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Prevalence of non-tuberculous mycobacteria among people with acid-fast positive presumptive tuberculosis in Mali

Aissata Boubakar Cisse, Anna S. Dean, Armand Van Deun, Jelle Keysers, Willem-Bram De Rijk, Mourad Gumusboga, Hawa Samake, Seydou Arama, Bassirou Diarra, Ibrahim Djilla, Fatoumata N. Coulibaly, Hawa Simpara, Mamadou Berthe, Khadidia Ouattara, Yacouba Toloba, Ibrehima Guindo, Bouke de Jong, Leen Rigouts

published 18 Dec 2024

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Laboratory validation of a simplified DNA extraction protocol followed by a portable qPCR detection of M. tuberculosis DNA suitable for point of care settings

Tainá dos Santos Soares, Graziele Lima Bello, Ianca Moraes dos Santos Petry, Maria Rita Castilho Nicola, Larissa Vitoria da Silva, Regina Bones Barcellos, Joana Morez Silvestri, Maria Lucia Rossetti, Alexandre Dias Tavares Costa

published 16 Dec 2024

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stilPCR increases the effective sequencing length of Illumina targeted next-generation sequencing

Jason D. Limberis, Roland J. Nagel, Soumitesh Chakravorty, Dena Block, Scott Dewell, Alina Nalyvayko, Zach Howard, Grant Theron, Rouxjeane Venter, John Z. Metcalfe

published 09 Dec 2024

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Bridging the “know-do” gap to improve active case finding for tuberculosis in India: A qualitative exploration into national tuberculosis elimination program staffs’ perspectives

Hemant Deepak Shewade, Prabhadevi Ravichandran, S. Kiran Pradeep, G. Kiruthika, Devika Shanmugasundaram, Joshua Chadwick, Swati Iyer, Aniket Chowdhury, Dheeraj Tumu, Amar N. Shah, Bhavin Vadera, Venkatesh Roddawar, Sanjay K. Mattoo, Kiran Rade, Raghuram Rao, Manoj V. Murhekar

published 04 Nov 2024

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Machine learning algorithms to predict treatment success for patients with pulmonary tuberculosis

Shaik Ahamed Fayaz, Lakshmanan Babu, Loganathan Paridayal, Mahalingam Vasantha, Palaniyandi Paramasivam, Karuppasamy Sundarakumar, Chinnaiyan Ponnuraja

published 16 Oct 2024

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