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Proteomics

Delineating SARS-CoV-2 spike protein and antibodies interaction interfaces via siamese neural networks: A geometric and image-based analysis

Gemma Loreti, Paola Vottero, Elena Carlotta Olivetti, Enrico Vezzetti, Jack Tuszynski, Federica Marcolin, Maral Aminpour

published 04 Nov 2025

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Comprehensive analysis of cuproptosis-related genes in diabetic cardiomyopathy

Jun Li, Hua Zhang, Xinyue Duan, Meina Zhang, Xin Li, Chunyan Hao

published 27 Oct 2025

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ZPBP and fertility-associated proteomes as novel biomarkers: A shotgun proteomics approach in Murrah buffalo (Bubalus bubalis) bulls’ seminal plasma and cryopreserved spermatozoa

Hikmayani Iskandar, Syahruddin Said, Tulus Maulana, Ekayanti Mulyawati Kaiin, Berlin Pandapotan Pardede, Isyana Khaerunnisa, Widya Pintaka Bayu Putra, Raden Iis Arifiantini, Fuad Hasan, Göran Andersson, Sarmin Sarmin, Claude Mona Airin, Reski Amalia, Pudji Astuti

published 22 Oct 2025

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KIF18A induces the EMT process of hepatoma cells through the 5-LOX-dependent arachidonic acid pathway

Yibo Wang, Tao Cai, Yajie Chen, Wenpeng Liu, Baowang Liu, Xin Zhao, Yang Wang, Jinglin Cao, Qiang Zeng

published 13 Oct 2025

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DPP4 inhibitors as a novel therapeutic strategy in colorectal cancer: Integrating network biology and experimental insights

Sanaa K. Bardaweel, Baraa Abu Sneineh, Rima Hajjo, Reema Abu Khalaf

published 10 Oct 2025

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Identification of shared key genes in Rheumatoid Arthritis and COVID-19 and their relevance as diagnostic biomarkers and with immune infiltration: New insights from bioinformatics analysis

Wei Ya Lan, Shan Shan Cai, QianWei Lu, Fang Tang

published 09 Oct 2025

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Relation between proteome characterization and semen quality in Italian chicken breeds

Simona Nonnis, Elisa Maffioli, Joshua Grana, Manuela Madeddu, Luisa Zaniboni, Stefano Paolo Marelli, Vera Perricone, Nicolaia Iaffaldano, Gabriella Tedeschi, Silvia Cerolini

published 08 Oct 2025

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A graph neural network-based approach for predicting SARS-CoV-2–human protein interactions from multiview data

Sumanta Ray, Syed Alberuni, Alexander Schönhuth

published 25 Sep 2025

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Dual efficacy-toxicity of Chelidonii Herba in chronic obstructive pulmonary disease: Integrated network pharmacology, immune profiling and molecular docking

Guoliang Chen, Tianqing Wang

published 23 Sep 2025

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Dehydration does not drive host behavioural manipulation by hairworms

Louise M. Coates, Kieran Reynolds, Mara Carey-Wood, Dominika Lastik, Chris Vennard, Jean-François Doherty, Eddy Dowle, Benjamin J. Matthews, Leonard J. Foster, Stuart E. Reynolds, Vicky L. Hunt

published 23 Sep 2025

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Identification and 3D modeling of bioactive peptides from Lactobacillus brevis RAMULAB49 protein hydrolysate with in silico ERK1 phosphorylation inhibition activity targeting diabetic nephropathy

Reshma Mary Martiz, Ramith Ramu, Hemalatha Nambisan, Ameer Suhail, Mohammad Raish, Shashank M. Patil, Ashwini P., Mahesh B., Maciej Przybyłek, Piotr Bełdowski, Alina Sionkowska, Kefeng Li, Xijun Tang

published 22 Sep 2025

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KG-MACNF: A nonlinear cross-modal fusion model for predicting drug-target interactions via multi-relational embedding and fine-grained structure

Yihan Feng, Xixin Yang, Yuanlin Guan, Jinyao Zhang, Hang Yang, Zhongyu Wang, Qi Cheng

published 09 Sep 2025

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ProteinWeaver: A webtool to visualize ontology-annotated protein networks

Oliver Anderson, Altaf Barelvi, Aden O’Brien, Ainsley Norman, Iris Jan, Anna Ritz

published 05 Sep 2025

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