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Receptor binding assays

Structural similarity, characterization of Poly Ethylene Glycol linkage and identification of product related variants in biosimilar pegfilgrastim

Rakesh Shekhawat, Chintan Kumar Shah, Akash Patel, Sankaranarayanan Srinivasan, Poonam Kapoor, Suvaskumar Patel, Sharwan Kumar, Sandeep Sonar, Namrata More, Manasvi Joshi, Jatin Patel, Milan Vachhani, Bhargav Prasad Kodaganti, Upasana Choavatiya, Arabhi Pushpaja, Shubhangi Argade, Nidhi Nuwal, Manish Kumar, Sridevi Khambhampaty

published 13 Mar 2019

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Affinity, potency, efficacy, and selectivity of neurokinin A analogs at human recombinant NK2 and NK1 receptors

Nadia M. J. Rupniak, Elisabetta Perdona, Cristiana Griffante, Palmina Cavallini, Anna Sava, Daniel J. Ricca, Karl B. Thor, Edward C. Burgard, Mauro Corsi

published 25 Oct 2018

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Expression and purification of a functional heteromeric GABA_A receptor for structural studies

Derek P. Claxton, Eric Gouaux

published 20 Jul 2018

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Discovery of indolylpiperazinylpyrimidines with dual-target profiles at adenosine A_2A and dopamine D₂ receptors for Parkinson's disease treatment

Yi-Ming Shao, Xiaohua Ma, Priyankar Paira, Aaron Tan, Deron Raymond Herr, Kah Leong Lim, Chee Hoe Ng, Gopalakrishnan Venkatesan, Karl-Norbert Klotz, Stephanie Federico, Giampiero Spalluto, Siew Lee Cheong, Yu Zong Chen, Giorgia Pastorin

published 05 Jan 2018

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In Vitro comparison of ²¹³Bi- and ¹⁷⁷Lu-radiation for peptide receptor radionuclide therapy

Ho Sze Chan, Erik de Blois, Alfred Morgenstern, Frank Bruchertseifer, Marion de Jong, Wouter Breeman, Mark Konijnenberg

published 21 Jul 2017

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IGF1 and IGF2 specificities to the two insulin receptor isoforms are determined by insulin receptor amino acid 718

Mie Andersen, Dorte Nørgaard-Pedersen, Jakob Brandt, Ingrid Pettersson, Rita Slaaby

published 01 Jun 2017

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SPR-based fragment screening with neurotensin receptor 1 generates novel small molecule ligands

Sylwia Huber, Fabio Casagrande, Melanie N. Hug, Lisha Wang, Philipp Heine, Lutz Kummer, Andreas Plückthun, Michael Hennig

published 16 May 2017

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Mini-G proteins: Novel tools for studying GPCRs in their active conformation

Rony Nehmé, Byron Carpenter, Ankita Singhal, Annette Strege, Patricia C. Edwards, Courtney F. White, Haijuan Du, Reinhard Grisshammer, Christopher G. Tate

published 20 Apr 2017

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Comparison of cell-based assays for the identification and evaluation of competitive CXCR4 inhibitors

Anneleen Van Hout, Thomas D’huys, Merel Oeyen, Dominique Schols, Tom Van Loy

published 14 Apr 2017

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Levo-Tetrahydroberberrubine Produces Anxiolytic-Like Effects in Mice through the 5-HT_1A Receptor

Guiyun Mi, Shuai Liu, Jian Zhang, Huichun Liang, Yunyun Gao, Nuomin Li, Boyang Yu, Hongju Yang, Zheng Yang

published 13 Jan 2017

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Novel Bioluminescent Binding Assays for Ligand–Receptor Interaction Studies of the Fibroblast Growth Factor Family

Ge Song, Xiao-Xia Shao, Qing-Ping Wu, Zeng-Guang Xu, Ya-Li Liu, Zhan-Yun Guo

published 14 Jul 2016

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Examining the Effects of Sodium Ions on the Binding of Antagonists to Dopamine D₂ and D₃ Receptors

Claire L. Newton, Martyn D. Wood, Philip G. Strange

published 05 Jul 2016

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Genome-Wide SNP Discovery, Genotyping and Their Preliminary Applications for Population Genetic Inference in Spotted Sea Bass (Lateolabrax maculatus)

Juan Wang, Dong-Xiu Xue, Bai-Dong Zhang, Yu-Long Li, Bing-Jian Liu, Jin-Xian Liu

published 23 Jun 2016

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