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Solubility

Development and in vitro characterization of a humanized scFv against fungal infections

Tomas Di Mambro, Tania Vanzolini, Marzia Bianchi, Rita Crinelli, Barbara Canonico, Filippo Tasini, Michele Menotta, Mauro Magnani

published 31 Oct 2022

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Identification of natural cytochalasins as leads for neglected tropical diseases drug discovery

Marilia Valli, Julia Medeiros Souza, Rafael Consolin Chelucci, Carolina Rabal Biasetto, Angela Regina Araujo, Vanderlan da Silva Bolzani, Adriano Defini Andricopulo

published 03 Oct 2022

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Solubility affects IL-1β-producing activity of the synthetic candidalysin peptide

Taiki Mori, Hideo Kataoka, Gen Tanabe, Takeshi Into

published 30 Aug 2022

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Fe³⁺ opposes the 1,25(OH)₂D₃-induced calcium transport across intestinal epithelium-like Caco-2 monolayer in the presence or absence of ascorbic acid

Sukpapohn Phummisutthigoon, Kornkamon Lertsuwan, Nattapon Panupinthu, Ratchaneevan Aeimlapa, Jarinthorn Teerapornpuntakit, Wasutorn Chankamngoen, Jirawan Thongbunchoo, Narattaphol Charoenphandhu, Kannikar Wongdee

published 30 Aug 2022

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13-amino derivatives of dehydrocostus lactone display greatly enhanced selective toxicity against breast cancer cells and improved binding energies to protein kinases in silico

Douglas Kemboi, Moses K. Langat, Xavier Siwe-Noundou, Tendamudzimu Tshiwawa, Rui W. M. Krause, Candace Davison, Christie Jane Smit, Jo-Anne de la Mare, Vuyelwa Jacqueline Tembu

published 23 Aug 2022

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Fusion with heat-resistant obscure (Hero) proteins have the potential to improve the molecular property of recombinant proteins

Eri Morimoto, Kotaro Tsuboyama, Yukihide Tomari

published 17 Jun 2022

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Pre-clinical evaluation of LASSBio-1491: From in vitro pharmacokinetic study to in vivo leishmanicidal activity

Aline Cavalcanti de Queiroz, Gisele Barbosa, Victória Regina Thomaz de Oliveira, Hélio de Mattos Alves, Marina Amaral Alves, Vanessa Carregaro, João Santana da Silva, Eliezer Jesus Barreiro, Magna Suzana Alexandre-Moreira, Lidia Moreira Lima

published 06 Jun 2022

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Potential of antiviral peptide-based SARS-CoV-2 inactivators to combat COVID-19

Arun Bahadur Gurung, Mohammad Ajmal Ali, Joongku Lee, Mohamed El-Zaidy, Reem M. Aljowaie, Saeedah M. Almutairi

published 03 Jun 2022

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Effects of arsenic on the topology and solubility of promyelocytic leukemia (PML)-nuclear bodies

Seishiro Hirano, Osamu Udagawa

published 20 May 2022

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Nano-hydroxyapatite improves intestinal absorption of acetazolamide (BCS Class IV drug)–but how?

Kenichi Kaneko, Ryosuke Miyasaka, Roslyn Hayman

published 19 May 2022

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Comparative expression of soluble, active human kinases in specialized bacterial strains

Allison Sunderhaus, Ramsha Imran, Elanzou Enoh, Adesola Adedeji, Taiye Obafemi, May H. Abdel Aziz

published 19 Apr 2022

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Improved solubility and corneal permeation of PEGylated curcumin complex used for the treatment of ophthalmic bacterial infections

Muhammad Hanif, Nabeela Ameer, Qurat-ul-Ain Ahmad, Mubashir Aziz, Khalid Mahmood, Nasreen Ramzan, Hafiz Muhammad Abdur Rahman

published 07 Apr 2022

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Long-term stability of clopidogrel solid dispersions—Importance of in vitro dissolution test

Ehlimana Osmanović Omerdić, Larisa Alagić-Džambić, Marko Krstić, Maja Pašić-Kulenović, Đorđe Medarević, Branka Ivković, Dragana Vasiljević

published 04 Apr 2022

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