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Proteomics

Precision screening identifies mitoxantrone as a multitarget inhibitor in ageing-associated cancers with extensive computational validation and doxorubicin comparison

Mohammed H. Al-Qahtani, Mourad Assidi, Abdelbaset Buhmeida, Asma Almuhammadi, Peter Natesan Pushparaj, Nofe Ateq Alganmi

published 13 Feb 2026

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In-silico target prediction and pathway analysis of propranolol as a potential therapeutic agent for hepatocellular carcinoma

Ishaq Ahmad, Shakeel Ahmad Khan, Muhammad Abu Bakar, Adnan Shakoor, Abdul Wasy Zia

published 13 Feb 2026

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MAGIN-GO: Protein function prediction based on dual graph neural networks and gene ontology structure

Runxin Li, Wentao Xie, Zhenhong Shang, Xiaowu Li, Guofeng Shu, Lianyin Jia, Wei Peng

published 09 Feb 2026

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Evaluating global measures of network centralization: Axiomatic and numerical assessments

Majid Saberi, Samin Aref

published 05 Feb 2026

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Effects of silybin on triptorelin-induced bone metabolic abnormalities in prostate cancer revealed based on TMT-based proteomics

Jianhui Li, Xuejiao Lv, Ying Jiang

published 29 Jan 2026

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Identifying biomarkers for diagnosis and disease activity monitoring in PSC-IBD and UC through proteomic profiling: A prospective, biomarker discovery single-center study protocol

Ondrej Fabian, Lukas Bajer, Peter Macinga, Jan Brezina, Mojmir Hlavaty, Pavel Drastich, Pavel Wohl, Karel Harant, Pavel Talacko, Eva Sticova, Andrea Vajsova, Alena Bohdanecka, Filip Tichanek, Monika Cahova

published 27 Jan 2026

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In silico evaluation of bioactive compounds from the sea urchin Temnopleurus toreumaticus: Potential multifunctional agents against mosquito vectors and tropical pathogens

Karnan Ramachandran, Senthil Bakthavatchalam, Velavan Sivanandham, Shunmuga Vadivu Ramalingam, Pitchaimuthu Mariappan, Renganathan Senthil, Chandramohan Govindasamy, Khalid S. Al-Numair, Ramachandran Vinayagam, Zhi-Hong Wen, Hsien-Kuo Chin

published 23 Jan 2026

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Multi-modal data to identify key factors influencing lung injury in ARDS patients undergoing invasive mechanical ventilation: A prospective multi-center observational study protocol

Zhimei Duan, Di Lian, Kaifei Wang, Ye Hu, Han Fu, Ruoxuan Wen, Ying Zhao, Xingshuo Hu, Pan Pan, Jianqiao Xu, Jin Chen, Li Xiao, Lin Wang, Xiao Yu, Xiaobo Han, Wuxiang Xie, Fei Xie, Lixin Xie, Zhihai Han

published 23 Jan 2026

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Integrative multi-omics analyses identify key genes and elucidate bidirectional regulatory mechanisms in thyroid dysfunction

Yilang Hu, Hong Hu, Lijun Xu, Xuzheng Tang, Chongyu Wang, Zhengyi Lian, Chenyu Xie, Zhiwan Xie, Qingqing Wang

published 22 Jan 2026

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Paleo-proteomic analysis of Iron Age dental calculus provides direct evidence of Scythian reliance on ruminant dairy

Jaruschka Pecnik, Alicia R. Ventresca Miller, Christian Panse, Laura Kunz, Antje Dittmann, James A. Johnson, Sergey Makhortykh, Ludmilla Litvinova, Svetlana Andrukh, Gennady Toschev, Michael Krützen, Verena J. Schuenemann, Shevan Wilkin

published 21 Jan 2026

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Mono-mix strategy enables comparative proteomics of a cross-kingdom microbial symbiosis

Sunnyjoy Dupuis, Usha F. Lingappa, Samuel O. Purvine, Lauren Chiang, Sean D. Gallaher, Carrie D. Nicora, Mary S. Lipton, Sabeeha S. Merchant

published 16 Jan 2026

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Mechanisms of cellular senescence combined with molecular docking strategies: A biomarker study of potential therapeutic targets for allergic rhinitis

Qingyong Chen, Han Zhang, Yue Wu, Jixin Liu, Dongqing Wang, Dezhong Sun, Zhipeng Chen, Liqiang Lin, Huaiqing Lv, Qiang Shao

published 09 Jan 2026

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Investigation mechanisms of action and resistance of Edwardsiella ictaluri to trans-cinnamaldehyde

Hossam Abdelhamed, Munshi Mustafiz Riman, Mark A. Arick II, Ali Sobhy Dawood, Basant Gomaa, Monzur Chowdhury, Larry A. Hanson, Attila Karsi

published 07 Jan 2026

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