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Sphingolipids

Intraventricular Sialidase Administration Enhances GM1 Ganglioside Expression and Is Partially Neuroprotective in a Mouse Model of Parkinson’s Disease

Jay S. Schneider, Thomas N. Seyfried, Hyo-S. Choi, Sarah K. Kidd

published 02 Dec 2015

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Metabolic Conversion of Ceramides in HeLa Cells - A Cholesteryl Phosphocholine Delivery Approach

Matti A. Kjellberg, Max Lönnfors, J. Peter Slotte, Peter Mattjus

published 24 Nov 2015

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Sphingosine Kinase 2 and Ceramide Transport as Key Targets of the Natural Flavonoid Luteolin to Induce Apoptosis in Colon Cancer Cells

Loubna Abdel Hadi, Clara Di Vito, Giovanni Marfia, Anita Ferraretto, Cristina Tringali, Paola Viani, Laura Riboni

published 18 Nov 2015

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The Divergent CD8⁺ T Cell Adjuvant Properties of LT-IIb and LT-IIc, Two Type II Heat-Labile Enterotoxins, Are Conferred by Their Ganglioside-Binding B Subunits

John C. Hu, Christopher J. Greene, Natalie D. King-Lyons, Terry D. Connell

published 13 Nov 2015

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Serum Sphingolipid Variations Associate with Hepatic Decompensation and Survival in Patients with Cirrhosis

Georgios Grammatikos, Nerea Ferreiròs, Oliver Waidmann, Dimitra Bon, Sirkka Schroeter, Alexander Koch, Eva Herrmann, Stefan Zeuzem, Bernd Kronenberger, Josef Pfeilschifter

published 18 Sep 2015

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Visual Detection of Human Antibodies Using Sugar Chain-Immobilized Fluorescent Nanoparticles: Application as a Point of Care Diagnostic Tool for Guillain-Barré Syndrome

Hiroyuki Shinchi, Nobuhiro Yuki, Hideharu Ishida, Koichi Hirata, Masahiro Wakao, Yasuo Suda

published 17 Sep 2015

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The Molecular Mechanism of Amyloid β42 Peptide Toxicity: The Role of Sphingosine Kinase-1 and Mitochondrial Sirtuins

Magdalena Cieślik, Grzegorz A. Czapski, Joanna B. Strosznajder

published 03 Sep 2015

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A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung

Yidan D. Zhao, Lei Chu, Kathleen Lin, Elise Granton, Li Yin, Jenny Peng, Michael Hsin, Licun Wu, Amy Yu, Thomas Waddell, Shaf Keshavjee, John Granton, Marc de Perrot

published 28 Aug 2015

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Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice

André R. A. Marques, Jan Aten, Roelof Ottenhoff, Cindy P. A. A. van Roomen, Daniela Herrera Moro, Nike Claessen, María Fernanda Vinueza Veloz, Kuikui Zhou, Zhanmin Lin, Mina Mirzaian, Rolf G. Boot, Chris I. De Zeeuw, Herman S. Overkleeft, Yildiz Yildiz, Johannes M. F. G. Aerts

published 14 Aug 2015

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Lyso-Sulfatide Binds Factor Xa and Inhibits Thrombin Generation by the Prothrombinase Complex

Subramanian Yegneswaran, Yajnavalka Banerjee, José A. Fernández, Hiroshi Deguchi, John H. Griffin

published 11 Aug 2015

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Ligands Binding to Cell Surface Ganglioside GD2 Cause Src-Dependent Activation of N-Methyl-D-Aspartate Receptor Signaling and Changes in Cellular Morphology

Wenyong Tong, Mario Maira, Martin Gagnon, H. Uri Saragovi

published 07 Aug 2015

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GBM Derived Gangliosides Induce T Cell Apoptosis through Activation of the Caspase Cascade Involving Both the Extrinsic and the Intrinsic Pathway

Barun Mahata, Soumika Biswas, Patricia Rayman, Ali Chahlavi, Jennifer Ko, Ashish Bhattacharjee, Yu-Teh Li, Yuntao Li, Tanya Das, Gaurisankar Sa, Baisakhi Raychaudhuri, Michael A. Vogelbaum, Charles Tannenbaum, James H. Finke, Kaushik Biswas

published 30 Jul 2015

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Association of Anti-GT1a Antibodies with an Outbreak of Guillain-Barré Syndrome and Analysis of Ganglioside Mimicry in an Associated Campylobacter jejuni Strain

Maojun Zhang, Michel Gilbert, Nobuhiro Yuki, Fangfang Cao, Jianjun Li, Hongying Liu, Qun Li, Fanliang Meng, Jianzhong Zhang

published 21 Jul 2015

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