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Somatic mutation

Assessing Matched Normal and Tumor Pairs in Next-Generation Sequencing Studies

Liang Goh, Geng Bo Chen, Ioana Cutcutache, Benjamin Low, Bin Tean Teh, Steve Rozen, Patrick Tan

published 18 Mar 2011

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Somatic Mutation Profiles of MSI and MSS Colorectal Cancer Identified by Whole Exome Next Generation Sequencing and Bioinformatics Analysis

Bernd Timmermann, Martin Kerick, Christina Roehr, Axel Fischer, Melanie Isau, Stefan T. Boerno, Andrea Wunderlich, Christian Barmeyer, Petra Seemann, Jana Koenig, Michael Lappe, Andreas W. Kuss, Masoud Garshasbi, Lars Bertram, Kathrin Trappe, Martin Werber, Bernhard G. Herrmann, Kurt Zatloukal, Hans Lehrach, Michal R. Schweiger

published 22 Dec 2010

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Exploring the Link between Germline and Somatic Genetic Alterations in Breast Carcinogenesis

Núria Bonifaci, Bohdan Górski, Bartlomiej Masojć, Dominika Wokołorczyk, Anna Jakubowska, Tadeusz Dębniak, Antoni Berenguer, Jordi Serra Musach, Joan Brunet, Joaquín Dopazo, Steven A. Narod, Jan Lubiński, Conxi Lázaro, Cezary Cybulski, Miguel Angel Pujana

published 22 Nov 2010

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Somatic Point Mutations in mtDNA Control Region Are Influenced by Genetic Background and Associated with Healthy Aging: A GEHA Study

Giuseppina Rose, Giuseppe Romeo, Serena Dato, Paolina Crocco, Amalia C. Bruni, Antti Hervonen, Kari Majamaa, Federica Sevini, Claudio Franceschi, Giuseppe Passarino, the GEHA Project Consortium

published 14 Oct 2010

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Frequent MAGE Mutations in Human Melanoma

Otavia L. Caballero, Qi Zhao, Donata Rimoldi, Brian J. Stevenson, Suzanne Svobodová, Sylvie Devalle, Ute F. Röhrig, Anna Pagotto, Olivier Michielin, Daniel Speiser, Jedd D. Wolchok, Cailian Liu, Tanja Pejovic, Kunle Odunsi, Francis Brasseur, Benoit J. Van den Eynde, Lloyd J. Old, Xin Lu, Jonathan Cebon, Robert L. Strausberg, Andrew J. Simpson

published 16 Sep 2010

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Mutational Profiling of Kinases in Human Tumours of Pancreatic Origin Identifies Candidate Cancer Genes in Ductal and Ampulla of Vater Carcinomas

Vincenzo Corbo, Rossana Ritelli, Stefano Barbi, Niccola Funel, Daniela Campani, Alberto Bardelli, Aldo Scarpa

published 08 Sep 2010

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Risk Factors for Colorectal Cancer in Patients with Multiple Serrated Polyps: A Cross-Sectional Case Series from Genetics Clinics

Daniel D. Buchanan, Kevin Sweet, Musa Drini, Mark A. Jenkins, Aung Ko Win, Dallas R. English, Michael D. Walsh, Mark Clendenning, Diane M. McKeone, Rhiannon J. Walters, Aedan Roberts, Sally-Ann Pearson, Erika Pavluk, John L. Hopper, Michael R. Gattas, Jack Goldblatt, Jill George, Graeme K. Suthers, Kerry D. Phillips, Sonja Woodall, Julie Arnold, Kathy Tucker, Amanda Muir, Michael Field, Sian Greening, Steven Gallinger, Renee Perrier, John A. Baron, John D. Potter, Robert Haile, Wendy Frankel, Albert de la Chapelle, Finlay Macrae, Christophe Rosty, Neal I. Walker, Susan Parry, Joanne P. Young

published 16 Jul 2010

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Structural and Functional Restraints on the Occurrence of Single Amino Acid Variations in Human Proteins

Sungsam Gong, Tom L. Blundell

published 12 Feb 2010

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CBL Is Frequently Altered in Lung Cancers: Its Relationship to Mutations in MET and EGFR Tyrosine Kinases

Yi-Hung Carol Tan, Soundararajan Krishnaswamy, Suvobroto Nandi, Rajani Kanteti, Sapana Vora, Kenan Onel, Rifat Hasina, Fang-Yi Lo, Essam El-Hashani, Gustavo Cervantes, Matthew Robinson, Stephen C. Kales, Stanley Lipkowitz, Theodore Karrison, Martin Sattler, Everett E. Vokes, Yi-Ching Wang, Ravi Salgia

published 29 Jan 2010

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Bi-Directional SIFT Predicts a Subset of Activating Mutations

William Lee, Yan Zhang, Kiran Mukhyala, Robert A. Lazarus, Zemin Zhang

published 14 Dec 2009

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Chimerism in Wild Adult Populations of the Broadcast Spawning Coral Acropora millepora on the Great Barrier Reef

Eneour Puill-Stephan, Bette L. Willis, Lynne van Herwerden, Madeleine J. H. van Oppen

published 04 Nov 2009

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Screening for Microsatellite Instability Identifies Frequent 3′-Untranslated Region Mutation of the RB1-Inducible Coiled-Coil 1 Gene in Colon Tumors

Bogdan C. Paun, Yulan Cheng, Barbara A. Leggett, Joanne Young, Stephen J. Meltzer, Yuriko Mori

published 02 Nov 2009

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Mutator Mutations Enhance Tumorigenic Efficiency across Fitness Landscapes

Robert A. Beckman

published 10 Jun 2009

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