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Sphingolipids

Isolation and Functional Characterization of the Novel Clostridium botulinum Neurotoxin A8 Subtype

Skadi Kull, K. Melanie Schulz, [ ... ], Brigitte G. Dorner

Imbalance in Fatty-Acid-Chain Length of Gangliosides Triggers Alzheimer Amyloid Deposition in the Precuneus

Naoto Oikawa, Teruhiko Matsubara, [ ... ], Katsuhiko Yanagisawa

Activation of Transcription Factor Nrf2 Signalling by the Sphingosine Kinase Inhibitor SKI-II Is Mediated by the Formation of Keap1 Dimers

Nicolas Mercado, Yasuo Kizawa, [ ... ], Peter J. Barnes

Substrate Reduction Augments the Efficacy of Enzyme Therapy in a Mouse Model of Fabry Disease

John Marshall, Karen M. Ashe, [ ... ], Seng H. Cheng

AAV-Mediated Gene Delivery in Adult GM1-Gangliosidosis Mice Corrects Lysosomal Storage in CNS and Improves Survival

Rena C. Baek, Marike L. D. Broekman, [ ... ], Miguel Sena-Esteves

Hypertension Is Associated with Marked Alterations in Sphingolipid Biology: A Potential Role for Ceramide

Léon J. A. Spijkers, Rob F. P. van den Akker, [ ... ], Stephan L. M. Peters

Sphingosine Kinase-1 (SphK-1) Regulates Mycobacterium smegmatis Infection in Macrophages

Hridayesh Prakash, Anja Lüth, [ ... ], Burkhard Kleuser

Sphingolipid Metabolism Correlates with Cerebrospinal Fluid Beta Amyloid Levels in Alzheimer’s Disease

Alfred N. Fonteh, Cora Ormseth, [ ... ], Michael G. Harrington

Characterization of Isoenzyme-Selective Inhibitors of Human Sphingosine Kinases

Peng Gao, Yuri K. Peterson, Ryan A. Smith, Charles D. Smith

Chimeric Antibody c.8B6 to O-Acetyl-GD2 Mediates the Same Efficient Anti-Neuroblastoma Effects as Therapeutic ch14.18 Antibody to GD2 without Antibody Induced Allodynia

Mickaël Terme, Mylène Dorvillius, [ ... ], Stéphane Birklé

Glycerophospholipid and Sphingolipid Species and Mortality: The Ludwigshafen Risk and Cardiovascular Health (LURIC) Study

Alexander Sigruener, Marcus E. Kleber, [ ... ], Winfried Maerz

Elevated GM3 plasma concentration in idiopathic Parkinson’s disease: A lipidomic analysis

Robin B. Chan, Adler J. Perotte, [ ... ], Roy N. Alcalay

Binding, Conformational Transition and Dimerization of Amyloid-β Peptide on GM1-Containing Ternary Membrane: Insights from Molecular Dynamics Simulation

Moutusi Manna, Chaitali Mukhopadhyay

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