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Solid state physics

Understanding the Role of the Josephin Domain in the PolyUb Binding and Cleavage Properties of Ataxin-3

Giuseppe Nicastro, Sokol V. Todi, Ezgi Karaca, Alexandre M. J. J. Bonvin, Henry L. Paulson, Annalisa Pastore

published 26 Aug 2010

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Insights into the Binding of Phenyltiocarbamide (PTC) Agonist to Its Target Human TAS2R38 Bitter Receptor

Xevi Biarnés, Alessandro Marchiori, Alejandro Giorgetti, Carmela Lanzara, Paolo Gasparini, Paolo Carloni, Stephan Born, Anne Brockhoff, Maik Behrens, Wolfgang Meyerhof

published 25 Aug 2010

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Structure of the Altitude Adapted Hemoglobin of Guinea Pig in the R2-State

Bruno Pairet, Elmar Jaenicke

published 24 Aug 2010

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Insights into the Mechanism of Ligand Binding to Octopine Dehydrogenase from Pecten maximus by NMR and Crystallography

Sander H. J. Smits, Tatu Meyer, Andre Mueller, Nadine van Os, Matthias Stoldt, Dieter Willbold, Lutz Schmitt, Manfred K. Grieshaber

published 19 Aug 2010

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Structural Insights into the Quinolone Resistance Mechanism of Mycobacterium tuberculosis DNA Gyrase

Jérémie Piton, Stéphanie Petrella, Marc Delarue, Gwénaëlle André-Leroux, Vincent Jarlier, Alexandra Aubry, Claudine Mayer

published 18 Aug 2010

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Optimized Hydrophobic Interactions and Hydrogen Bonding at the Target-Ligand Interface Leads the Pathways of Drug-Designing

Rohan Patil, Suranjana Das, Ashley Stanley, Lumbani Yadav, Akulapalli Sudhakar, Ashok K. Varma

published 16 Aug 2010

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Integrating Ion Mobility Mass Spectrometry with Molecular Modelling to Determine the Architecture of Multiprotein Complexes

Argyris Politis, Ah Young Park, Suk-Joon Hyung, Daniel Barsky, Brandon T. Ruotolo, Carol V. Robinson

published 10 Aug 2010

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Insights in 17β-HSD1 Enzyme Kinetics and Ligand Binding by Dynamic Motion Investigation

Matthias Negri, Maurizio Recanatini, Rolf W. Hartmann

published 10 Aug 2010

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Structural Comparison of Human Mammalian Ste20-Like Kinases

Christopher J. Record, Apirat Chaikuad, Peter Rellos, Sanjan Das, Ashley C. W. Pike, Oleg Fedorov, Brian D. Marsden, Stefan Knapp, Wen Hwa Lee

published 06 Aug 2010

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Dynamic Subunit Exchange and the Regulation of Microtubule Assembly by the Stress Response Protein Human αB Crystallin

Scott A. Houck, John I. Clark

published 26 Jul 2010

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Identification of the Rheumatoid Arthritis Shared Epitope Binding Site on Calreticulin

Song Ling, Andrew Cheng, Paul Pumpens, Marek Michalak, Joseph Holoshitz

published 22 Jul 2010

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Fluorescent Fusion Proteins of Soluble Guanylyl Cyclase Indicate Proximity of the Heme Nitric Oxide Domain and Catalytic Domain

Tobias Haase, Nadine Haase, Jan Robert Kraehling, Soenke Behrends

published 15 Jul 2010

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Modeling the Ternary Complex TCR-Vβ/CollagenII(261–273)/HLA-DR4 Associated with Rheumatoid Arthritis

Maria Cristina De Rosa, Bruno Giardina, Caterina Bianchi, Cristiana Carelli Alinovi, Davide Pirolli, Gianfranco Ferraccioli, Maria De Santis, Gabriele Di Sante, Francesco Ria

published 14 Jul 2010

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