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Solid state physics

Single Nucleotide Polymorphisms of Human STING Can Affect Innate Immune Response to Cyclic Dinucleotides

Guanghui Yi, Volker P. Brendel, Chang Shu, Pingwei Li, Satheesh Palanathan, C. Cheng Kao

published 21 Oct 2013

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Atomic-Accuracy Prediction of Protein Loop Structures through an RNA-Inspired Ansatz

Rhiju Das

published 21 Oct 2013

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Discovery and Computer Aided Potency Optimization of a Novel Class of Small Molecule CXCR4 Antagonists

Victoria Vinader, Djevdet S. Ahmet, Mohaned S. Ahmed, Laurence H. Patterson, Kamyar Afarinkia

published 18 Oct 2013

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The Conserved C-Terminus of the PcrA/UvrD Helicase Interacts Directly with RNA Polymerase

Emma J. Gwynn, Abigail J. Smith, Colin P. Guy, Nigel J. Savery, Peter McGlynn, Mark S. Dillingham

published 16 Oct 2013

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Dolutegravir Interactions with HIV-1 Integrase-DNA: Structural Rationale for Drug Resistance and Dissociation Kinetics

Felix DeAnda, Kendra E. Hightower, Robert T. Nolte, Kazunari Hattori, Tomokazu Yoshinaga, Takashi Kawasuji, Mark R. Underwood

published 16 Oct 2013

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Structural and Mechanistic Insight into DNA Unwinding by Deinococcus radiodurans UvrD

Meike Stelter, Samira Acajjaoui, Sean McSweeney, Joanna Timmins

published 15 Oct 2013

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Protein-Protein Interactions as a Strategy towards Protein-Specific Drug Design: The Example of Ataxin-1

Cesira de Chiara, Rajesh P. Menon, Geoff Kelly, Annalisa Pastore

published 14 Oct 2013

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Molecular Characterization of Monoclonal Antibodies that Inhibit Acetylcholinesterase by Targeting the Peripheral Site and Backdoor Region

Yves Bourne, Ludovic Renault, Sosthène Essono, Grégoire Mondielli, Patricia Lamourette, Didier Boquet, Jacques Grassi, Pascale Marchot

published 11 Oct 2013

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Comparative Analysis of the Tyr-Kinases CapB1 and CapB2 Fused to Their Cognate Modulators CapA1 and CapA2 from Staphylococcus aureus

Jakub Gruszczyk, Vanesa Olivares-Illana, Julien Nourikyan, Aurore Fleurie, Emmanuelle Béchet, Virginie Gueguen-Chaignon, Céline Freton, Magali Aumont-Nicaise, Solange Moréra, Christophe Grangeasse, Sylvie Nessler

published 11 Oct 2013

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A Tuneable Switch for Controlling Environmental Degradation of Bioplastics: Addition of Isothiazolinone to Polyhydroxyalkanoates

Catherine Anne Woolnough, Lachlan Hartley Yee, Timothy Stuart Charlton, Leslie John Ray Foster

published 11 Oct 2013

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HIV’s Nef Interacts with β-Catenin of the Wnt Signaling Pathway in HEK293 Cells

Keren Weiser, Meredith Barton, Dafna Gershoony, Ramanuj DasGupta, Timothy Cardozo

published 10 Oct 2013

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Molecular Dynamics Simulations of DNA-Free and DNA-Bound TAL Effectors

Hua Wan, Jian-ping Hu, Kang-shun Li, Xu-hong Tian, Shan Chang

published 10 Oct 2013

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Electrostatic Similarities between Protein and Small Molecule Ligands Facilitate the Design of Protein-Protein Interaction Inhibitors

Arnout Voet, Francois Berenger, Kam Y. J. Zhang

published 10 Oct 2013

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