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Somatic mutation

Codon-level co-occurrences of germline variants and somatic mutations in cancer are rare but often lead to incorrect variant annotation and underestimated impact prediction

Amanda Koire, Young Won Kim, Jarey Wang, Panagiotis Katsonis, Haijing Jin, Olivier Lichtarge

published 28 Mar 2017

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Epigenomic annotation of noncoding mutations identifies mutated pathways in primary liver cancer

Rebecca F. Lowdon, Ting Wang

published 23 Mar 2017

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Integrated analysis of promoter mutation, methylation and expression of AKT1 gene in Chinese breast cancer patients

Jianfu Heng, Xinwu Guo, Wenhan Wu, Yue Wang, Guoli Li, Ming Chen, Limin Peng, Shouman Wang, Lizhong Dai, Lili Tang, Jun Wang

published 16 Mar 2017

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Highly sensitive detection of a HER2 12-base pair duplicated insertion mutation in lung cancer using the Eprobe-PCR method

Yoshiaki Takase, Kengo Usui, Kimihiro Shimizu, Yasumasa Kimura, Tatsuo Ichihara, Takahiro Ohkawa, Jun Atsumi, Yasuaki Enokida, Seshiru Nakazawa, Kai Obayashi, Yoichi Ohtaki, Toshiteru Nagashima, Yasumasa Mitani, Izumi Takeyoshi

published 02 Feb 2017

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Whole Exome Sequencing of Growing and Non-Growing Cutaneous Neurofibromas from a Single Patient with Neurofibromatosis Type 1

Daniel L. Faden, Saurabh Asthana, Tarik Tihan, Joseph DeRisi, Michel Kliot

published 18 Jan 2017

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Expression of APOBEC3B mRNA in Primary Breast Cancer of Japanese Women

Eriko Tokunaga, Nami Yamashita, Kimihiro Tanaka, Yuka Inoue, Sayuri Akiyoshi, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Yoshihiko Maehara

published 15 Dec 2016

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Genomic Profile of Chronic Lymphocytic Leukemia in Korea Identified by Targeted Sequencing

Jung-Ah Kim, Byungjin Hwang, Si Nae Park, Sunghoon Huh, Kyongok Im, Sungbin Choi, Hye Yoon Chung, JooRyung Huh, Eul-Ju Seo, Je-Hwan Lee, Duhee Bang, Dong Soon Lee

published 13 Dec 2016

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Genomic and Transcriptomic Alterations Associated with STAT3 Activation in Head and Neck Cancer

Noah D. Peyser, Kelsey Pendleton, William E. Gooding, Vivian W. Y. Lui, Daniel E. Johnson, Jennifer R. Grandis

published 17 Nov 2016

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Somatic Variations in Cervical Cancers in Indian Patients

Poulami Das, Akanksha Bansal, Sudha Narayan Rao, Kedar Deodhar, Umesh Mahantshetty, Shyam K. Shrivastava, Karthikeyan Sivaraman, Rita Mulherkar

published 09 Nov 2016

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A Systems Biology Comparison of Ovarian Cancers Implicates Putative Somatic Driver Mutations through Protein-Protein Interaction Models

Mary Qu Yang, Laura Elnitski

published 27 Oct 2016

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Accumulation of Deleterious Passenger Mutations Is Associated with the Progression of Hepatocellular Carcinoma

Magdalena A. Budzinska, Thomas Tu, William M. H. d’Avigdor, Geoffrey W. McCaughan, Fabio Luciani, Nicholas A. Shackel

published 15 Sep 2016

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Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients

Steffen Dietz, Uwe Schirmer, Clémentine Mercé, Nikolas von Bubnoff, Edgar Dahl, Michael Meister, Thomas Muley, Michael Thomas, Holger Sültmann

published 16 Aug 2016

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Prevalent Accumulation of Non-Optimal Codons through Somatic Mutations in Human Cancers

Xudong Wu, Guohui Li

published 11 Aug 2016

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