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Somatic mutation

Questioning the role of selected somatic PIK3C2B mutations in squamous non-small cell lung cancer oncogenesis

Marcus Kind, Jolanta Klukowska-Rötzler, Sabina Berezowska, Alexandre Arcaro, Roch-Philippe Charles

published 31 Oct 2017

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Idiopathic hypereosinophilia is clonal disorder? Clonality identified by targeted sequencing

Jee-Soo Lee, Heewon Seo, Kyongok Im, Si Nae Park, Sung-Min Kim, Eun Kyoung Lee, Jung-Ah Kim, Joon-hee Lee, Sunghoon Kwon, Miyoung Kim, Insong Koh, Seungwoo Hwang, Heung-Woo Park, Hye-Ryun Kang, Kyoung Soo Park, Ju Han Kim, Dong Soon Lee

published 31 Oct 2017

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Comprehensive benchmarking of SNV callers for highly admixed tumor data

Regina Bohnert, Sonia Vivas, Gunther Jansen

published 11 Oct 2017

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Unforeseen clonal evolution of tumor cell population in recurrent and metastatic dermatofibrosarcoma protuberans

Ensel Oh, Hae Min Jeong, Mi Jeong Kwon, Sang Yun Ha, Hyung Kyu Park, Ji-Young Song, Yu Jin Kim, Jong-Sun Choi, Eun Hee Lee, Jeeyun Lee, Yoon-La Choi, Young Kee Shin

published 04 Oct 2017

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Germline and somatic mutations in cortical malformations: Molecular defects in Argentinean patients with neuronal migration disorders

Dolores González-Morón, Sebastián Vishnopolska, Damián Consalvo, Nancy Medina, Marcelo Marti, Marta Córdoba, Cecilia Vazquez-Dusefante, Santiago Claverie, Sergio Alejandro Rodríguez-Quiroga, Patricia Vega, Walter Silva, Silvia Kochen, Marcelo Andrés Kauffman

published 27 Sep 2017

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KRAS and BRAF somatic mutations in colonic polyps and the risk of metachronous neoplasia

Miriam Juárez, Cecilia Egoavil, María Rodríguez-Soler, Eva Hernández-Illán, Carla Guarinos, Araceli García-Martínez, Cristina Alenda, Mar Giner-Calabuig, Oscar Murcia, Carolina Mangas, Artemio Payá, José R. Aparicio, Francisco A. Ruiz, Juan Martínez, Juan A. Casellas, José L. Soto, Pedro Zapater, Rodrigo Jover

published 27 Sep 2017

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Assessment of common somatic mutations of EGFR, KRAS, BRAF, NRAS in pulmonary non-small cell carcinoma using iPLEX^® HS, a new highly sensitive assay for the MassARRAY^® System

Bobbie C. Sutton, Ryan T. Birse, Kevin Maggert, Tammy Ray, Jessica Hobbs, Amobi Ezenekwe, Jason Kazmierczak, Michael Mosko, Joan Kish, Andrew Bullock, Zonggao Shi, M. Sharon Stack, Darryl Irwin

published 19 Sep 2017

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E2F1 somatic mutation within miRNA target site impairs gene regulation in colorectal cancer

Camila M. Lopes-Ramos, Bruna P. Barros, Fernanda C. Koyama, Paola A. Carpinetti, Julia Pezuk, Nayara T. S. Doimo, Angelita Habr-Gama, Rodrigo O. Perez, Raphael B. Parmigiani

published 13 Jul 2017

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Systematic genomic and translational efficiency studies of uveal melanoma

Chelsea Place Johnson, Ivana K. Kim, Bita Esmaeli, Ali Amin-Mansour, Daniel J. Treacy, Scott L. Carter, Eran Hodis, Nikhil Wagle, Sara Seepo, Xiaoxing Yu, Anne Marie Lane, Evangelos S. Gragoudas, Francisca Vazquez, Elizabeth Nickerson, Kristian Cibulskis, Aaron McKenna, Stacey B. Gabriel, Gad Getz, Eliezer M. Van Allen, Peter A. C. ‘t Hoen, Levi A. Garraway, Scott E. Woodman

published 08 Jun 2017

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Whole-genome sequencing of spermatocytic tumors provides insights into the mutational processes operating in the male germline

Eleni Giannoulatou, Geoffrey J. Maher, Zhihao Ding, Ad J. M. Gillis, Lambert C. J. Dorssers, Alexander Hoischen, Ewa Rajpert-De Meyts, WGS500 Consortium , Gilean McVean, Andrew O. M. Wilkie, Leendert H. J. Looijenga, Anne Goriely

published 22 May 2017

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Network based stratification of major cancers by integrating somatic mutation and gene expression data

Zongzhen He, Junying Zhang, Xiguo Yuan, Zhaowen Liu, Baobao Liu, Shouheng Tuo, Yajun Liu

published 16 May 2017

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Succinct workflows for circulating tumor cells after enrichment: From systematic counting to mutational profiling

Victor Chun-Lam Wong, Josephine Mun-Yee Ko, Chi-Tat Lam, Maria Li Lung

published 08 May 2017

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Ancient genes establish stress-induced mutation as a hallmark of cancer

Luis Cisneros, Kimberly J. Bussey, Adam J. Orr, Milica Miočević, Charles H. Lineweaver, Paul Davies

published 25 Apr 2017

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