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Senescence

Mechanistic insights into the anti-aging effects of Crocus sativus in a D-Gal-induced in vitro neural senescence model

Vanessa Castelli, Patrizia Cesare, Erjola Bej, Michele d’Angelo, Anna Rita Volpe

published 16 Jul 2025

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Umbilical cord mesenchymal stem cell exosomal miR-143-3p delays endothelial cell senescence through targeting COX-2

Zhi-peng Yang, Shui-hong Lu, Yan-hong Pan, Zhao-fu Liao, Yi-tuan Xie, Heng Li, Yu-lan Zhou, Zhen-can Shi, Yun-fei Qu, Zhu-guo Wu, Chongxiang Xiong, Xing-dong Xiong

published 11 Jul 2025

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PDRN prevents SIRT1 degradation by attenuating autophagy during skin aging

Jingjing Chen, Fanshan Qiu, Jianfeng Shi, Wei Huang, Chenyu Zhao, Qianqian Han

published 09 May 2025

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Taurine is a potential therapy for rheumatoid arthritis via targeting FOXO3 through cellular senescence and autophagy

Qingcong Zheng, Rongjie Lin, Zhechen Li, Qingzhu Zheng, Weihong Xu

published 16 Apr 2025

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Aging aggravates cognitive dysfunction in spontaneously hypertensive rats by inducing cerebral microvascular endothelial dysfunction

Mei Wu, Dandan Li, Feng Qiu, Huifang Nie, Rui Fang, Ziyan Zhong, Hui Yang, Xiaoyuan Lin, Xiangyuan Wang, Hongbo Wen, Lijun Gong, Pan Meng

published 13 Mar 2025

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Analysis of cellular senescence-related genes in calcified aortic valve disease and the potential therapeutic role of β-Carotene

Yijing Tao, Chengjie Gao, Juan Wang, Qiyin Zhang, Zhisong Wang, Leng Han, Donglai Cao, Qianwen Yao

published 10 Mar 2025

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Cellular senescence-associated genes in rheumatoid arthritis: Identification and functional analysis

You Ao, Qing Lan, Tianhua Yu, Zhichao Wang, Jing Zhang

published 16 Jan 2025

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Age-related lung changes linked to altered lysosomal protease profile, histology, and ultrastructure

Mohammed Aufy, Mahmoud Abd-Elkareem, Medina Mustafic, Mostafa A. Abdel-Maksoud, Ali Hakamy, Veronika Baresova, Akram A. Alfuraydi, Mahmoud Ashry, Jana Lubec, Ayman S. Amer, Christian R. Studenik, Ahmed M. Hussein, Mohamed H. Kotob

published 20 Dec 2024

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Deciphering the impact of senescence in kidney transplant rejection: An integrative machine learning and multi-omics analysis via bulk and single-cell RNA sequencing

Xihao Shen, Jiyue Wu, Feilong Zhang, Qing Bi, Zejia Sun, Wei Wang

published 27 Nov 2024

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Osteoporosis induced by cellular senescence: A mathematical model

Nourridine Siewe, Avner Friedman

published 28 May 2024

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Role of maraviroc and/or rapamycin in the liver of IL10 KO mice with frailty syndrome

Laura Pérez-Martínez, Lourdes Romero, Eva M. Verdugo-Sivianes, Sandra Muñoz-Galván, Susana Rubio-Mediavilla, Ana Amiama-Roig, Amancio Carnero, José-Ramón Blanco

published 10 Jan 2024

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β-nicotinamide mononucleotide rescues the quality of aged oocyte and improves subsequent embryo development in pigs

Leyi Li, Qinghe Han, Yurong Chen, Meng Zhang, Luyao Wang, Xinglan An, Sheng Zhang, Yanhui Zhai, Xiangpeng Dai, Bo Tang, Ziyi Li, Guanghong Xie

published 05 Oct 2023

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Integrated physiological and metabolomic analyses reveal changes during the natural senescence of Quercus mongolica leaves

Yangchen Yuan, Weiqiang Zhang, Jiushuai Pang, Miaomiao Zhou, Jianying Liu, Jin Zhao, Jinming Sui, Dazhuang Huang, Minsheng Yang

published 23 Aug 2023

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