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Somatic mutation

New methodology of TMB assessment from tissue and liquid biopsy in NSCLC

Ľudmila Křížová, Markéta Šafaříková, Marta Kalousová, Lucie Pfeiferová, Aleš Antonín Kuběna, Michal Vočka, Jan Ulrych, Věra Franková, Luboš Petruželka, Tomáš Zima, David Feltl

published 26 Sep 2022

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The genomic landscape of canine osteosarcoma cell lines reveals conserved structural complexity and pathway alterations

Kate Megquier, Jason Turner-Maier, Kathleen Morrill, Xue Li, Jeremy Johnson, Elinor K. Karlsson, Cheryl A. London, Heather L. Gardner

published 13 Sep 2022

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Whole exome sequencing reveals novel risk genes of pituitary neuroendocrine tumors

Raitis Peculis, Vita Rovite, Kaspars Megnis, Inga Balcere, Austra Breiksa, Jurijs Nazarovs, Janis Stukens, Ilze Konrade, Jelizaveta Sokolovska, Valdis Pirags, Janis Klovins

published 26 Aug 2022

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Genomic landscapes of canine splenic angiosarcoma (hemangiosarcoma) contain extensive heterogeneity within and between patients

Shukmei Wong, E. J. Ehrhart, Samuel Stewart, Victoria Zismann, Jacob Cawley, Rebecca Halperin, Natalia Briones, Keith Richter, Karthigayini Sivaprakasam, Nieves Perdigones, Tania Contente-Cuomo, Salvatore Facista, Jeffrey M. Trent, Muhammed Murtaza, Chand Khanna, William P. D. Hendricks

published 22 Jul 2022

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KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas

Meghan L. Rudd, Nancy F. Hansen, Xiaolu Zhang, Mary Ellen Urick, Suiyuan Zhang, Maria J. Merino, National Institutes of Health Intramural Sequencing Center Comparative Sequencing Program , James C. Mullikin, Lawrence C. Brody, Daphne W. Bell

published 26 Jan 2022

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Mutually exclusive mutation profiles define functionally related genes in muscle invasive bladder cancer

Ami G. Sangster, Robert J. Gooding, Andrew Garven, Hamid Ghaedi, David M. Berman, Scott K. Davey

published 24 Jan 2022

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CD8+ cell somatic mutations in multiple sclerosis patients and controls—Enrichment of mutations in STAT3 and other genes implicated in hematological malignancies

Miko Valori, Lilja Jansson, Pentti J. Tienari

published 07 Dec 2021

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Variant profiling of colorectal adenomas from three patients of two families with MSH3-related adenomatous polyposis

Claudia Perne, Sophia Peters, Maria Cartolano, Sukanya Horpaopan, Christina Grimm, Janine Altmüller, Anna K. Sommer, Axel M. Hillmer, Holger Thiele, Margarete Odenthal, Gabriela Möslein, Ronja Adam, Sugirthan Sivalingam, Jutta Kirfel, Michal R. Schweiger, Martin Peifer, Isabel Spier, Stefan Aretz

published 29 Nov 2021

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Longitudinal detection of somatic mutations in saliva and plasma for the surveillance of oral squamous cell carcinomas

Ying Cui, Hae-Suk Kim, Eunae Sandra Cho, Dawool Han, Jung Ah Park, Ju Yeong Park, Woong Nam, Hyung Jun Kim, In-Ho Cha, Yong Hoon Cha

published 03 Sep 2021

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Framing the potential of public frameshift peptides as immunotherapy targets in colon cancer

Ide T. Spaanderman, Fleur S. Peters, Aldo Jongejan, Egbert J. W. Redeker, Cornelis J. A. Punt, Adriaan D. Bins

published 28 Jun 2021

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Prognostic value of integrated cytogenetic, somatic variation, and copy number variation analyses in Korean patients with newly diagnosed multiple myeloma

Nuri Lee, Sung-Min Kim, Youngeun Lee, Dajeong Jeong, Jiwon Yun, Sohee Ryu, Sung-Soo Yoon, Yong-Oon Ahn, Sang Mee Hwang, Dong Soon Lee

published 05 Feb 2021

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Association of a novel endometrial cancer biomarker panel with prognostic risk, platinum insensitivity, and targetable therapeutic options

Jesus Gonzalez Bosquet, Qing Zhang, William A. Cliby, Jamie N. Bakkum-Gamez, Ling Cen, Sean C. Dowdy, Mark E. Sherman, S. John Weroha, Amy C. Clayton, Benjamin R. Kipp, Kevin C. Halling, Fergus J. Couch, Karl C. Podratz

published 27 Jan 2021

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Two-step multi-omics modelling of drug sensitivity in cancer cell lines to identify driving mechanisms

Nina Kusch, Andreas Schuppert

published 23 Nov 2020

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