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Solid state physics

Site-Directed Mutations and the Polymorphic Variant Ala160Thr in the Human Thromboxane Receptor Uncover a Structural Role for Transmembrane Helix 4

Raja Chakraborty, Sai Prasad Pydi, Scott Gleim, Shyamala Dakshinamurti, John Hwa, Prashen Chelikani

published 17 Jan 2012

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A Model for the Ultrastructure of Bone Based on Electron Microscopy of Ion-Milled Sections

Elizabeth A. McNally, Henry P. Schwarcz, Gianluigi A. Botton, A. Larry Arsenault

published 17 Jan 2012

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Crystal Structure of a Human Single Domain Antibody Dimer Formed through V_H-V_H Non-Covalent Interactions

Toya Nath Baral, Shi-Yu Chao, Shenghua Li, Jamshid Tanha, Mehdi Arbabi-Ghahroudi, Jianbing Zhang, Shuying Wang

published 12 Jan 2012

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Human PAPS Synthase Isoforms Are Dynamically Regulated Enzymes with Access to Nucleus and Cytoplasm

Elisabeth Schröder, Lena Gebel, Andrey A. Eremeev, Jessica Morgner, Daniel Grum, Shirley K. Knauer, Peter Bayer, Jonathan W. Mueller

published 05 Jan 2012

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Hydroxybenzothiazoles as New Nonsteroidal Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1)

Alessandro Spadaro, Matthias Negri, Sandrine Marchais-Oberwinkler, Emmanuel Bey, Martin Frotscher

published 05 Jan 2012

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A-Site Residues Move Independently from P-Site Residues in all-Atom Molecular Dynamics Simulations of the 70S Bacterial Ribosome

Relly Brandman, Yigal Brandman, Vijay S. Pande

published 03 Jan 2012

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Molecular Mechanisms of Bortezomib Resistant Adenocarcinoma Cells

Erika Suzuki, Susan Demo, Edgar Deu, Jonathan Keats, Shirin Arastu-Kapur, P. Leif Bergsagel, Mark K. Bennett, Christopher J. Kirk

published 22 Dec 2011

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The Plasmodium falciparum Malaria M1 Alanyl Aminopeptidase (PfA-M1): Insights of Catalytic Mechanism and Function from MD Simulations

Peter M. Jones, Mark W. Robinson, John P. Dalton, Anthony M. George

published 21 Dec 2011

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N-glycans of Human Protein C Inhibitor: Tissue-Specific Expression and Function

Wei Sun, Paola Grassi, Åke Engström, Sanjeewani Sooriyaarachchi, Wimal Ubhayasekera, Julius Hreinsson, Kjell Wånggren, Gary F. Clark, Anne Dell, Sophia Schedin-Weiss

published 19 Dec 2011

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A Novel N-Acetylglutamate Synthase Architecture Revealed by the Crystal Structure of the Bifunctional Enzyme from Maricaulis maris

Dashuang Shi, Yongdong Li, Juan Cabrera-Luque, Zhongmin Jin, Xiaolin Yu, Gengxiang Zhao, Nantaporn Haskins, Norma M. Allewell, Mendel Tuchman

published 12 Dec 2011

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Characterization of Pellicle Inhibition in Gluconacetobacter xylinus 53582 by a Small Molecule, Pellicin, Identified by a Chemical Genetics Screen

Janice L. Strap, Andrew Latos, Isaac Shim, Dario T. Bonetta

published 09 Dec 2011

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Protein 3D Structure Computed from Evolutionary Sequence Variation

Debora S. Marks, Lucy J. Colwell, Robert Sheridan, Thomas A. Hopf, Andrea Pagnani, Riccardo Zecchina, Chris Sander

published 07 Dec 2011

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Structural Studies of β-Carbonic Anhydrase from the Green Alga Coccomyxa: Inhibitor Complexes with Anions and Acetazolamide

Shenghua Huang, Tobias Hainzl, Christin Grundström, Cecilia Forsman, Göran Samuelsson, A. Elisabeth Sauer-Eriksson

published 05 Dec 2011

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