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Reverse transcriptase inhibitors

Raltegravir Non-Inferior to Nucleoside Based Regimens in SECOND-LINE Therapy with Lopinavir/Ritonavir over 96 Weeks: A Randomised Open Label Study for the Treatment Of HIV-1 Infection

Janaki Amin, Mark A. Boyd, Nagalingeswaran Kumarasamy, Cecilia L. Moore, Marcello H. Losso, Chidi A. Nwizu, Lerato Mohapi, Stephen J. Kerr, Annette H. Sohn, Hedy Teppler, Boris Renjifo, Jean-Michel Molina, Sean Emery, David A. Cooper

published 27 Feb 2015

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High Prevalence of the K65R Mutation in HIV-1 Subtype C Infected Patients Failing Tenofovir-Based First-Line Regimens in South Africa

Lindiwe Skhosana, Kim Steegen, Michelle Bronze, Azwidowi Lukhwareni, Esrom Letsoalo, Maria A. Papathanasopoulos, Sergio C. Carmona, Wendy S. Stevens

published 06 Feb 2015

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No Difference in the Rate of Change in Telomere Length or Telomerase Activity in HIV-Infected Patients after Three Years of Darunavir/Ritonavir with and without Nucleoside Analogues in the MONET Trial

Ajantha Solomon, Surekha Tennakoon, Edwin Leeansyah, Jose Arribas, Andrew Hill, Yvon Van Delft, Christiane Moecklinghoff, Sharon R. Lewin

published 04 Nov 2014

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Induction with Lopinavir-Based Treatment Followed by Switch to Nevirapine-Based Regimen versus Non-Nucleoside Reverse Transcriptase Inhibitors-Based Treatment for First Line Antiretroviral Therapy in HIV Infected Children Three Years and Older

Gerardo Alvarez-Uria, Raghavakalyan Pakam, Praveen Kumar Naik, Manoranjan Midde

published 18 Sep 2014

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Trends in First-Line Antiretroviral Therapy in Asia: Results from the TREAT Asia HIV Observational Database

David Charles Boettiger, Stephen Kerr, Rossana Ditangco, Tuti Parwati Merati, Thuy Thi Thanh Pham, Romanee Chaiwarith, Sasisopin Kiertiburanakul, Chung Ki Patrick Li, Nagalingeswaran Kumarasamy, Saphonn Vonthanak, Christopher Lee, Nguyen Van Kinh, Sanjay Pujari, Wing Wai Wong, Adeeba Kamarulzaman, Fujie Zhang, Evy Yunihastuti, Jun Yong Choi, Shinichi Oka, Oon Tek Ng, Pacharee Kantipong, Mahiran Mustafa, Winai Ratanasuwan, Annette Sohn, Matthew Law

published 03 Sep 2014

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Psychosocial Predictors of Non-Adherence and Treatment Failure in a Large Scale Multi-National Trial of Antiretroviral Therapy for HIV: Data from the ACTG A5175/PEARLS Trial

Steven A. Safren, Katie B. Biello, Laura Smeaton, Matthew J. Mimiaga, Ann Walawander, Javier R. Lama, Aadia Rana, Mulinda Nyirenda, Virginia M. Kayoyo, Wadzanai Samaneka, Anjali Joglekar, David Celentano, Ana Martinez, Jocelyn E. Remmert, Aspara Nair, Umesh G. Lalloo, Nagalingeswaran Kumarasamy, James Hakim, Thomas B. Campbell, for the PEARLS (ACTG A5175) Study Team

published 25 Aug 2014

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Azvudine, A Novel Nucleoside Reverse Transcriptase Inhibitor Showed Good Drug Combination Features and Better Inhibition on Drug-Resistant Strains than Lamivudine In Vitro

Rui-Rui Wang, Qing-Hua Yang, Rong-Hua Luo, You-Mei Peng, Shao-Xing Dai, Xing-Jie Zhang, Huan Chen, Xue-Qing Cui, Ya-Juan Liu, Jing-Fei Huang, Jun-Biao Chang, Yong-Tang Zheng

published 21 Aug 2014

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Incidence and Determinants of Nevirapine and Efavirenz-Related Skin Rashes in West Africans: Nevirapine's Epitaph?

Fred Stephen Sarfo, Maame Anima Sarfo, Betty Norman, Richard Phillips, David Chadwick

published 11 Apr 2014

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Patterns of Transmitted HIV Drug Resistance in Europe Vary by Risk Group

Dineke Frentz, David van de Vijver, Ana Abecasis, Jan Albert, Osamah Hamouda, Louise Jørgensen, Claudia Kücherer, Daniel Struck, Jean-Claude Schmit, Jurgen Vercauteren, Birgitta Åsjö, Claudia Balotta, Colm Bergin, Danail Beshkov, Ricardo Camacho, Bonaventura Clotet, Algirdas Griskevicius, Zehava Grossman, Andrzej Horban, Tatjana Kolupajeva, Klaus Korn, Leondios Kostrikis, Kirsi Liitsola Marek Linka, Claus Nielsen, Dan Otelea, Dimitrios Paraskevis, Roger Paredes, Mario Poljak, Elisabeth Puchhammer-Stöckl, Anders Sönnerborg, Danica Stanekova, Maja Stanojevic, Anne-Mieke Vandamme, Charles Boucher, Annemarie Wensing31* on behalf of the SPREAD Programme

published 10 Apr 2014

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Clinically Relevant Transmitted Drug Resistance to First Line Antiretroviral Drugs and Implications for Recommendations

Susana Monge, Vicente Guillot, Marta Alvarez, Natalia Chueca, Natalia Stella, Alejandro Peña, Rafael Delgado, Juan Córdoba, Antonio Aguilera, Carmen Vidal, Federico García, CoRIS

published 17 Mar 2014

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Adherence as a Predictor of the Development of Class-Specific Resistance Mutations: The Swiss HIV Cohort Study

Viktor von Wyl, Thomas Klimkait, Sabine Yerly, Dunja Nicca, Hansjakob Furrer, Matthias Cavassini, Alexandra Calmy, Enos Bernasconi, Jürg Böni, Vincent Aubert, Huldrych F. Günthard, Heiner C. Bucher, Tracy R. Glass, and the Swiss HIV Cohort Study

published 16 Oct 2013

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Increased Risk of Q151M and K65R Mutations in Patients Failing Stavudine-Containing First-Line Antiretroviral Therapy in Cambodia

Janin Nouhin, Yoann Madec, Nicole Ngo-Giang-Huong, Laurent Ferradini, Eric Nerrienet

published 28 Aug 2013

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Population-Based Monitoring of Emerging HIV-1 Drug Resistance on Antiretroviral Therapy and Associated Factors in a Sentinel Site in Cameroon: Low Levels of Resistance but Poor Programmatic Performance

Serge C. Billong, Joseph Fokam, Avelin F. Aghokeng, Pascal Milenge, Etienne Kembou, Ibile Abessouguie, Flore Beatrice Meva’a-Onglene, Anne C. Zoung-Kanyi. Bissek, Vittorio Colizzi, Eitel N. Mpoudi, Jean-Bosco N. Elat, Koulla S. Shiro

published 26 Aug 2013

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